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Cancer-causing bacterium targets tumor-suppressor protein
Date:8/2/2010

RUNX3 "could produce conditions in which aberrant cellular changes are less inhibited," Chen said.

Chen's group is working to identify the molecular mechanism by which CagA targets RUNX3 for degradation. He and his colleagues hope to design small molecules that can specifically inhibit the interaction between RUNX3 and CagA and block the degradation of RUNX3. Such drugs may be used to prevent the gastric diseases induced by H. pylori.


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Contact: Diana Yates, Life Sciences Editor
diya@illinois.edu
217-333-5802
University of Illinois at Urbana-Champaign
Source:Eurekalert  

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Cancer-causing bacterium targets tumor-suppressor protein
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