Navigation Links
Can genetic information be controlled by light?
Date:10/10/2008

This release is available in German.

DNA, the molecule that acts as the carrier of genetic information in all forms of life, is highly resistant against alteration by ultraviolet light, but understanding the mechanism for its photostability presents some puzzling problems. A key aspect is the interaction between the four chemical bases that make up the DNA molecule. Researchers at Kiel University have succeeded in showing that DNA strands differ in their light sensitivity depending on their base sequences. Their results are reported by Nina Schwalb and colleagues in the current issue of the journal Science appearing on October 10, 2008.

It has been known for many years that the individual bases that code the genetic information contained in DNA show a high degree of photostability, as the energy that they take up from UV radiation is immediately released again. Surprisingly, however, it is found that in DNA, which consists of many bases, those mechanisms are ineffective or only partially effective. It seems that the deactivation of UV-excited DNA molecules must instead occur by some completely different mechanisms specific to DNA, which are not yet understood. Through measurements by a variety of methods on DNA molecules with different base sequences, the research group led by Professor Friedrich Temps at the Institute of Physical Chemistry of Kiel University has now been able to confirm and clarify that assumption.

According to Professor Temps, "DNA achieves its high degree of photostability through its complex double-helix structure. The interactions between bases that are stacked one above another within a DNA strand, and the hydrogen bonds between the base pairs of the two complementary single strands in the double-helix play key roles. Through the different interactions that we have observed the DNA acts to some extent as its own
'/>"/>

Contact: Nina Schwalb
schwalb@phc.uni-kiel.de
49-431-880-2833
Kiel University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Does the desire to consume alcohol and tobacco come from our genetic makeup?
2. Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
3. Many parents at-risk for cancer disclose genetic test results to children
4. Genetics determine optimal drug dose of common anticoagulant
5. Claims of sex-related differences in genetic association studies often not properly validated
6. American College of Medical Genetics responds to new FDA labeling decision for warfarin
7. UNC study questions FDA genetic-screening guidelines for cancer drug
8. Genome study shines light on genetic link to height
9. Selexis Announces Advanced Approach to Maximize Power of Genetic Elements for Rapid Development of High Performance Cell Lines
10. Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring
11. Rutgers Genetics receives $7.8 million for autism research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... such as heart disease, epilepsy and pain, making them ... is still much scientists do not know about the ... into the structure of sodium channels and, specifically, one ... responsible for ,fine-tuning, the activity of the channel. The ... the Journal of Biological Chemistry . , Nerves ...
(Date:4/17/2014)... journal Current Biology on April 17 have ... The Brazilian insects, which represent four distinct but related ... first example of an animal with sex-reversed genitalia. ... different animals, Neotrogla is the only example ... Kazunori Yoshizawa from Hokkaido University in Japan. , During ...
(Date:4/17/2014)... the genetic information of DNA is used to ... numerous different functions in living organisms. Messenger RNA ... expression, by relating the genetic information of DNA ... , By examining the different types and ... at a given time, researchers can determine which ...
Breaking Biology News(10 mins):Structure of sodium channels different than previously believed 2In sex-reversed cave insects, females have the penises 2Rapid and accurate mRNA detection in plant tissues 2
... rapidly read the genomes of entire communities of microbes, ... the jumbled reams of data. In a paper appearing ... headed by researchers at the University of Washington and ... JGI) describes a novel approach for extracting single genomes ...
... LANSING, Mich. Michigan State University scientists, armed with ... Web-based genomic database of information on crops that can ... allow us to create better biofuel crops," said C. ... leader. "Right now, about half of the biofuel crops ...
... In the event of a standoff between the United ... if elected president, know enough about the physics of ... the nation toward reduced greenhouse gas emissions, would John ... America,s carbon footprint? If not, University of California, ...
Cached Biology News:Analysis of Lake Washington microbes shows the power of metagenomic approaches 2Analysis of Lake Washington microbes shows the power of metagenomic approaches 3MSU to create genomic clearinghouse for biofuel crops 2New book tutors future presidents and public on science behind the headlines 2New book tutors future presidents and public on science behind the headlines 3New book tutors future presidents and public on science behind the headlines 4New book tutors future presidents and public on science behind the headlines 5
(Date:1/15/2014)... January 15, 2014 2013 was a ... Brain State Technologies®. They saw continued independent research led ... who were awarded a $1 million grant from the ... “Brain and Behavior” a peer reviewed journal, Amy Grant ...
(Date:1/15/2014)... Jan. 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") ... with R-Pharm, a leading Russian pharmaceutical company, to develop ... Russian Federation , Turkey ... (CIS). Nemonoxacin is a novel antibiotic for the treatment of ...
(Date:1/14/2014)... Diego, CA (PRWEB) January 14, 2014 ... on the products of cells grown under simulated embryonic ... international license agreement with Suneva Medical, Inc. for physician-dispensed ... (CCM). , This agreement is an amendment ...
(Date:1/14/2014)... EquitiesIQ, a leading informational research provider, ... is an emerging biomedical company acquiring, developing, manufacturing, and ... , Free report download: http://equitiesiq.com/reports/alliqua/ , In ... team and Board, which launched the company’s new strategy ...
Breaking Biology Technology:Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 2Histogen and Suneva Medical Expand License for Cell Conditioned Media-based Aesthetic Products Internationally 3EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... , , , , Martin Simon, ... Martin Simon, Petra Albrecht, and Helmut J. Schmidt, University of Kaiserslautern, , ... AG , , Introduction ... the surface , antigen expression of Paramecium primaurelia individual cells ...
... , , , Abstract , ... method that allows researchers to determine , the presence, structure and ... tissue or cell of interest. The basic protocol involves the , ... by amplification of the gene(s) of interest. Due to buffer incompatibilities, , ...
... , Multiporator , , , , , , , ... Protocol No. 4308 915.037 11/1999 , , , ... , Cell line , ... Transfection with , Plasmid pEGFP-N1 (in bidistilled H 2 O), , ...
Cached Biology Technology:Single-cell RT-PCR Analysis of Paramecium Primaurelia with the Eppendorf , cMaster RTplusPCR System 2Single-cell RT-PCR Analysis of Paramecium Primaurelia with the Eppendorf , cMaster RTplusPCR System 3Single-cell RT-PCR Analysis of Paramecium Primaurelia with the Eppendorf , cMaster RTplusPCR System 4Single-cell RT-PCR Analysis of Paramecium Primaurelia with the Eppendorf , cMaster RTplusPCR System 5Single-cell RT-PCR Analysis of Paramecium Primaurelia with the Eppendorf , cMaster RTplusPCR System 6Single-cell RT-PCR Analysis of Paramecium Primaurelia with the Eppendorf , cMaster RTplusPCR System 7cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 2cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 3cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 4cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 5cMaster RTplusPCR System for increased sensitivity and product length , in RT-PCR 6U937 2
... locking design in ice/water bath This ... number, created to easily match Cornings ... yet, please order under the old ... service for assistance. ID clarifier: rack ...
... Yeast Oligo Microarray Kit (V2), 2 ... simultaneously characterize expression of many thousands ... activity during important biological processes. Each ... 6,256 known ORFs from the S288C ...
... Kit (V2), 22K is useful for investigating plant ... microarray contains content derived from the ATH1 v. ... (TIGR) and represents 21,500 genes. ... 3? glass slides each containing an identical 22K ...
... software offers an intuitive, easy-to-use ... control, diverse data handling, and ... Comprehensive functions include data acquisition, ... management in both standalone and ...
Biology Products: