Navigation Links
Cancer data not readily available for future research
Date:7/13/2011

Durham, NC A new study finds that -- even in a field with clear standards and online databases -- the rate of public data archiving in cancer research is increasing only slowly. Furthermore, research studies in cancer and human subjects are less likely than other research studies to make their datasets available for reuse.

The results come from a study of patterns of research data availability conducted by Dr Heather Piwowar of the National Evolutionary Synthesis Center.

Data collected in scientific research is often useful for future studies by other investigators, but scientists have rarely made their raw research data widely available. Tools and initiatives are underway to encourage scientists to publicly archive their data. This analysis confirms there is still much room for improvement.

By querying the full text of the scientific literature through websites like Google Scholar and PubMed Central, Piwowar identified eleven thousand studies that collected a particular type of data about cellular activity, called gene expression microarray data. Only 45% of recent gene expression studies were found to have deposited their data in the public databases developed for this purpose. The rate of data publication has increased only slightly from 2007 to 2009. Data is shared least often from studies on cancer and human subjects: cancer studies make their data available for wide reuse half as often as similar studies outside cancer.

"It was disheartening to discover that studies on cancer and human subjects were least likely to make their data available. These data are surely some of the most valuable for reuse, to confirm, refute, inform and advance bench-to-bedside translational research," Piwowar said.

"We want as much scientific progress as we can get from our tax and charity dollars. This requires increased access to data resources. Data can be shared while maintaining patient privacy," Piwowar added, noting that patient re-identification is rarely an issue for gene expression microarray studies.

Most likely to share their data in public databases were investigators from Stanford University and those who published in the journal Physiological Genomics.

Scientist sometimes email each other to request datasets that aren't available online, but these requests often go unanswered or are denied by the original investigators. Publishing data in online data repositories is considered the best way to share data for future reuse.

Recent policies by the NSF seek to increase the amount of data disseminated from federally-funded research by requiring data management and dissemination plans in all new grant applications.


'/>"/>

Contact: Heather Piwowar
hpiwowar@nescent.org
919-668-4544
National Evolutionary Synthesis Center (NESCent)
Source:Eurekalert

Related biology news :

1. UT faculty improving surgical outcomes for children, cancer patients
2. Study explains why men are at higher risk for stomach cancer
3. Stem cells restore cognitive abilities impaired by brain cancer treatment
4. PSA test for men could get a second life for breast cancer in women
5. Low dose naltrexone (LDN): Harnessing the bodys own chemistry to treat human ovarian cancer
6. GNS Healthcare Collaborates with NCI in New Approach to Lung Cancer; Supercomputer Analysis to Aid in Matching Targeted Drugs to Patients
7. AACR hosts Frontiers in Basic Cancer Research Conference in San Francisco
8. University of Houston researcher an author of multi-institutional genetic study of ovarian cancer
9. TGen presents lung cancer studies at Amsterdam conference
10. Southern US states lag in reducing death rates from colorectal cancer
11. Damon Runyon Cancer Research Foundation awards prestigious fellowships to 18 top young scientists
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/6/2017)... Jan. 5, 2017  Delta ID Inc., a leader ... technology for automotive at CESĀ® 2017. Delta ID has ... to demonstrate the use of iris scanning as a ... the driver in a car, and as a way ... experience. Delta ID and Gentex will demonstrate ...
(Date:1/4/2017)... VEGAS , Jan. 4, 2017  CES ... performance biometric sensor technology, today announced the launch ... sensor systems, the highly-accurate biometric sensor modules ... biometric technology, experience and expertise. The two ... Benchmark designed specifically for hearables, and Benchmark BW2.0, ...
(Date:12/22/2016)... , Dec. 20, 2016  As part of its ... the leading personal genetics company, recently released its latest children,s ... . The book focuses on the topics of inheritance and ... Science Standards (NGSS) taught in elementary school classrooms in the ... a series by illustrator Ariana Killoran , whose previous ...
Breaking Biology News(10 mins):
(Date:1/17/2017)... YORK , Jan. 17, 2017 ... grow at a CAGR of around 7.5% over ... by 2025. Some of the prominent trends that ... growing incidences of diseases & graft transplant surgeries ... on Material the market is categorized into immunomodulatory ...
(Date:1/17/2017)... 17, 2017 Roka Bioscience, Inc. (NASDAQ: ROKA ... for the detection of foodborne pathogens today announced the appointment of ... Paul Thomas , the Company,s President and CEO since 2009, ... of Directors.  The changes are effective today. In addition, ... ...
(Date:1/17/2017)... --  Pulmatrix, Inc . (NASDAQ: PULM ), ... to address serious pulmonary diseases, today announced that its ... of CF patients, PUR1900, has been designated as a ... & Drug Administration. Under the QIDP ... of novel drugs against important pathogens, Pulmatrix will receive ...
(Date:1/17/2017)... Research and Markets has announced the ... Technologies, Markets and Companies" to their offering. ... The number ... the past few years. More than 1,000 companies have been ... of these are profiled in the report along with tabulation ...
Breaking Biology Technology: