Navigation Links
Can a virtual brain replace lab rats?
Date:2/14/2014

Testing the effects of drugs on a simulated brain could lead to breakthrough treatments for neurological disorders such as Parkinson's, Huntington's and Alzheimer's disease.

Researchers from the University of Waterloo in Canada hope Spaun, the world's largest functioning model of the brain, will be used to test new drugs that lead to medical breakthroughs for brain disorders.

Terrence Stewart, a post-doctoral researcher with the Centre for Theoretical Neuroscience at Waterloo and project manager for Spaun, will tell an audience at the American Association for the Advancement of Science (AAAS) annual meeting in Chicago about the advantages of using whole-brain simulation as a tool to aid new discoveries in medicine.

"Our hope is that you could try out different possible treatments quickly to see how the brain reacts and how each one changes behaviour before testing them in people," said Stewart. "Our brain model offers a new way to test treatments. For Alzheimer's disease or a stroke that causes memory loss, we could see how a new drug affects the firing pattern of individual brain cells and measure how it changes brain performance on memory tests before trying it on people."

Stewart's team has already made progress simulating Parkinson's and Huntington's diseases. Their next step is to simulate Alzheimer's disease after giving Spaun a hippocampus, the brain region involved in forming new memories.

Spaun is more like the human brain than other computer brain models because it makes mistakes and loses abilities in similar ways to people. To simulate the cognitive decline associated with aging, for example, Stewart and his team killed off neurons in the brain model and observed it gradually forgetting more numbers on a memory test.

To reproduce movement problems associated with Huntington's disease and damage to the cerebellum, Stewart damaged parts of the simulated brain affected by those conditions.


'/>"/>
Contact: Nick Manning
nmanning@uwaterloo.ca
226-929-7627
University of Waterloo
Source:Eurekalert

Page: 1 2

Related biology news :

1. Researchers hit virtual heads to make safer games
2. Virtual skin model reveals secrets of skin aging
3. Amazon River exhales virtually all carbon taken up by rain forest
4. Virtual patient advocate delivers preconception care to improve pregnancy outcomes
5. Virtual, squishy creatures evolve to run using evolutionary algorithms
6. Virtual vehicle vibrations
7. UT Dallas researchers pushing the boundaries of virtual reality
8. Virtual women reveal more skin, regardless of body proportions
9. U of M to lead international virtual institute studying climatic and human effects on Earth
10. VirtualScopics Schedules Third Quarter 2012 Earnings Announcement
11. University of Tennessee Space Institute researchers make clinical trials a virtual reality
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)...     Jifflenow ...   Jifflenow, a leading provider ... business-to-business (B2B) events, today announced a partnership with ... communication (NFC), Bluetooth low energy (BLE), and cloud-based ... Jifflenow will integrate its meeting scheduling ...
(Date:12/3/2014)... Ariz. , Dec. 2, 2014 As ... hand readers, Inception Technologies is pleased to announce the ... easier for customers to collect the workforce data that ... problems that have been left by existing readers. Many ... user interface, connectivity and modern technology. Older models force ...
(Date:11/21/2014)... , Nov. 20, 2014   Atmel® Corporation ... in microcontroller (MCU) and touch technology solutions, today launched ... sensors with the widest V cc range ... temperature accuracy and faster I 2 C bus communication ... serial EEPROM memory making them ideal for consumer, industrial, ...
Breaking Biology News(10 mins):Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3Inception Technologies to Release New Biometric Reader 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 4
... running out of room to maneuver. As forests in ... human uses, populations of these arboreal leaf eaters, which depend ... isolated and at risk. But one type of sustainable agriculture, ... critical refuges and bridges between intact forests for the iconic ...
... lives in increasingly humanised landscapes, with limited food resources ... to Spanish researchers, food availability plays a secondary role ... allow wolves to remain in human-dominated environments in Galicia. ... lupus signatus ) varies greatly across the Iberian Peninsula ...
... July 11, 2012 Researchers at the Translational Genomics Research ... could lead to a less costly, less invasive and more ... CKD is a major complication of diabetes, high blood pressure ... is characterized by a progressive deterioration of the kidney,s ability ...
Cached Biology News:Down on the cacao farm: Sloths thrive at chocolate's source 2Down on the cacao farm: Sloths thrive at chocolate's source 3The Iberian wolf lives close to humans more for refuge than for prey 2TGen method isolates biospecimens for treatment of kidney disease 2
(Date:12/19/2014)... EVANSTON, Ill. , Dec. 19, 2014 ... to develop novel drugs for diseases of the central ... Ph.D., president and chief executive officer, will present at ... Dr. Riedel,s presentation will take place at 3:00 p.m. ... St. Francis in San Francisco, Calif. ...
(Date:12/19/2014)... 2014 Research and Markets ( ... "Technology Innovations in Smart Fabrics (Technical Insights)" ... http://photos.prnewswire.com/prnh/20130307/600769 The Research ... a detailed assessment on technological advancements and market ... 1. The Smart Fabrics market is ...
(Date:12/19/2014)... Ed Bilsky, Ph.D., vice president for Research and ... the Neurosciences (CEN), and professor of pharmacology at the ... member of the prestigious Dana Alliance for Brain Initiatives ... receive this honor. , The Dana Alliance ... Foundation. Its mission is to advance public education ...
(Date:12/19/2014)... The empty capsules market is experiencing growth primarily ... innovations in the empty capsules market. The fast-growing ... of the empty capsules market. , Get Full ... Report , The report will enrich both established ... gauge the pulse of the market which in ...
Breaking Biology Technology:Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2Technology Innovations in Smart Fabrics (Technical Insights) 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4
... June 10, 2011 PharmaNet Development Group, Inc. (the "Company" ... tender offer and consent solicitation (the "Offer") for any and ... 2017 (the "Notes"), it has elected to extend the consent ... City time, on June 10, 2011, unless extended or earlier ...
... Professor of Mechanical Engineering at Stevens Institute of ... Specialist Roster as a candidate for grants to ... US Department of State, the Fulbright Specialist Program ... global collaborations that strengthen the positions of US ...
... 2011 The David H. Murdock Research Institute (DHMRI) ... Inc. (ITI) as a next step in the continued ... Research Campus in Kannapolis, NC. Driven by a mission ... for the range of immune-related diseases, the DHMRI provides ...
Cached Biology Technology:PharmaNet Extends Consent Payment Deadline for Notes Tendered in Its Tender Offer and Consent Solicitation 2PharmaNet Extends Consent Payment Deadline for Notes Tendered in Its Tender Offer and Consent Solicitation 3PharmaNet Extends Consent Payment Deadline for Notes Tendered in Its Tender Offer and Consent Solicitation 4Dr. Frank Fisher of Stevens selected for Fulbright specialist roster 2David H. Murdock Research Institute Assumes Control of the Immune Tolerance Institute and Establishes a State of the Art Human Immune Monitoring Laboratory for Biomarker Discovery and Development 2David H. Murdock Research Institute Assumes Control of the Immune Tolerance Institute and Establishes a State of the Art Human Immune Monitoring Laboratory for Biomarker Discovery and Development 3
... Intended for users requiring mass ... AXIMA-LNR linear MALDI TOF Mass spectrometer ... QA/QC applications and for high performance ... oligonucleotide QA/QC, SNP analysis, protein detection, ...
Rat Lung Fibroblasts (RLF) (>500,000 cells)...
... DNA is an ideal small concentrator for ... capable of removing water and organic solvents ... tubes, microplates, vials and round bottom flasks. ... the busy lab. ,The built-in special runs ...
... miVac Duo is suitable for use with ... organic solvents through to water and some ... centrifugal concentrator capable of removing water and ... formats including tubes, microplates, vials and round ...
Biology Products: