Navigation Links
CWRU School of Medicine has evidence vaccine against malaria will reduce disease
Date:12/20/2007

CLEVELAND December 20, 2007 Researchers at the Case Western Reserve University School of Medicines Center for Global Health & Diseases published data potentially impacting the three billion people exposed to malaria every year. Brian T. Grimberg, Ph.D., Peter A. Zimmerman, Ph. D., and Christopher L. King, M.D., Ph.D. published in the December issue of Public Library of Science Medicine (PLoS Medicine), novel findings proving new antibodies inhibit infection by the Plasmodium vivax (P. vivax) malaria parasite. The research suggests a Duffy binding protein-based vaccine could provide protection against malaria blood-stage infection. This specific protein is an attractive candidate for a P. vivax vaccine, as it could decrease illness in malaria prevalent regions. For the first time, scientists from the eight partner institutions along with the Center for Global Health & Diseases, conclusively proved that invasion of human red blood cells by the malaria parasite could be prevented by these antibodies.

Unlike other types of malaria, a P. vivax infection relies solely upon the single molecular interaction between the Duffy antigen on human red blood cells and the Duffy binding protein expressed by the parasite to establish the disease. By interrupting the interaction of parasite binding to the red cell, the researchers and their colleagues around the United States and in Papua New Guinea, India, and Thailand, have the potential to eliminate P. vivax malaria. By exploiting this required interaction, the research offers a clear path toward development of a P. vivax malaria vaccine.

James W. Kazura, M.D., Director of the Center for Global Health and Diseases at Case Western Reserve University emphasized P. vivax is widely distributed throughout Asia, the South Pacific, parts of Africa, and South America. However, the importance of developing a P. vivax vaccine to the American public is underscored by the fact that this is the form of malaria most fr
'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. Rutgers high school outreach gets $3 million boost from NSF
3. UGA Odum School of Ecology professor receives grant to study West Nile Virus in NYC
4. Folic acid lowers blood arsenic levels, according to Mailman School of Public Health study
5. UMass Medical School researchers receive $8.5M grant award to fight AIDS
6. Asthma link to post-traumatic stress disorder, says Mailman School of Public Health study
7. Kids eat more fruits, vegetables when schools offer salad bar
8. New research seeks to enhance quality and security of wireless telemedicine
9. Penn Veterinary Medicine report new strategy to create genetically-modified animals
10. SNM applauds NAS study showing need to restore federal nuclear medicine research funding
11. Gene-targeting pioneer Mario Capecchi shares 2007 Nobel Prize in Medicine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... under the normal circumstances, astrocytes participate in ... environment, and exhibit therapeutic and repairing effects ... studies have found that nerve cells differentiated ... have reduced viability, which produces influences on ... Kailuan General Hospital, Hebei United University, China ...
(Date:7/11/2014)... July 11, 2014 Research and Markets ... Biometrics Technology Market - Industry Analysis Size Share Growth ... offering. http://photos.prnewswire.com/prnh/20130307/600769 ... has created a need for high level security in ... personnel authentication such as username and passwords, tokens etc. ...
(Date:7/11/2014)... Rio de Janeiro, Brazil- In the brains of ... mechanism that allows an electric or chemical signal ... another. Chemical synapses, which are the most abundant ... inhibitory. Synapse formation is crucial for learning, memory, ... and inhibitory synapses critical for brain function. ...
Breaking Biology News(10 mins):International Biometrics Technology Market - Industry Analysis Size Share Growth Trends and Forecast to 2019 2Blame it on the astrocytes 2
... number one killer in the world and India carries more ... set to rise: it is predicted that by 2010 India,s ... Today, an international team of 25 scientists from four countries ... the world,s population carries a mutation almost guaranteed to lead ...
... of yeast cells has resulted in the most detailed ... a Texas A&M University chemical engineering professor whose findings ... until now have remained mostly theory., Working with populations ... Katy Kao, assistant professor in the Artie McFerrin Department ...
... new, international competition called the Digging into Data ... the Joint Information Systems Committee (JISC) from the ... (NEH) and the National Science Foundation (NSF) from ... Humanities Research Council (SSHRC) from Canada. ...
Cached Biology News:The heart disease mutation carried by 60 million 2Evolutionary process more detailed than previously believed, study shows 2Evolutionary process more detailed than previously believed, study shows 3Evolutionary process more detailed than previously believed, study shows 4Leading research agencies announce new international competition: "The digging into data challenge" 2
(Date:7/10/2014)... 2014 Deep Knowledge Ventures last ... on ‘Commercialising Longevity Research’ and welcomed a host ... London Bioscience Innovation Center for the event, organised ... Analytics Ltd. The meeting highlighted the need for ... for age-related disease, as well as the crucial ...
(Date:7/10/2014)... OMICS Group’s 5th International conference and ... 2014 at Double Tree by Hilton Beijing, China is ... Analytical & Bioanalytical research methods only to facilitate improved ... occasion, Dr. Srinubabu Gedela, MD of OMICS Group Inc ... remarkable one in bringing a unique and international mix ...
(Date:7/10/2014)... Capital, a firm specializing in acquiring and managing food ... the Slim-Fast brand from Unilever. Unilever will retain a ... were not disclosed. Slim-Fast is a branded ... shakes, powders, bars and snacks to retail customers throughout ... United Kingdom and Ireland.  The ...
(Date:7/10/2014)... help in the fight against terrorism with the creation ... explosives with the use of light and special glass ... Actuators B: Chemical , the researchers describe a novel ... as low as 6.3 ppm (parts per million). It ... , "Traditionally explosives detection has involved looking for metals ...
Breaking Biology Technology:DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 2DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 3DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 4DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 5DKV Sponsors Forum on Commercialising Longevity Research; Brings Together Scientists, Investors, Entrepreneurs and Celebrities 6A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4Kainos Capital Acquires Slim-Fast From Unilever 2Detecting trace amounts of explosives with light 2
... Corp. said it has bought all outstanding stock ... handles bank transactions and check image processing. , ,Metavante, ... said in October that it would buy VectorSGIs stock ... wholly owned subsidiary. The move followed Metavantes acquisition of ...
... Jim Doyle, right, is joined by Commerce Sec. Cory ... Wis. Wisconsins Department of Commerce will fund ... and other assistance at centers around the state, Governor ... provide $1 million per year for five years, he ...
... U.S. Supreme Court made a patent-law decision on Monday that ... sector. , ,The court denied an appeal in Univ. ... solidifies the decision that was made by the U.S. Court ... patent because the inventor did not provide an adequate written ...
Cached Biology Technology:State and university form network for entrepreneurial outreach 2State and university form network for entrepreneurial outreach 3Describe your invention, or your biotech patent may be worthless 2Describe your invention, or your biotech patent may be worthless 3Describe your invention, or your biotech patent may be worthless 4Describe your invention, or your biotech patent may be worthless 5
... gun low-pressure system, 220-240 V, is used for ... handheld device employs an adjustable helium pulse to ... from the inner wall of a small plastic ... be used for in situ, in vitro, in ...
... Hybridization Wash Pack provides optimized blocking ... Preparation Quality Clarifier: Ready-to-use wash solutions ... SigmaScreen(tm) APS Coated Slides for Microarrays ... Hybridization Blocking Buffer: 1L • Microarray ...
Mouse polyclonal antibody raised against a partial recombinant MHC2TA. NCBI Entrez Gene ID = 4261...
Mouse monoclonal antibody raised against a partial recombinant JRKL. NCBI Entrez Gene ID = JRKL...
Biology Products: