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Canadian researchers lead groundbreaking discovery in deadly childhood cancer
Date:12/11/2013

at all. From a clinical point of view, the results of this study suggest DNMT3B may be a suitable target for future therapies designed to combat ETMR/ETANTR.

"We now want to see if we can control the production of the enzyme in the tumour, and if doing so enables us to stall its growth," says Dr. Jabado who is also a researcher in Medical Genetics and Genomics at the RI-MUHC.

"This is a great example of how research can produce exciting and at times groundbreaking results, and we are thrilled to have contributed to this study that will hopefully help to save children's lives, and hopefully get more studies of its kind off the ground," states Andy Chabot, President and CEO of the Cancer Research Society.

Findings from this study will be added to a global tumour registry and ETMR/ETANTR tumour bank established by Dr. Huang, which has collected nearly 100 of these rare tumours to date. Although more research is needed, the prospects for developing an effective treatment are becoming steadily brighter as scientists learn more about ETMR/ETANTR. Importantly, these findings highlight how studying rare pediatric brain tumours can provide invaluable insight into unsuspected molecular mechanisms of brain development.


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Contact: Julie Robert
julie.robert@muhc.mcgill.ca
514-934-1934 x71381
McGill University Health Centre
Source:Eurekalert

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