Navigation Links
Can micro-scaffolding help stem cells rebuild the brain after stroke?
Date:4/11/2008

Inserting tiny scaffolding into the brain could dramatically reduce damage caused by strokes the UK National Stem Cell Network Annual Science Meeting will hear today. With funding from the Biotechnology and Biological Sciences Research Council (BBSRC) neurobiologists from the Institute of Psychiatry and tissue engineers from The University of Nottingham have joined forces to tackle the challenge of tissue loss as a result of stroke.

Speaking at the conference in Edinburgh, Dr Mike Modo from the Institute of Psychiatry will explain how combining scaffold microparticles with neural stem cells (NSCs) could regenerate lost brain tissue.

Strokes cause temporary loss of blood supply to the brain which results in areas of brain tissue dying causing loss of bodily functions such as speech and movement. Neural Stem Cells offer exciting possibilities for tissue regeneration, but there are currently major limitations in delivering these cells to the brain. And while NSC transplantation has been proven to improve functional outcomes in rats with stroke damage little reduction in lesion volume has been observed.

The research is being carried out by Dr Mike Modo and Professor Jack Price from the Institute of Psychiatry and Professor Kevin Shakesheff from The University of Nottingham.

Their findings are being presented at the UK National Stem Cell Network Inaugural Science Meeting at the Edinburgh Conference Centre on 10 April 2008. The conference is a showcase of the best and latest UK stem cell science across all stem cell disciplines.

Working with rats, Dr Modo and his team are developing cell-scaffold combinations that could be injected into the brain to provide a framework inside the cavities caused by stroke so that the cells are held there until they can work their way to connect with surrounding healthy tissue.

Dr Modo explains: "We propose that using scaffold particles could support NSCs in the cavity to re-f
'/>"/>

Contact: Dr. Mike Modo
mike.modo@iop.kcl.ac.uk
44-020-778-485-315
University of Nottingham
Source:Eurekalert

Page: 1 2

Related biology news :

1. ESF EURYI award winner aims to stop cancer cells reading their own DNA
2. Newly created cancer stem cells could aid breast cancer research
3. AIDS interferes with stem cells in the brain
4. Clemson scientists shed light on molecules in living cells
5. Social habits of cells may hold key to fighting diseases
6. UF scientists reveal how dietary restriction cleans cells
7. Human derived stem cells can repair rat hearts damaged by heart attack
8. Scientists identify embryonic stem cells by appearance alone
9. Cells united against cancer
10. Pittsburgh scientists identify human source of stem cells with potential to repair muscle
11. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... and pathogens that devastate honeybees in Europe, Asia and ... do not appear to be impacting native honeybee populations ... researchers., The invasive pests include including Nosema microsporidia ... honeybees appear to be resilient to these invasive pests, ... control pests in Europe, Asia and the United States ...
(Date:4/17/2014)... many serious conditions such as heart disease, epilepsy and ... therapies. Unfortunately, there is still much scientists do not ... and unexpected insight into the structure of sodium channels ... - which are responsible for ,fine-tuning, the activity of ... recent edition of the Journal of Biological Chemistry ...
(Date:4/17/2014)... researchers have detected new early-warning signs of the potential ... have far-reaching implications for the diagnosis and treatment of ... million Americans. , "We had not expected to see ... stages," said Ann Elsner, professor and associate dean in ... the study. "We set out to study the early ...
Breaking Biology News(10 mins):East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3Structure of sodium channels different than previously believed 2New technique detects microscopic diabetes-related eye damage 2New technique detects microscopic diabetes-related eye damage 3
... international consortium of 15 institutions from 12 European ... Norway, Romania, Sweden, The Netherlands, UK) has started ... The name stands for ,Biodiversity and Ecosystem Services: ... the effectiveness of arguments used for biodiversity protection ...
... the Arctic Ocean, the frozen soils within this region keep ... the Earth,s atmosphere. This sequestered carbon is more than 250 ... United States in the year 2009. As global temperatures slowly ... upon the carbon cycle when the permafrost thaws and releases ...
... metal-organic frameworks, with their nanoscopic pores and incredibly ... gas storage. But with millions of different structures ... University research team has developed a computational method ... in the discovery process. The new algorithm automatically ...
Cached Biology News:Preparing for a thaw: How Arctic microbes respond to a warming world 2Preparing for a thaw: How Arctic microbes respond to a warming world 3More promising natural gas storage? 2
(Date:1/14/2014)... owners drew up their lists of New Year,s resolutions for 2014, ... my furry companion." Nowadays there are pet salons, dog and cat ... the little canine or feline darlings along wherever mommy or daddy ... toys at the pet store. But anyone who has ever lived ...
(Date:1/14/2014)... MA (PRWEB) January 14, 2014 iLab Solutions, ... Detwiler as the new Director of Product Strategy. In this ... well as iLab sub-teams to guide in the development of ... iLab provides the maximum possible benefit to the scientific community ...
(Date:1/14/2014)... Ontario , Jan. 14, 2014   Kinaxis ®, provider ... SCM ) and sales and operations planning ( S&OP ) ... Biomanufacturing Summit , which will be held at the ... the conference, join Kinaxis customer Elisabeth Kaszas , Director ...
(Date:1/14/2014)... Independent publisher Bitingduck Press, with offices in Altadena ... ideas for 2014 in production and sales of interactive ... high-quality, low-cost, DRM-free ebooks and to use the sales ... first major development will be bookstore sales in local ...
Breaking Biology Technology:New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2Bitingduck Press Looks Forward to 2014 With Multimedia E-books 2
... 18 Opsona Therapeutics, a,biotechnology company focused on ... diseases, today announced the,completion of an EUR18M ($23M) ... expand both at an operational and clinical level. ... and Seroba Kernel,Life Sciences all participated in the ...
... Forschungsgemeinschaft (DFG, German Research Foundation) has announced that ... high-risk research projects. The Joint Committee of Germany,s ... approved funding for two new Reinhart Koselleck Projects. ... Professor Reinhard Drner, an atomic physicist from Frankfurt, ...
... found that tiny nanoparticles could be twice as likely ... liquids than previously believed. This opens up a ... in living cells, polymer composites, and high-tech foams, ... ways of further artificially enhancing this new found sticking ...
Cached Biology Technology:Opsona Therapeutics Closes EUR18M Funding 2Opsona Therapeutics Closes EUR18M Funding 3Opsona Therapeutics Closes EUR18M Funding 4Encouraging high-risk research: DFG approves funding for 2 new Reinhart Koselleck projects 2Encouraging high-risk research: DFG approves funding for 2 new Reinhart Koselleck projects 3Nanoparticles double their chances of getting into sticky situations 2
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
... Rabbit monoclonal [EP282Y] to Asparagine ... all tested applications). ... corresponding to residues in the ... Entrez GeneID: ...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Biology Products: