Navigation Links
CSF test can pick up Alzheimer's early
Date:12/20/2011

Analysis of the cerebrospinal fluid can detect whether a person has Alzheimer's disease before symptoms appear. Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have studied biomarkers that offer more reliable diagnosis and, in the longer term, the possibility of effective new treatments.

In Alzheimer's disease, a protein fragment called beta-amyloid forms clumps between the nerve cells of the brain, causing the disease's characteristic effects on memory and function. The nerve fibres also become tangled, causing certain proteins to be released into the cerebrospinal fluid (CSF).

Leading Alzheimers expert

Led by Kaj Blennow, one of the world's leading Alzheimer's experts, researchers at the University of Gothenburg's Sahlgrenska Academy have developed a way of measuring these proteins and protein fragments in the CSF so that they can be used as biomarkers substances that reflect biological processes in the body and allow more reliable diagnoses in people with cognitive disorders.

Detect at early stage

"We found that levels of these proteins change in the CSF even with early symptoms, and we will probably be able to detect changes in the brain at a very early stage of the disease," says doctoral student Niklas Mattsson, whose thesis builds on the results.

International programme

To promote wider use of these new biomarkers, the researchers in Gothenburg have established an international quality control programme for these measurements. Besides facilitating diagnosis, the biomarkers could also be used when new drugs for Alzheimer's are tested. "We hope that a better knowledge about biomarkers will help improve the future care of neurological and psychiatric patients," says Mattsson.


'/>"/>
Contact: Niklas Mattsson
niklas.mattsson@neuro.gu.se
46-031-343-0026
University of Gothenburg
Source:Eurekalert  

Page: 1

Related biology news :

1. Neurimmune Therapeutics Announces Advancement of Alzheimers Program into Preclinical Development
2. Stevens strengthens Dominican Republics Early Warning System for Inundations
3. Reproducing early and often is the key to rapid evolution in plants
4. Early-stage gene transcription creates access to DNA
5. Global Viral Forecasting Initiative receives $11M to implement pandemic early warning system
6. Baby talk: The roots of the early vocabulary in infants learning from speech
7. Gaining too much weight during pregnancy nearly doubles risk of having a heavy baby
8. Hypertension develops early, silently, in African-American men
9. Joslin research finds nearly three-quarters of youths with diabetes insufficient in vitamin D
10. Study: Did early climate impact divert a new glacial age?
11. Water in the early universe
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
CSF test can pick up Alzheimer's early
(Date:7/9/2014)... bladders of healthy women differ from bacteria in ... to researchers from Loyola University Chicago Stritch School ... 9, 2014, in the American Society for Microbiology,s ... communities may play a role in female urinary ... common, yet poorly understood, condition with symptoms similar ...
(Date:7/9/2014)... RIVERSIDE, Calif. Jason Stajich , an associate ... the University of California, Riverside, has been awarded the ... of America, a scientific society dedicated to advancing the ... all kinds including mushrooms, molds, truffles, yeasts, lichens, plant ... peer-nominated and each year recognizes an outstanding early-career mycologist. ...
(Date:7/9/2014)... which animals can be found, concern mounts over the ... range for a host mean new territory for its ... of UC Santa Barbara scientists, including parasitologists Ryan Hechinger ... Journal of Biogeography , Hechinger, Kuris and colleagues ... Hosts may actually lose their parasites when the hosts ...
Breaking Biology News(10 mins):UC Riverside plant pathologist receives national recognition 2Not at home on the range 2Not at home on the range 3Not at home on the range 4
... the University of Verona and the Institute G. Gaslini ... Cytomegalovirus infection in the pathogenesis of atherosclerosis. , Atherosclerosis ... Classic risk factors including smoking, diabetes, hypertension and high ... in the pathogenesis of the disease that also recognises ...
... emergency rooms to treat methamphetamine overdose damages nerve cells ... movement, a new study shows. , The findings, derived ... of the medication, haloperidol, and methamphetamine causes the destructive ... PhD, and his team at Boston University School of ...
... deer are giving new meaning to watching out for other ... and whitetail deer conducted by the University of Alberta in ... showed that both species responded to the recorded distress calls ... fawns, with mule deer mothers responding to both whitetail and ...
Cached Biology News:Cytomegalovirus exacerbates atherosclerosis through an autoimmune mechanism 2Common treatment for methamphetamine overdose may damage brain cells 2Mule deer moms rescue other fawns 2
(Date:1/15/2014)... The Microcompetition with Foreign DNA theory explains how latent ... viruses is the Epstein Barr Virus (EBV), and one of ... a chronic inflammatory disease that destroys the body’s joints. As ... have high concentrations of EBV DNA in their bodies (1). ...
(Date:1/15/2014)... TAIPEI , Jan. 15, 2014 TaiGen Biotechnology ... an exclusive agreement with R-Pharm, a leading Russian pharmaceutical ... in the Russian Federation , ... Commonwealth Independent States (CIS). Nemonoxacin is a novel antibiotic for ...
(Date:1/14/2014)... owners drew up their lists of New Year,s resolutions for 2014, ... my furry companion." Nowadays there are pet salons, dog and cat ... the little canine or feline darlings along wherever mommy or daddy ... toys at the pet store. But anyone who has ever lived ...
(Date:1/14/2014)... In recent years, growing suspicion about the ... development and promotion has led to unprecedented levels of ... concerns about the insidious impact of commercialization of research, ... to the world’s biggest pharmas for illegal marketing activities, ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3
... Cerimon Pharmaceuticals, Inc., announced today the ... topical diclofenac sodium patch Phase III program. The ... clinical studies with Cerimon,s diclofenac patch. The studies ... patch compared to placebo for the treatment of acute ...
... Blood America, Inc. (OTC Bulletin Board: CBAI), the ... http://www.cordblood-america.com ) focused on bringing the life saving ... internationally, today announced an agreement with Shelter Island ... restructuring is a major step forward for Cord ...
... growers are looking for "the sweet spot" - the ideal combination ... of the North Central Soybean Research Program offers suggestions to help ... ... Urbandale, Iowa (PRWEB) February 25, 2009 -- Optimal soybean ...
Cached Biology Technology:Cerimon Pharmaceuticals Initiates Phase III Clinical Studies to Evaluate Its Topical Diclofenac Sodium Patch for Mild-to-Moderate Pain 2Cord Blood America Restructures Debt; Projects to be Cash Flow Positive 2NCSRP Research Director: "Earlier Planting can Increase Soybean Yields" 2NCSRP Research Director: "Earlier Planting can Increase Soybean Yields" 3
PHOTOMAN DIRECT COPY CAMERA, 1 EA. Category: Nucleid Acid Detection Systems....
Recombinant Human Erythropoietin (Tissue Culture Grade)...
One-step, microplate or cuvet, colorimetric, detection range 0.78 ug/dL to 65 ug/dL Zn in serum, plasma, urine, saliva etc. Procedure: 10 min....
Human PDGF R beta MAb (Clone # PR7212)...
Biology Products: