Canadian biomedical engineering pioneer receives internati...(ormation on artificial surfaces; biocomp...)

"His literature contributions have guided the work of countless biomaterials scientists," said Heather Sheardown, associate professor of chemical engineering at McMaster. "Another of John's important contributions is in the training of a new generation of biomaterials scientists who have gone on to work in academia and industry, continuing to advance the field and carrying with them a passion ignited during their time in the Brash lab."

Prof. Brash has trained some 50 Masters, PhDs and postdoctoral fellows. He is also called on to consult with numerous biomaterials-related companies.

"Dr. Brash, whether interacting with fellow chemical engineers, biomaterials scientists or clinicians, has had a significant influence on the evolution of the field of biomaterials," said Stuart Cooper, professor and chair of the department of chemical and biomolecular engineering, at Ohio State University.

Discoveries by Prof. Brash can be found in some of Canada's most successful biomedical companies including Interface Biologics Inc. of Toronto and Angiotech Inc. in Vancouver.

"The latter part of the 80s and early 90s ushered in the concept of designing biomaterials that were pro-active in their interaction with proteins and cells," explains Prof. Santerre, who is also chief scientific officer and co-founder of Interface Biologics. "John's program in polyurethane research was among the first to build-in functional monomers that would capitalize on simulating the natural mechanisms of anti-coagulant function. Today, the bioactive concept is revolutionizing medical devices by merging the biopharmaceutical field and medical device sector to deliver implant therapies that accelerate healing associated with serious diseases."

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