These studies suggest that B cells can have dual roles in diabetes and possibly other autoimmune diseases. The B cells might promote disease initially, but after being reconstituted following initial depletion with rituximab, they actually block further disease, Shlomchik added. This means that multiple rounds of medication to deplete the B cells might not be necessary or even advisable.
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| Contact: Jacqueline Weaver jacqueline.weaver@yale.edu 203-432-8555 Yale University Source:Eurekalert |