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CU researchers develop new software to advance brain image research
Date:6/27/2011

A University of Colorado Boulder research team has developed a new software program allowing neuroscientists to produce single brain images pulled from hundreds of individual studies, trimming weeks and even months from what can be a tedious, time-consuming research process.

The development of noninvasive neuroimaging techniques such as functional magnetic resonance imaging, or fMRI, spurred a huge amount of scientific research and led to substantial advances in the understanding of the human brain and cognitive function. However, instead of having too little data, researchers are besieged with too much, according to Tal Yarkoni, a postdoctoral fellow in CU-Boulder's psychology and neuroscience department.

The new software developed by Yarkoni and his colleagues can be programmed to comb scientific literature for published articles relevant to a particular topic, and then to extract all of the brain scan images from those articles. Using a statistical process called "meta-analysis," researchers are then able to produce a consensus "brain activation image" reflecting hundreds of studies at a time.

"Because the new approach is entirely automated, it can analyze hundreds of different experimental tasks or mental states nearly instantaneously instead of requiring researchers to spend weeks or months conducting just one analysis," said Yarkoni.

Yarkoni is the lead author on a paper introducing the new approach to analyzing brain imaging data that appears in the June 26 edition of the journal Nature Methods. Russell Poldrack of the University of Texas at Austin, Thomas Nichols of the University of Warwick in England, David Van Essen of Washington University in St. Louis and Tor Wager of CU-Boulder contributed to the paper.

Brain scanning techniques such as fMRI have revolutionized scientists' understanding of the human mind by allowing researchers to peer deep into people's brains as they engage in mental activi
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Contact: Tal Yarkoni
tal.yarkoni@colorado.edu
303-492-4299
University of Colorado at Boulder
Source:Eurekalert

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