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CSHL scientists identify a mechanism that helps fruit flies lock-in memories
Date:3/28/2008

he dlg1 gene was dramatically reduced in this brain region. This observation supports the notion that Pumilio helps build memories by selectively altering individual synapses.

The current work is particularly satisfying, Dr. Dubnau noted, because the original hypothesis about Pumilio was extended by computations to make further predictions, which were then brought full circle and tested in vitro, in the lab and in vivo, in living flies. "It's the kind of interdisciplinary collaboration that Cold Spring Harbor is very good at," he observed.


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Contact: Jim Bono
pubaff@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Source:Eurekalert

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