Navigation Links
Cancer scientists discover new way breast cancer cells adapt to environmental stress
Date:5/14/2011

ood in order to flourish where healthy cells would not survive."

"Our discovery that deprivation of either sugar or oxygen spurs CPT1C expression in tumour cells marks this protein as a potential target for new drug development," says Dr. Mak.

"We also demonstrated that cells that were prevented from using CPT1C to cope with a disruption in sugar metabolism became more sensitive to environmental stress. These findings represent an important stepping stone to developing targeted therapies that can block cancer cells from adapting to environmental challenges and surviving efforts to kill them."

This most recent discovery builds on Dr. Mak's impressive body of work, which has led to important breakthroughs in immunology and our understanding of cancer at the molecular level. Dr. Mak is internationally renowned for his 1984 landmark scientific paper on the cloning of the genes for the T cell receptor, a key component of the human immune system.


'/>"/>

Contact: Geoff Koehler
geoff.koehler@uhn.on.ca
416-340-4800
University Health Network
Source:Eurekalert

Page: 1 2

Related biology news :

1. AAPS national biotechnology conference to highlight breakthrough cancer treatments
2. UT Southwestern researchers find protein that might be key to cutting cancer cells blood supply
3. Yale researchers explain why cancer smart drugs may not be so smart
4. Microbubble-delivered combination therapy eradicates prostate cancer in vivo
5. Parsley, celery carry crucial component for fight against breast cancer, MU researcher finds
6. Medusa-structure of gene regulatory network: Dominance of transcription factors in cancer subtypes
7. UT Southwestern research reveals how cancer-driving enzyme works
8. Einstein researchers find key gene in childhood cancer
9. Racial disparities still exist in colorectal cancer screening despite increased Medicare coverage
10. Hitting target in cancer fight now easier with new nanoparticle platform, UCLA scientists say
11. High percentage of omega-3s in the blood may boost risk of aggressive prostate cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... , Jan. 15, 2015  BellBrook Labs, a leader ... announced the launch of a TR-FRET (time resolved ... Transcreener UDP Assay, a high throughput screening assay ... assay will allow for sensitive detection of hundreds ...
(Date:1/22/2015)... MUNICH , January 22, 2015 ... its tenth year  The European Patent Office to present ... Two British nominations to be featured: Christofer Toumazou ... week featuring former finalists and winners of the Award   ...
(Date:12/22/2014)... , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, announces ... Apollo Robbins for the 2015 International CES debut of ... Robbins will be at the NXT-ID booth January 6th ...
Breaking Biology News(10 mins):BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4
... resulting from the nations nuclear weapons program lie in ... Beneath this desert landscape about two million curies ... chemicals are captured within the stratified vadose zone below ... These paths create uncertainties about where the contaminants go ...
... including those who helped decode the entire human genome ... 1mm long. The potato cyst nematode (PCN), Globodera ... particularly devastating in developing countries where the potato is a ... of Leeds to fully sequence its DNA, hopes to shed ...
... 26 Stinger Systems, Inc.,(OTC Bulletin Board: STIY), a ... Sheriff,s Department in Kansas has,purchased Stinger Systems, S-200 projectile ... the Stinger S-200 and,clearly felt that its features were ... the ruggedness of the product as well as its ...
Cached Biology News:Where does stored nuclear waste go? 2New research to decode the genetic secrets of prolific potato pest 2
(Date:1/22/2015)... , Jan. 22, 2015   GenoSpace , a precision medicine ... to enable the broad use of genomic, imaging and other ... appointment of Michelle Munson , CEO of Aspera, an ... Logo - http://photos.prnewswire.com/prnh/20150122/170713 "We ...
(Date:12/24/2014)... YORK , Dec. 24, 2014 PlasmaTech Biopharmaceuticals, Inc. ... critical areas, announced the closing of an underwritten public offering ... up to an aggregate 3,500,000 shares of common stock, at ... warrant.  The warrants have a per share exercise price of ...
(Date:12/24/2014)... 2014 GMO corn cases filed across the ... the process of being consolidated in a Kansas federal court ... AG MIR 162 Corn Litigation, MDL No. 2591 in the ... of the Syngenta GMO corn multidistrict litigation (MDL) has been ...
(Date:12/24/2014)... Island, New York (PRWEB) December 23, 2014 ... and the Long Island Affiliate of ITRA Global, the national ... slow but steady recovery. This is evidenced by the ... the strong stock market. Low energy costs have held ...
Breaking Biology Technology:GenoSpace Expands Board with Appointment of Michelle Munson 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3
... Wis . - Non-controlling shareholders of Billerica, Mass.-based ... for the $135 million acquisition of their affiliate molecular ... firms are part of the Bruker family of companies, ... ,Bruker Optics produces a variety of spectrometers, including Fourier ...
... - The soaring prices of oil and natural gas ... matter instead of petroleum, and both biodiesel and gasoline containing ... , ,But the oil price hike has also fueled ... compounds that are the raw material for many modern plastics, ...
... Despite recent legislative setbacks, proponents of net neutrality said ... members of the United States Senate not to take ... provisions are included. , ,The pro-neutrality group It'sOurNet ... Senate to reject the telecommunications bill following a tie ...
Cached Biology Technology:UW prof turns sugar into diesel fuel, chemicals 2UW prof turns sugar into diesel fuel, chemicals 3Net neutrality will be back, supporters vow 2Net neutrality will be back, supporters vow 3Net neutrality will be back, supporters vow 4
Human VEGF R Phycoerythrin Sampler (Cl 89106, 49560, 54733)...
RABBIT ANTI NEOPTERIN...
MOUSE ANTI SIMIAN VIRUS 5:FITC Immunogen: Simian virus 5...
... • Dog serum is collected from fasted mixed ... age Available Anticoagulants: N-02: ... K2EDTA N-08: Potassium Oxalate ... N-05: ACD N-07: CPD ...
Biology Products: