Navigation Links
Calculating the value of effortful behavior: A clue to schizophrenia-related disability?
Date:7/10/2013

Philadelphia, PA -- Many people with schizophrenia have marked problems with motivation, failing to initiate and persist in goal-directed behavior. These negative symptoms of schizophrenia can be disabling and prevent individuals from realizing their potential.

For many years it was thought this was due to an inability to experience pleasure associated with successful goal attainment. However, recent laboratory studies have shown that hedonic experience is actually intact in people with schizophrenia, calling for new approaches to better understand these motivational deficits.

In a new study published in Biological Psychiatry, Dr. James Gold, at the University of Maryland School of Medicine, and his colleagues now provide a new clue to the relationship between motivational deficits and functional impairment.

They theorized that the lack of motivation may stem from a decreased willingness to expend effort to gain rewards. In other words, individuals with schizophrenia may be less able to properly evaluate future reward in terms of the 'cost' of the effort required.

To test this, the researchers recruited individuals with schizophrenia and a comparison group of healthy individuals. The individuals with schizophrenia were also evaluated for their symptom levels. All participants completed a computerized effort-cost decision-making task in the laboratory. This task required them to make decisions between two alternatives: an easy option with a minimal reward, and a harder option with a higher-value reward.

They found that schizophrenia patients, especially those with prominent negative symptoms, were more likely to choose the less demanding tasks that provided smaller rewards and were less likely than healthy subjects to choose more demanding tasks that offered greater rewards.

"In essence, patients with severe negative symptoms calculate the 'cost' of potential effort versus the value of potenti
'/>"/>

Contact: Rhiannon Bugno
Biol.Psych@utsouthwestern.edu
214-648-0880
Elsevier
Source:Eurekalert

Page: 1 2

Related biology news :

1. Calculating phosphorus and calcium concentrations in meat and bone meal for pig diets
2. When calculating cell-growth thermodynamics, reconsider using the Gibbs free energy equation
3. Medical device, health professionals attend first national conference on value-driven engineering
4. Womens scientific achievements often overlooked and undervalued
5. Boston Healthcare Associates Roundtable Explores Challenges and Opportunities Surrounding the Value of Big Data within the Life Sciences
6. Family values
7. Reproducibility Initiative to increase the value of biomedical research
8. Cross Match Technologies Undoubtedly Offers the Highest Value to Customers in the North American Biometrics Market, Says Frost & Sullivan
9. Is the detection of early markers of Epstein Barr virus of diagnostic value?
10. Study confirms prognostic value of new IASLC/ATS/ERS adenocarcinoma sub-classification
11. Controversial dam removals founded on value conflicts
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 13, 2015 /PRNewswire/ - Today, FindBiometrics, the leading source of biometrics ... its new website design. "When we launched FindBiometrics ... Peter O,Neill , founder and CEO of FindBiometrics. "Now ... involvement from the key players on a very broad scale.  ...
(Date:1/22/2015)... 20, 2015 NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) ... on the recent success of the Wocket™ smart wallet at CES 2015 ... wallet was named as one of the "11 Hot Products at CES" ... Launched At CES So Far" by Newseveryday.com and "The top 10 gadgets ...
(Date:1/22/2015)... YORK , Jan. 22, 2015   EyeLock, Inc. , ... it has appointed Steve Gerber to the new ... will be responsible for leading development of mobile platforms and ... years of success and innovation in the semiconductor industry to ...
Breaking Biology News(10 mins):Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... scientists believe an Oregon State University graduate student ... Pacific Southwest Research station on the Tahoe National ... presence has not been confirmed in California since ... was conducting research on another carnivore called the ...
... Friday, March 7, 2008) New research from ... American diet of eating lots of meat and not much ... pose a risk to infant neurological development. Omega-3 fatty acids ... and herring and in smaller amounts in eggs and chicken. ...
... - A newly defined biochemical pathway in plants may ... yield larger quantities of alternative transportation fuels than currently ... The pathway moves materials that determine cell shape and ... Szymanski, a plant geneticist and cellular biologist. By learning ...
Cached Biology News:Scientists believe photograph depicts wolverine in California 2Typical North American diet is deficient in omega-3 fatty acids 2Newly defined signaling pathway could mean better biofuel sources 2Newly defined signaling pathway could mean better biofuel sources 3Newly defined signaling pathway could mean better biofuel sources 4
(Date:1/22/2015)... (PRWEB) January 22, 2015 GEA Niro ... table top laboratory homogenizer, the PandaPLUS 2000, which is ... nanoemulsions , and cell disruption . This compact ... products, fruit juices, liquid food, food additives and ingredients ...
(Date:1/22/2015)... Crystal Diagnostics (CDx) Xpress System, a rapid ... AOAC-PTM Certifications for the six non-O157 Shiga toxin-producing E. coli ... to as STEC or the “Big-6”) as well as Escherichia ... per 325 g of raw ground beef and raw beef ...
(Date:1/22/2015)... Geneva, Switzerland (PRWEB) January 22, 2015 ... for characterized mammalian Research Cell Banks (RCBs) used for ... generated Research Cell Banks will include Next-Generation Sequencing ... cell’s genetic architecture de-risks biologic manufacturing by ensuring the ...
(Date:1/22/2015)... Jan. 22, 2015   GenoSpace , a precision medicine software ... enable the broad use of genomic, imaging and other biomedical ... of Michelle Munson , CEO of Aspera, an IBM ... Logo - http://photos.prnewswire.com/prnh/20150122/170713 "We are ...
Breaking Biology Technology:GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2GenoSpace Expands Board with Appointment of Michelle Munson 2
... biometrics company enabling applications for the real ... with Methode Electronics, Inc. One of the ... being a solid Tier 1 automotive supplier ... devices. Together, Methode and Lumidigm will bring ...
... ... alternatives, WALTHAM, Mass., Aug. 5 ... Company is focusing its,day-to-day operations exclusively on obtaining financing or consummating ... Company,s employees were released from employment, except,for Shawn Cain, the Company,s ...
... to Curb Unsafe Sex and Drug, Use ... Response, MEXICO CITY, Aug. 5 In a ... calls on global leaders to aggressively,expand HIV prevention programs ... use. Citing hundreds of clinical trials and,observational studies, the ...
Cached Biology Technology: Lumidigm Signs Strategic Agreement with Methode Electronics : Automotive Supplier Invests in Biometric Component Development 2Arbios Announces It Has Suspended Operations 2Arbios Announces It Has Suspended Operations 3Arbios Announces It Has Suspended Operations 4Arbios Announces It Has Suspended Operations 5Leading AIDS Experts Urge Greater Focus on Behavior-Change Programs to Prevent HIV 2Leading AIDS Experts Urge Greater Focus on Behavior-Change Programs to Prevent HIV 3Leading AIDS Experts Urge Greater Focus on Behavior-Change Programs to Prevent HIV 4
Geneticin Selective Antibiotic liquid...
Immunogen: Extract of pigmented melanoma metastases from lymph nodes. Storage: -20 C, Avoid Freeze/Thaw Cycles...
alpha N-catenin (C-19)...
... Clone/PAD: ZMD.257. Immunogen: Synthetic peptide ... the human Connexin 36 protein This ... used to generate another Zymed polyclonal Connexin ... Reacts with mouse Connexin 36. Reactivity: ...
Biology Products: