Navigation Links
CU-Boulder technology used to identify unexpected bacteria in cystic fibrosis patients
Date:12/3/2007

Molecular technology developed by a University of Colorado at Boulder professor to probe extreme life forms in undersea hydrothermal vents has been used to identify unexpected bacteria strains in the lung fluid of Denver children suffering from cystic fibrosis, findings that may lead to more effective therapies.

Instead of standard culturing techniques, researchers used nucleic acid gene sequencing to rapidly detect, identify and classify pathogens found in the lungs of cystic fibrosis sufferers, said CU-Boulder Professor Norman Pace, who pioneered the method in the 1990s using microbes from Pacific Ocean hydrothermal vents. Pace and his colleagues at CU-Denver's Health Sciences Center and Denver's Children's Hospital identified more than 60 species of bacteria in samples of 28 cystic fibrosis patients in Denver. Thirteen samples contained bacteria that are not routinely assessed by culturing.

The presence of the unexpected bacteria may help explain cases of unidentified lung inflammation and the consequent failure of patients -- primarily children -- to respond to standard treatments, said Pace. "The results show molecular sequencing is a more effective, faster and far less expensive way to assess airway bacteria than routine clinical cultures and better identifies targets for further clinical evaluation," said Pace.

Cystic fibrosis, a life-threatening genetic disease affecting about 30,000 people in the United States, is marked by a build-up of mucus in the lungs and pancreas that can clog organs, according to the Cystic Fibrosis Foundation. In addition to causing difficulty breathing, the thick mucus acts as a breeding ground for bacteria in the lungs that causes swelling, inflammation and infections that can lead to lung damage. Most deaths from cystic fibrosis are caused by such infections, said Pace.

A paper on the subject was published the week of Dec. 3 in the Proceedings of the National Academy of Sciences. Co-
'/>"/>

Contact: Norman Pace
norman.pace@colorado.edu
303-735-1808
University of Colorado at Boulder
Source:Eurekalert

Page: 1 2

Related biology news :

1. CU-Boulder team discovers first ancient manioc fields in Americas
2. Nutrient pollution drives frog deformities by ramping up infections, says CU-Boulder study
3. CU-Boulder worm study sheds light on human aging, inherited diseases
4. Yale scientists use nanotechnology to fight E. coli
5. Voice Biometrics Gains Traction as Most Accurate and Convenient Technology to Secure Customer Privacy
6. M2SYS Partners with SecuGen Corporation to Support Market Leading Hamster Plus Fingerprint Reader with Auto-On Technology
7. Silicon Valley Technology Leaders LaserCard Corporation and Tesla Motors Sign LaserPass Secure Access Deal
8. Nanotechnology: Whats that?
9. UCs NIH grant brings technology from outer space to playgrounds
10. BIO-key(R) International to Showcase Deployed Biometric Security Applications at 2007 Biometric Technology Expo
11. Cogent Systems and Northrop Grumman Reach Agreement to Settle Automated Fingerprint Identification Technology Suit and Create Strategic Alliance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/10/2015)... Fingerprint Cards (FPC) has received an order for ... World Peace Industrial Group (WPI), part of WPG Holdings. WPI ... . Deliveries are planned to take place during Q3 2015 ... China . The order value of 235 ... 1 000 MSEK for 2015.   Jörgen Lantto, acting ...
(Date:5/5/2015)... 2015, NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... growing mobile commerce market, reminds investors and media that  Mr. ... presenting  at CARTES SECURE CONNEXIONS AMERICA 2015, held in ... The three-day conference is organized into a series of ... themed Global Fraud: Where is the Trust in Cyberspace? ...
(Date:4/21/2015)... 2015 High crime rate, ... boosting access control systems market in Saudi ... recently published report by TechSci Research " Saudi Arabia Access ... control systems market in Saudi Arabia ... access control systems market in the Kingdom is growing ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 235 Million 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3
... energy challenges facing our nation and designing a path ... challenges will be the focus of the 2012 Public ... national conference takes place April 29-May 1 at Ohio ... in partnership with the Association of Public and Land-grant ...
... with cat scratch fever and transmitted predominately by fleas may ... arthritis, according to new research from North Carolina State University. ... in nature by fleas, ticks and other biting insects. It ... well as by bites or scratches from infected cats and ...
... developed, researchers at Carnegie Mellon University have discovered how ... their coordinated assault on invading pathogens. The immune cells, ... other therapeutics used to amplify the immune system. The ... Angewandte Chemie , marks the first time that scientists ...
Cached Biology News:Bartonella infection associated with rheumatoid illnesses in humans 2Carnegie Mellon fluorescent biosensor reveals mechanism critical to immune system amplification 2
(Date:5/26/2015)... May 26, 2015 Pharmaco-Kinesis Corporation (PKC) announced ... convened at Shutters on the Beach in ... status of the Company,s innovative Metronomic Biofeedback Pump (MBP), ... deliver chemotherapy over time to a target site of ... and biofeedback system in real-time.  ...
(Date:5/26/2015)... mája 2015 Kevin Xu , ... prezidentom Barackovi Obamovi a Billovi Clintonovi za ich ... Dr. Rongxiang Xu , otca Kevina. ... Dr. Xu bol pionier, inovátor, humanitárny pracovník ... v oblasti vedy a príkladné vedenie svojej komunity ...
(Date:5/26/2015)... MENLO PARK, Calif. , May 26, 2015 /PRNewswire/ ... focused on the emerging field of regenerative medicine, today ... issued in June 2014 were exercised prior to their ... to the Company of $11.7 million. "We ... Pedro Lichtinger , President and CEO of Asterias. "This ...
(Date:5/26/2015)... , May 26, 2015 /PRNewswire/ - Fluorinov Pharma ... of Luke M. Beshar to its Board ... financial and pharmaceutical industry expertise as Fluorinov accelerates its ... the Fluorinov team, it is a pleasure to welcome ... a significant impact on the strategy, financial strength and ...
Breaking Biology Technology:Pharmaco-Kinesis Corporation Convenes Third Neuro-Oncology Clinical Advisory Board Meeting 2Pharmaco-Kinesis Corporation Convenes Third Neuro-Oncology Clinical Advisory Board Meeting 3Pharmaco-Kinesis Corporation Convenes Third Neuro-Oncology Clinical Advisory Board Meeting 4Pharmaco-Kinesis Corporation Convenes Third Neuro-Oncology Clinical Advisory Board Meeting 5Dr. Rongxiang Xu, O legende 2Asterias Biotherapeutics Receives $11.7 Million in Proceeds from Exercise of Warrants 2Asterias Biotherapeutics Receives $11.7 Million in Proceeds from Exercise of Warrants 3Luke M. Beshar Appointed to Fluorinov Pharma Board of Directors 2Luke M. Beshar Appointed to Fluorinov Pharma Board of Directors 3
... Genzyme Corp. said on Wednesday it has agreed ... Wisconsin-Madison biotech spinoff, for $600 million in cash. , ,Bone ... more than $2 billion and almost 7,000 employees worldwide, plan ... companies recently reported healthy quarterly profits and revenues. Bone Care ...
... a new copy machine for $57,000. , ,The Z-Corp ... typical office copier: It makes three-dimensional models of small structures ... , ,Using white polymer powder and colored inks, the printer ... a time. Z-Corp is headquartered in Burlington, Massachusetts. , , ...
... can submit executive summaries of their businesses for angel ... May 9. , ,The Wisconsin Angel Network ... investor networks with entrepreneurs based on the investors' market ... a deal-flow pipeline, has been designed to be a ...
Cached Biology Technology:Massachusetts firm to buy UW spinoff Bone Care for $600 million 2Massachusetts firm to buy UW spinoff Bone Care for $600 million 3Start-ups, angels can connect on new state Web site 2Start-ups, angels can connect on new state Web site 3
Nuclear/Cytosol Fractionation Kit Research Focus: other Storage Temperature: 4C Shipping Temperature: 4C...
Cytosol/Particulate Rapid Separation Kit Research Focus: other Storage Temperature: -20C Shipping Temperature: 4C...
Request Info...
Purified anti-human CD182 (CXCR2)...
Biology Products: