Navigation Links
CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics
Date:8/25/2008

ardiomyopathy, or HCM, a genetic disease marked by a thickening of heart muscle related to a weakness in individual muscle fibers that causes them to work harder to pump blood and consequently enlarge. HCM occurs in one in 500 people in the United States and is the most common cardiac cause of sudden death in young athletes. About 20 genes associated with HCM have been identified and others are being investigated, she said.

In 2006 Leinwand was named a Howard Hughes Medical Institute Professor, one of 20 faculty nationwide to receive a four-year, $1 million undergraduate education award from the Howard Hughes Medical Institute in Chevy Chase, Md. As part of her successful proposal to enhance science education at CU-Boulder, she initiated an undergraduate laboratory research program known as the Python Project.

In the past two years, CU-Boulder undergraduates working with Leinwand have been studying the genome of the Burmese python, searching out and analyzing particular genes they suspect may be involved in the rapid heart muscle changes.

"Pythons can eat up to 100 percent of their body weight at one sitting, so they have to be able to respond metabolically in a dramatic way," said Leinwand. In addition to the eye-popping changes in heart muscle and metabolism, the python's insulin levels go up 40-fold and their triglycerides rise by more than 100-fold following substantial meals, changes that would "kill a human," she said.

Pythons also exhibit very little muscle loss when at rest, which is of interest to researchers studying diseases like AIDS and cancer and the inevitable process of aging. "We think several of the striking changes we see in python physiology may have significant potential for the pharmaceutical industry," she said.

Hiberna -- which received a $100,000 proof-of-concept investment from CU's Technology Transfer Office to help support the development of the new technology -- has started sequencing the
'/>"/>

Contact: Leslie Leinwand
Leslie.Leinwand@colorado.edu
303-492-7606
University of Colorado at Boulder
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. How the public perceives biotech
2. Monsanto expands sponsorship for Peking-Yale Joint Agrobiotechnology Center
3. Biotech Co. founded by UCLA Scientists to be acquired by Astellas, Pharma Inc.
4. Workshops on biotechnology and water for science journalists
5. Oncolytics Biotech, Inc. announces publication of research
6. Genetic Engineering & Biotechnology News reports on advances in miRNA
7. Biotechnology needs 21st century patent system: Expert
8. Genetic Engineering & Biotechnology News reports on cancer biomarkers
9. Food biotechnology: real world challenges
10. Genetic Engineering & Biotechnology News reports on growing use of cell-based assays
11. Biotechnology key to developing sustainable industries says international panel
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics
(Date:7/8/2015)... , July 8, 2015 The ... as this summer,s must have products such as wearables, smart ... as popularity for biometrics based devices continues to rapidly grow.  ... Inc. (NASDAQ: NXTD ), Google Inc. (NASDAQ: GOOG ... FIT ), GoPro, Inc. (NASDAQ: GPRO ) and ...
(Date:7/7/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... commerce market announces a revised version of one of its first ... air on CNBC in New York , ... San Francisco metro areas.    ... ability to replace all the cards in your wallet and keep ...
(Date:7/2/2015)... Fingerprint Cards has received an order for its ... distributor World Peace Industrial Group (WPI), part of WPG Holdings. ... . Deliveries are planned to take place during Q3 ... manufacturers in Asia . The order value ... of approximately 2,200 MSEK for 2015. Jörgen Lantto, ...
Breaking Biology News(10 mins):Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 2Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 4Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 5Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 6Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 2Wocket Smart Wallet Commercials Airing on CNBC to Showcase This Summer's Must- Have Tech Product 3FPC Receives Order for Touch Fingerprint Sensors of 268 MSEK 2
... levels of carbon dioxide in the atmosphere are a ... The lack of atmospheric carbon dioxide (CO 2 ) ... their aquatic relatives, microalgae. For plants and microalgae, ... their photosynthesis process that, along with sunlight, manufactures sugars ...
... University of Wisconsin, USA, report in the journal ... human embryonic stem cells of a type of cell ... new possibilities for both basic and clinical research. ... are responsible for making myelin in the central nervous ...
... America,s biological field stations have long been home to ... them important places for serendipitous discoveries in the biological ... the April issue of the journal BioScience , ... Term Ecological Research (LTER) Network and other groups state ...
Cached Biology News:ISU researcher identifies protein that concentrates carbon dioxide in algae 2Human ES cells progress slowly in myelin's direction 2Field stations foster serendipitous discoveries in environmental, biological sciences 2Field stations foster serendipitous discoveries in environmental, biological sciences 3
(Date:8/4/2015)... (PRWEB) , ... August 04, 2015 , ... ... rapid point-of-care (POC) diagnostic tests – today announced that Robert A. Gregg, PhD, ... Gregg has more than 30 years of relevant experience and remarkable achievements in ...
(Date:8/4/2015)... , Aug. 4, 2015   California Cryobank Stem ... acquisition of LifeLine Cryogenics, an east coast cord blood ... New York tristate area. LifeLine clients will ... prepaid contracts will be honored. Since 1991, ... offering storage of sperm, eggs, embryos, and cord blood ...
(Date:8/3/2015)... Aug. 3, 2015  MiMedx Group, Inc. (NASDAQ: ... amniotic tissue and patent-protected processes to develop and market ... Orthopedic, Spine, Sports Medicine, Ophthalmic and Dental sectors of ... 35 th Annual Canaccord|Genuity Growth Conference in ... Chairman and CEO, William C. Taylor , President ...
(Date:8/3/2015)... August 3, 2015 E-QURE Corp. ... of its Bio-electrical Signal Therapy device ("BST Device"), a ... hard to heal chronic wounds, today announced that the ... an Israeli distributor specializing in medical devices, for the ... Chemipal is a 70 years old, sales, marketing and ...
Breaking Biology Technology:RPS Diagnostics Welcomes Robert Gregg as Senior Vice President of Clinical and Regulatory Affairs 2RPS Diagnostics Welcomes Robert Gregg as Senior Vice President of Clinical and Regulatory Affairs 3FamilyCord Announces Acquisition of LifeLine Cryogenics 2MiMedx To Present At 35th Annual Canaccord|Genuity Growth Conference 2E-QURE Corp Signs Second Distribution Agreement in Israel 2E-QURE Corp Signs Second Distribution Agreement in Israel 3
... 11, 2011 /PRNewswire-Asia/ -- Chinmax Medical Systems Inc., a ... regarding the progress of its lawsuit against Inverness Medical ... According to the Complaint, Inverness Medical Beijing ... the same to Chinmax customers during the period when ...
... SAN DIEGO, April 11, 2011 MabVax Therapeutics, Inc., ... the development of vaccine and antibody based therapies to ... announces that it has received the Phase 2 portion ... the National Cancer Institute (NCI) under the agency,s Streamlined ...
... VIGILAIR Systems, an industry leader in Ultraviolet Germicidal ... and first of its kind hospital study that demonstrated ... with the application of VIGILAIR® air cleaning technology in ... published article , Effect of enhanced ultraviolet germicidal irradiation ...
Cached Biology Technology:Beijing Chaoyang District Court Grants Investigation Letters Against Inverness Medical Beijing, A Subsidiary of Alere Inc. 2MabVax Therapeutics Receives $1.8 Million in a Phase 2 Small Business Innovation Research Program Award From the National Cancer Institute 2MabVax Therapeutics Receives $1.8 Million in a Phase 2 Small Business Innovation Research Program Award From the National Cancer Institute 3Newly Published Study Shows Dramatic Reduction in Hospital Acquired Infections 2
Contains L-glutamine...
... the 11(R)-LOs of the sea urchin, ... hydra, H. vulgaris. The biological activity ... and tentacle regeneration, respectively, in these ... aspirin-treated recombinant COX-2 is incubated with ...
Rabbit anti-T-box 6...
karyopherin alpha2 (2G7)...
Biology Products: