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Cancer Research Institute invests $450k in Oncovir to manufacture powerful immune stimulant
Date:1/21/2011

ectual property portfolio, maximizing the potential for future financial returns and the impact of philanthropic support to CVAF."

The CVAF agreement with Oncovir is the second to be completed since the fund's public launch in late 2010. The first, a collaborative research agreement with the Cambridge, MA, biotechnology company Tolerx, Inc., provides for $1.5 million in research funding to support Tolerx's clinical development of TRX518, a monoclonal antibody designed to enhance the immune system by enabling T cells to attack cancer cells more effectively. TRX518 is the first anti-GITR (glucocorticoid-induced tumor necrosis factor receptor) drug candidate to enter human clinical trials. Upon completion of the phase I study, TRX518 may be evaluated in clinical trials in combination with therapeutic cancer vaccines that could complement TRX518's effect on T cells.


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Contact: Brian M. Brewer
bbrewer@cancerresearch.org
212-688-7515
Cancer Research Institute
Source:Eurekalert

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