Navigation Links
Carbon dioxide's new-found signalling role could be applied to blood flow, birth and deafness
Date:11/13/2013

ings and other mammals produce huge amounts of it every day.

"The exciting implication of our study is that carbon dioxide is much more than just a waste product: it can directly signal physiological information, and our work shows the mechanism by which this happens via Connexin 26.

"As Connexin 26 is present in many tissues and organs, for example the brain, skin, inner ear, liver and the uterus during pregnancy, this discovery should herald a re-evaluation of the potential for carbon dioxide signalling in many different processes such as the control of blood flow, breathing, hearing, reproduction and birth."

Connexin 26 comprises six identical subunits. Carbon dioxide makes a chemical bond to the side chain a particular amino acid. This modified side chain can then form a bridge to a closely oriented amino acid in the adjacent subunit. A total of six carbon dioxide molecules can bind to make six bridges between subunits. These bridges force the Connexin 26 protein to alter its conformation thereby signalling the presence and concentration of carbon dioxide.


'/>"/>

Contact: Luke Harrison
luke.harrison@warwick.ac.uk
University of Warwick
Source:Eurekalert

Page: 1 2

Related biology news :

1. Drilling for hydrocarbons can impact aquatic life
2. Companies close to reusing the greenhouse gas carbon dioxide
3. Lawrence Livermore researchers unveil carbon nanotube jungles to better detect molecules
4. Carbon storage recovers faster than plant biodiversity in re-growing tropical forests
5. Polycyclic aromatic hydrocarbons in smokeless tobacco products
6. U.Va. researcher: Methane out, carbon dioxide in?
7. Carbonation alters the minds perception of sweetness
8. Carbon farming schemes should consider multiple cobenefits
9. Extreme weather, climate and the carbon cycle
10. Soil carbon blowing in the wind
11. Tropical ecosystems regulate variations in Earths carbon dioxide levels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... can take up residence in and on the human ... symptom, according to new research at Washington University School ... healthy individuals carry about five types of viruses on ... Central Biology . The study is the first comprehensive ... people. , The research was conducted as part ...
(Date:9/16/2014)... interaction between viruses, bacteria, and their environment is ... collaboration between Matthew Sullivan, associate professor in the ... Biology and Steven Hallam from the University of ... are drivers of nutrient and energy cycles that ... is changing, so are the environments these bacteria ...
(Date:9/16/2014)... 2014 Schizophrenia is associated with increased rates and ... research suggests that the relationship between schizophrenia and smoking ... use nicotine to self-medicate symptoms and cognitive impairment associated ... the current issue of Biological Psychiatry , sheds ... level of nicotine receptors in the brain was lower ...
Breaking Biology News(10 mins):Healthy humans make nice homes for viruses 2Healthy humans make nice homes for viruses 3New research decodes virus-host interactions in ocean dead zones 2New research decodes virus-host interactions in ocean dead zones 3Smoking and schizophrenia linked by alterations in brain nicotine signals 2
... For two weeks in March, some of the greatest names ... take part in public discussions on how fundamental discoveries in ... understanding of life and civilization -- and our grasp of ... & Life of Beginnings," this one-of-a-kind program was organized by ...
... Global climate rapidly shifted from a relatively ice-free world ... 34 million years ago. What happened? What changed? ... a new perspective on the nature of changing climatic ... and has important implications for predicting future climate changes. ...
... CLEMSON, SCIn areas of the U.S. where golfers can ... traffic, and frost can wreak havoc on healthy greens ... Creeping bentgrass ( Agrostis stolonifera var. palustris Huds. ), ... is often preferred because of its year-round green color, ...
Cached Biology News:World's top minds to celebrate 'the birth and life of beginnings' 2World's top minds to celebrate 'the birth and life of beginnings' 3World's top minds to celebrate 'the birth and life of beginnings' 4CO2 drop and global cooling caused Antarctic glacier to form 2This grass is still greener 2
(Date:9/15/2014)... An interdisciplinary team of researchers led by Northeastern ... constructing precise inter-nanotube junctions and a variety of ... is facile and easily scalable, which will allow ... nanotube networks for use in applications ranging from ... everything from cars to sports equipment. , Their ...
(Date:9/15/2014)... 15, 2014 Zymo Research Corp., has announced ... for safe ambient temperature storage and transport of ... infectivity of agents in such samples is completely ... of the viral nucleic acids for subsequent analyses.  ... epidemic in West Africa ...
(Date:9/15/2014)... DUBLIN , Sept. 15, 2014 Research ... "Whole Exome Sequencing Market by Product, by Services, by Technology, ... their offering. Whole Exome Sequencing (WES) is ... the genome, i.e. the exon. The exome, which is the ... of the total genome and is actually converted into proteins ...
(Date:9/15/2014)... (PRWEB) September 15, 2014 Applied ... implantable silicones for the medical device and critical ... gel for the implantable medical device market. ... crosslink technology delivering a silicone gel with improved ... Dual Matrix technology consists of two crosslinked networks ...
Breaking Biology Technology:Northeastern University Researchers Develop Novel Method for Working with Nanotubes 2Safe storage and transport of Ebola, Mers-CoV, and other viruses: Groundbreaking viral inactivation solution capable of preserving nucleic acids 2Safe storage and transport of Ebola, Mers-CoV, and other viruses: Groundbreaking viral inactivation solution capable of preserving nucleic acids 3Global Whole Exome Sequencing (Systems, Kits, Library Preparation, Target Enrichment) Market by Product, by Services, by Technology, by Application - Forecast to 2018 2Global Whole Exome Sequencing (Systems, Kits, Library Preparation, Target Enrichment) Market by Product, by Services, by Technology, by Application - Forecast to 2018 3Applied Silicone Launches Silicone Gel System with Dual Matrix Technology 2
... Almost everybody knows the University of Wisconsin-Madison ... But a new study has produced figures to back ... in the University Research Park , located three ... university research. And the concentration of these innovative firms, ...
... has heard of identity theft (IDT), yet unless you have ... high risk. An alarming figure is that over half of ... place of business, employer, or other entity (not-for-profit or local, ... are required under one or more federal and state laws ...
... Madison-based National Stem Cell Bank has announced it ... of California-San Francisco , giving it 13 of the 21 ... Donley, executive director of the WiCell Research Institute , ... optimistic that it eventually will have all 21 federally approved ...
Cached Biology Technology:Impact of research park firms pegged at $680M 2Identity theft: The business time bomb 2Identity theft: The business time bomb 3Identity theft: The business time bomb 4Nation's only stem cell bank will receive UC-San Francisco cell line 2
... NeuroLog System is a compact, versatile & modular ... of purposes including: Intracellular, Extracellular, Transducer & ... The NeuroLog Case & Power Supply unit (NL900D) ... Modules are not only powered by this unit, ...
Rat Epidermal Keratinocytes (REK) (>500,000 cells)...
... Precision Model 410 is a four-channel general purpose ... small signals from sources which may have a ... channel consists of a high gain/low noise amplifier, ... and an output offset control. A control knob ...
Porcine Coronary Artery Endothelial Cells (PCAEC) (>500,000 cells)...
Biology Products: