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Cancer Research Institute invests $450k in Oncovir to manufacture powerful immune stimulant
Date:1/21/2011

NEW YORK, NY, Jan. 21, 2011 Cancer Research Institute, Inc. (CRI), a U.S. nonprofit organization founded in 1953 to advance the science of tumor immunology and foster the discovery and development of new cancer immunotherapies, announced today that its Cancer Vaccine Acceleration Fund (CVAF), a joint initiative with the Ludwig Institute for Cancer Research (LICR), has completed a new investment agreement with Oncovir, Inc., a biotechnology company based in Washington, D.C., to enable the production of the immunological stimulant Hiltonol (Poly-ICLC).

"CVAF support is a critical factor enabling the manufacture of enough high-grade Hiltonol for clinical testing not only in cancer vaccines, but also for many other diseases for which it holds promise," says Andres M. Salazar, M.D., founder, chief executive officer, and scientific director of Oncovir.

Through the collaboration, CVAF will provide $450,000 to Oncovir to help fund the manufacture of clinical grade Hiltonol. As part of the agreement, 10,000 vials of Hiltonol will be dedicated exclusively for use in 10 to 15 early- and mid-phase clinical trials designed and conducted within the CRI/LICR Cancer Vaccine Collaborative (CVC), a coordinated global network of 19 academic clinical trial sites and advanced immunological monitoring laboratories. Since it was established in 2001, the CVC has completed more than 22 early-phase clinical trials of different, multi-component cancer vaccine formulations, with an additional 21 trials currently ongoing and 4 more planned to begin patient accrual.

Members of the CVC's Coordinating and Review Committee have identified Hiltonol as a powerful immunomodulator with the potential to enhance the efficacy of therapeutic cancer vaccines. In addition to holding a dedicated supply of Hiltonol, CVAF will also receive a perpetual non-exclusive license for the agent's use in combination with therapeutic cancer vaccines, according to the terms of the agr
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Contact: Brian M. Brewer
bbrewer@cancerresearch.org
212-688-7515
Cancer Research Institute
Source:Eurekalert

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