bout fruit-fly embryology, as well. For instance, while scientists had known that the cells in the mesoderm tended to divide twice during gastrulation, they didn't know if this was applicable only to a particular subset of cells, or if it was a hard-and-fast rule. Turns out, it was a rule. "We saw that each and every cell divides twice," says Stathopoulos. "Even more surprising, we saw that the timing of those divisions is based on the cells' original position in the tube--even though, by the time they divide, they've traveled from where they began. They actually remember where they came from."
While Stathopoulos says she's not yet sure what this timed division means, it's a clear sign that there are many more layers of order in embryonic development than had been previously suspected.
"What's fun about this," says Fraser, "is that all the different parts came together at the same time--genetics, labeling, imaging, analysis. It was like a perfect storm . . . in a good way."
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