Navigation Links
CWRU dental researchers discover human beta defensins-3 ignite in oral cancer growth
Date:7/13/2010

tion its role on tumor growth and found it attracts other molecules that actually help the cancerous tumor grow and eventually spread to other parts of the body.

It appears hBD-3 plays a role in the development of the chemokine receptor called CCR2 that recruits tumor-associated macrophage cells to infiltrate the tumor site and stimulate tumor growth. The tumor-associated macrophages and other molecules release growth factors that encourage the progression of the tumor. Eventually tumor cells break away, travel and spread the cancer to other places in the body.

"This is the first time that we have evidence that CCR2, too, has a role in oral cancer growth," said Jin.

The researcher plans to continue studying the role of hBDs in oral health and to develop diagnostic tools that use the biomarker to detect early cancer.


'/>"/>

Contact: Susan Griffith
susan.griffith@case.edu
216-368-1004
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
2. Eastman Dental Center awarded $1.6 million to find ways to prevent cavities
3. New generation of orthopedic, dental and cardiovascular prostheses
4. Smart coating opens door to safer hip, knee and dental implants
5. University of Plymouth invests in dental research
6. Accidental discovery produces durable new blue pigment for multiple applications
7. Dental delight: Tooth of sea urchin shows formation of biominerals
8. Cleveland Clinic, CWRU dental researcher finds switch that turns on the spread of cancer
9. How can accidental captures of loggerhead turtles be reduced?
10. Military application of Transcendental Meditation gaining acceptance
11. Pitt Dental School researchers find susceptibility for caries, gum disease in genes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... cities in New Mexico, nearly every public golf course ... precious potable water supplies. Across the U.S. Southwest as ... receive treated effluent. Reusing the effluent increases the sustainability ... homeowners alike fertilize their lawns during the growing season. ... Mexico State University turfgrass expert has a new vision ...
(Date:7/10/2014)... July 2, 2014  Unisys Corporation,s (NYSE: UIS ... Nederland N.V., today announced that it has been selected by ... manage a new Basic Provision Biometrics solution for penitentiaries across ... won the contract with a solution based on its open ... term of the contract is up to seven years, with ...
(Date:7/10/2014)... GOTHENBURG, Sweden , July 7, 2014 ... won its first major design win (DW). A Chinese Top ... with the planned start of mass production in October 2014. ... with a Chinese Top 5 smartphone OEM, which has a ... 2014 and a target sales volume for this phone of ...
Breaking Biology News(10 mins):'Tailored' water -- the latest in lawn care 2Unisys Delivers New Basic Provision Biometrics Solution to Dutch Custodial Institutions Service 2Unisys Delivers New Basic Provision Biometrics Solution to Dutch Custodial Institutions Service 3FPC Wins DW for 1021 Touch Sensor for Flagship Smartphone from Chinese Top 5 Smartphone OEM 2
... working with collaborators in Germany, France and Korea have ... of twisting or torque in a metallic nanowire. This ... enable measurements of the untwisting of DNA and have ... Spin-induced torque is central to understanding experiments, from ...
... CINCINNATI Two proteins interact in a previously unknown ... studies looking for the causes of defective organs in ... at Cincinnati Children,s Hospital Medical Center. Reporting their ... , the researchers said the mechanism coordinates cell identity ...
... inventors designing and manufacturing biomedical sensors, healthcare and its ... Come learn what to expect from this new and ... free seminar set for Nov. 6, 2008, from 4:45-6 ... Engineering (ECE) Building, 141 Warren St, at the northwest ...
Cached Biology News:Detecting tiny twists with a nanomachine 2New regulatory mechanism discovered for cell identify and behavior in forming organs 2New regulatory mechanism discovered for cell identify and behavior in forming organs 3NJIT seminar set for Nov. 6 to focus on bioelectronics -- emerging research area 2
(Date:7/11/2014)... MISSISSAUGA, ON , July 11, 2014 /CNW/ - ... Canada approved APTIOM TM (eslicarbazepine acetate) for use ... partial-onset seizures in patients with epilepsy who are not ... not indicated for use in patients under 18 years ... the most common neurological disorders and according to Epilepsy ...
(Date:7/10/2014)... 2014 Women in the West ... an additional family planning option. Sayana® Press has ... all levels of the health system and in ... widely used contraceptive—Pfizer’s Depo-Provera® (depot medroxyprogesterone acetate)—with the ... the first of four African countries expected to ...
(Date:7/10/2014)... Understanding the need for better quality and higher ... that currently exists in this area, ChanTest has recently ... validated ion channel and GPCR cell lines. ChanTest’s ... channels control many critical physiological functions throughout the body. ... to treat a variety of human diseases. , ...
(Date:7/10/2014)... Robert Harman, DVM, Founder and CEO of Vet-Stem, Inc., ... the relaunch of his highly informative blog, now named Stem ... What are Stem Cells ?” Dr. Harman’s purpose for ... the basics of stem cell therapy so that pet owners ... treatment when considering regenerative medicine. , A veterinarian by trade, ...
Breaking Biology Technology:Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 2Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 3Sunovion Pharmaceuticals Canada Inc. Announces Health Canada Approval of APTIOM(TM) (eslicarbazepine acetate) as a Once-Daily Adjunctive Treatment for Partial-Onset Seizures in Patients with Epilepsy 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 2Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 3Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 4Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 5Injectable Contraceptive Launched in Burkina Faso to Expand Choice and Address Unmet Need 6Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 2Leader in Ion Channel Research Announces Newly Validated and Re-Engineered Cells 3Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3
... to build a business from scratch and sell it for a ... we wanted to speed it up so the entire thing from ... , ,In a few rare cases, thats exactly what happened for ... what my father had told me for years: Patience is a ...
... A Wisconsin Company that manufactures a state-of-the-art homeland ... the top 100 technological innovations of 2003 ... of What's New Awards honored Oshkosh Truck Corporations ... in the Engineering category, describing the new command-and-communications vehicle ...
... to write about weblogs - until now. Truth be told - ... much for bandwagons. If everyone is going right, I'll move left ... first take on blogging was that it was just another technology-enabled ... that any other fool could read it. Of course, there was, ...
Cached Biology Technology:An Overnight Business Success Takes 20 Years 2An Overnight Business Success Takes 20 Years 3Oshkoshs Pierce Security Vehicle Ranked in top 100 Technological Innovations for 2003 2The Blog Nation 2The Blog Nation 3
Request Info...
...
Mouse GM CSF Construction Kit provides antigen affinity purified polyclonal capture and tracer antibodies, and antigen standard for development of approximately ten microplate assays....
... Inventory Storage Racks for Standard 3" ... fit all makes and models of ... of high quality stainless steel and ... stainless steel or plastic boxes. ...
Biology Products: