Navigation Links
CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics
Date:8/25/2008

ardiomyopathy, or HCM, a genetic disease marked by a thickening of heart muscle related to a weakness in individual muscle fibers that causes them to work harder to pump blood and consequently enlarge. HCM occurs in one in 500 people in the United States and is the most common cardiac cause of sudden death in young athletes. About 20 genes associated with HCM have been identified and others are being investigated, she said.

In 2006 Leinwand was named a Howard Hughes Medical Institute Professor, one of 20 faculty nationwide to receive a four-year, $1 million undergraduate education award from the Howard Hughes Medical Institute in Chevy Chase, Md. As part of her successful proposal to enhance science education at CU-Boulder, she initiated an undergraduate laboratory research program known as the Python Project.

In the past two years, CU-Boulder undergraduates working with Leinwand have been studying the genome of the Burmese python, searching out and analyzing particular genes they suspect may be involved in the rapid heart muscle changes.

"Pythons can eat up to 100 percent of their body weight at one sitting, so they have to be able to respond metabolically in a dramatic way," said Leinwand. In addition to the eye-popping changes in heart muscle and metabolism, the python's insulin levels go up 40-fold and their triglycerides rise by more than 100-fold following substantial meals, changes that would "kill a human," she said.

Pythons also exhibit very little muscle loss when at rest, which is of interest to researchers studying diseases like AIDS and cancer and the inevitable process of aging. "We think several of the striking changes we see in python physiology may have significant potential for the pharmaceutical industry," she said.

Hiberna -- which received a $100,000 proof-of-concept investment from CU's Technology Transfer Office to help support the development of the new technology -- has started sequencing the
'/>"/>

Contact: Leslie Leinwand
Leslie.Leinwand@colorado.edu
303-492-7606
University of Colorado at Boulder
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. How the public perceives biotech
2. Monsanto expands sponsorship for Peking-Yale Joint Agrobiotechnology Center
3. Biotech Co. founded by UCLA Scientists to be acquired by Astellas, Pharma Inc.
4. Workshops on biotechnology and water for science journalists
5. Oncolytics Biotech, Inc. announces publication of research
6. Genetic Engineering & Biotechnology News reports on advances in miRNA
7. Biotechnology needs 21st century patent system: Expert
8. Genetic Engineering & Biotechnology News reports on cancer biomarkers
9. Food biotechnology: real world challenges
10. Genetic Engineering & Biotechnology News reports on growing use of cell-based assays
11. Biotechnology key to developing sustainable industries says international panel
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
CU-Boulder, biotech firm team up on python project in search for human cardiac therapeutics
(Date:10/25/2014)... 2014 A recent report, "Genetic Testing Market ... and future genetic testing market. A comprehensive introduction of ... in this report. On account of our analysis of ... strengths and challenges; forecast for genetic testing has been ... grow at a CAGR of around 9% during 2013-2018. ...
(Date:10/22/2014)... Medicine® scientists helps explain how bipolar disorder affects the ... therapies to treat the mental illness. , Scientists ... method recognized with the 2014 Nobel Prize in ... from mice with bipolar-like behaviors. In the synapses (where ... structures with concentrated levels of ANK3 -- the gene ...
(Date:10/22/2014)... 20, 2014  Leading identity analyst firm Acuity Market ... the world,s population will have a chip-based National eID ... . Asia , with its ... for more than 60% of all National eID cards ... -- "The Global National eID Industry Report: ...
Breaking Biology News(10 mins):Genetic Testing Market Outlook 2018 2Bipolar disorder discovery at the nano level 2Half the World's Population Will Have Chip-Based National Electronic Identity (eID) Cards by 2018 2
... Calif., Nov. 19, 2012 Medbox, Inc. (Ticker: MDBX) ... press release they have received many inquiries from shareholders ... during last week,s volatile trading. These inquiries were responded ... to shareholder rapport. In other news, ...
... media only" box at the end of the release ... mouse model of multiple sclerosis (MS), researchers funded by ... to selectively inhibit the part of the immune system ... fibers and facilitates electrical communication between brain cells. ...
... 16 Penguins that face the bitter cold and icy ... warmth during storms. Mathematicians at the University of California, Merced ... aims solely to minimize its own heat loss. Surprisingly, the ... sharing of heat. The results are published in the online ...
Cached Biology News:Medbox Communicates with Shareholders, Comments on Pending Transition to OTC Bulletin Board, and Announces Appearance on Fox Business News Channel 2Research breakthrough selectively represses the immune system 2Research breakthrough selectively represses the immune system 3Research breakthrough selectively represses the immune system 4New model reveals how huddling penguins share heat fairly 2New model reveals how huddling penguins share heat fairly 3
(Date:10/22/2014)... 2014 New test innovations will be the ... (IVD) test industry, especially as companies struggle with reimbursement ... more than 25 testing innovations in important disease areas ... IVD products. Kalorama details the new approaches its biennial survey ... In Vitro Diagnostic Tests , 9th Edition . ...
(Date:10/22/2014)... The North American crystal oscillator market report ... analysis and forecast of revenue. This market was valued ... reach $623.6 million by 2018, at a CAGR of ... TOC of the North American crystal oscillator market report, ... This also provides a glimpse of the segmentation of ...
(Date:10/22/2014)... 2014 Currently offering a comprehensive ... D Weighing, Rice Lake, and Ohaus, Pipette.com has ... The Sartorius CPA Semi-Micro Balance is ideal for ... and user-friendly laboratory balance. , Sartorius is a ... laboratory balances are well known for their high ...
(Date:10/22/2014)... 22, 2014   Synthetic Biologics, Inc. (NYSE ... for serious infections and diseases, announced today that the ... of Allowance for a composition of matter patent application ... program, SYN-004. This is Synthetic Biologics, first allowed ... and adds to the Company,s extensive C. difficile ...
Breaking Biology Technology:Report: Radical New IVD Test Approaches Key To Growth 2Report: Radical New IVD Test Approaches Key To Growth 3The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 2The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 3The North American crystal oscillator market is expected to reach $623.6 million by 2018 - New Report by MicroMarket Monitor 4Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 2Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 2Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 4
... 11 Zimmer Holdings, Inc.,(NYSE: ZMH ; SWX: ... Blair & Company 28th Annual Growth Stock Conference in ... Time., A live webcast of the presentation can ... . The webcast will,be archived for replay following ...
... Rosetta Genomics has Signed a Binding Term Sheet to Acquire Parkway ... ... Significantly Streamline the Development and Commercialization of Rosetta Genomics, microRNA-based ... Needs to Market and Sell its microRNA-based Tests in the U.S. and ...
... DANBURY, Conn., June 11 Biodel Inc. (Nasdaq:,BIOD) today ... as,a new member of its Board of Directors, effective ... of Diabetes Technology,Consultants where he advises Fortune 500 companies ... welcome Barry to our Board of Directors at such ...
Cached Biology Technology:Rosetta Genomics Executes Binding Term Sheet to Acquire U.S. CLIA-Certified Lab to Expedite Commercialization of Diagnostic Tests 2Rosetta Genomics Executes Binding Term Sheet to Acquire U.S. CLIA-Certified Lab to Expedite Commercialization of Diagnostic Tests 3Rosetta Genomics Executes Binding Term Sheet to Acquire U.S. CLIA-Certified Lab to Expedite Commercialization of Diagnostic Tests 4Rosetta Genomics Executes Binding Term Sheet to Acquire U.S. CLIA-Certified Lab to Expedite Commercialization of Diagnostic Tests 5Rosetta Genomics Executes Binding Term Sheet to Acquire U.S. CLIA-Certified Lab to Expedite Commercialization of Diagnostic Tests 6Barry Ginsberg, M.D., Ph.D. Elected to Biodel's Board of Directors 2
BD BioCoat Collagen IV 35 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse collagen type IV....
... application for DNA and protein sequence ... makes complex computational analyses of sequence ... very latest computing technology to set ... are analysed. Features include: Sequence Annotation, ...
... Cytokeratin TYPE II Reacts with most ... epidermal cell keratin of 86 and 58kD ... Broad keratin reactivity is found on human ... Immunogen: Human epidermal cells ...
... The CHEMICON XpressPack™ Colorimetric Detection System ... detection of amplified DNA generated by an ... of a selected target of interest. ... Colorimetric Detection System is a hybridization capture ...
Biology Products: