Navigation Links
Caltech researchers obtain first brain recordings from behaving fruit flies
Date:2/14/2010

PASADENA, Calif.Researchers at the California Institute of Technology (Caltech) have obtained the first recordings of brain-cell activity in an actively flying fruit fly.

The workby Michael Dickinson, the Esther M. and Abe M. Zarem Professor of Bioengineering, with postdoctoral scholars Gaby Maimon and Andrew Strawsuggests that at least part of the brain of the fruit fly (Drosophila melanogaster) "is in a different and more sensitive state during flight than when the fly is quiescent," Dickinson says.

A paper describing the research appears February 14 in the advance online edition of Nature Neuroscience.

"Prior work on fruit flies has led to many important breakthroughs in biology. For example, the fact that genes reside on chromosomes and our understanding of how genes control development both emerged from experiments on fruit flies," Maimon says. "New research hopes to use these tiny insects to help determine how neurons give rise to complex behavior. This effort is helped by the fact that it is easy to manipulate the genes of fruit flies, but one problem remains: These insects are really, really tiny, which means it is very difficult to record from their brain during active behaviors such as flight."

"Researchers have recorded the neural-cell activity of fruit flies before, but only in restrained preparationsanimals that had been stuck or glued down," Dickinson explains. "Gaby was able to develop a preparation where the animal is tethered"its head clamped into place"but free to flap its wings." By slicing off a patch of the hard cuticle covering the brain, "we were able to target our electrodes onto genetically marked neurons," he says.

A puff of air was used to spur the flies into flapping their wings, while electrodes measured the activity of the marked neurons and high-speed digital cameras simultaneously recorded the flies' behavior.

In particular, the researchers focused on those neur
'/>"/>

Contact: Kathy Svitil
ksvitil@caltech.edu
626-395-8022
California Institute of Technology
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. UNC, Caltech research finds further evidence for genetic contribution to autism
2. Caltech researchers find dual-use sexual attraction and population-control chemicals in nematodes
3. Caltech scientists awarded $20 million to Power the Planet
4. Caltech neurobiologists discover individuals who hear movement
5. Caltech engineers build mini drug-producing biofactories in yeast
6. Caltech researchers awarded $10M for molecular programming project
7. Caltech scientists create DNA tubes with programmable sizes for nanoscale manufacturing
8. Caltech biologists spy on the secret inner life of a cell
9. Caltech scientists engineer supersensitive receptor, gain better understanding of dopamine system
10. Caltech engineers build firast-ever multi-input plug-and-play synthetic RNA device
11. Caltech geobiologists discover unique magnetic death star fossil
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Caltech researchers obtain first brain recordings from behaving fruit flies
(Date:7/9/2014)... fungal pathogens pose a greater threat to biodiversity ... of amphibians, bats, corals, bees and snakes. New ... in the prestigious journal Nature reveals ... to a deadly chytrid fungus implicated in global ... important because it is the basis of vaccination ...
(Date:7/9/2014)... from The Cancer Genome Atlas (TCGA) Research Network ... pathway in lung adenocarcinoma, the most common subtype ... may expand the number of possible therapeutic targets ... number of patients with treatable mutations because many ... exist. , TCGA is jointly funded and managed ...
(Date:7/9/2014)... be able to cope with the rising salinity of Arctic ... today is best known for its tundra and polar bear ... 38 million years ago during what is known as the ... temperate forest with brackish water, home to a variety of ... giant tortoises. Much of what is known about the region ...
Breaking Biology News(10 mins):USF study: Amphibians can acquire resistance to deadly fungus 2Study identifies novel genomic changes in the most common type of lung cancer 2Study identifies novel genomic changes in the most common type of lung cancer 3Shark teeth analysis provides detailed new look at Arctic climate change 2Shark teeth analysis provides detailed new look at Arctic climate change 3
... of the Lawson Health Research Institute and Professor of ... of Medicine & Dentistry at The University of Western ... biology from rebro University in Sweden. Dr. ... and the only recipient this year in the field ...
... of a seething, breathing microbial world. Microorganisms populate every ... of the human skin, to rainforest floors, to hydrothermal ... powerful and pervasive role of microbes in sustaining life, ... is the subject of The Uncharted Microbial World: Microbes ...
... twins are not genetically identical. This surprising finding ... a study being published today in the prestigious journal ... be of great significance for research on hereditary diseases ... How can it be that one identical twin might ...
Cached Biology News:Unexplored microbes hold incredible potential for science and industry 2Unexplored microbes hold incredible potential for science and industry 3
(Date:1/14/2014)... Communications, a leading provider of strategic communications services to corporations and ... the United States and Europe ... JD, is returning to the firm,s Washington, D.C. ... more than two years of service as Associate Commissioner for the ...
(Date:1/14/2014)... BETHESDA, Md. , Jan. 14, 2014  Organovo announced ... from the National Institutes of Health (NIH) to help ... effective treatments to patients on a faster timeline. Organovo ... Sciences (NCATS) and the National Eye Institute (NEI) to ...
(Date:1/14/2014)... MD (PRWEB) January 14, 2014 ... to developing innovative information technology solutions for patients, ... health care stakeholders, announced today the signing of ... US Food and Drug Administration (FDA). This ...
(Date:1/14/2014)... During the 1600’s through the 1800’s doctors contributed unknowingly ... this time period, doctors did not know that they needed ... death of vulnerable patients. In the same way, medical interns ... unwittingly transmitting herpes viruses to their patients. The CBCD explains. ...
Breaking Biology Technology:Former FDA Associate Commissioner Returns To 3D Communications 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
... , LONDON, Sept. 8 ... services to pharmaceutical and biotechnology companies, is pleased to announce ... office. Walter Colasante, as a Vice President, and Sophie ... and reimbursement expertise and expand its current offerings. , ...
... Sept. 8 PDL BioPharma, Inc. (PDL) (Nasdaq: ... ended September 30, 2009 of approximately $71 million, as compared ... revenues are based on second quarter product sales by PDL,s ... by MedImmune. When compared with 2008, royalty revenue for foreign ...
... PAREXEL International Corporation (Nasdaq: PRXL ) announced today it ... Boston, MA. Josef von Rickenbach, Chairman and Chief Executive Officer, ... EDT on Friday, September 11, 2009. , , ... "Upcoming Events" section on PAREXEL,s "Investors" homepage at www.PAREXEL.com ...
Cached Biology Technology:PriceSpective Appoints Colasante as a Vice President and Murdoch as a Director 2PDL BioPharma Provides Third Quarter 2009 Revenue Guidance of Approximately $71 Million 2PDL BioPharma Provides Third Quarter 2009 Revenue Guidance of Approximately $71 Million 3PAREXEL International to Present at Thomas Weisel Partners Healthcare Conference 2
... is a new product number, created ... If showing no availability yet, please ... (E6152) or contact customer service for ... diam. 11.25 6.40 in. ...
... Analysis of large numbers of samples may ... which requires minimum operator attention. System control ... and interface CE 4900. The elegant, powerful ... Windows XP and Windows 98 and 2000., The ...
Mouse monoclonal antibody to QPCT - glutaminyl-peptide cyclotransferase (glutaminyl cyclase)...
... number is a new ... easily match Cornings product ... availability yet, please order ... number (Z35,347-7) or contact ...
Biology Products: