Navigation Links
CRISPR system can promote antibiotic resistance
Date:7/14/2014

r of medicine (infectious diseases) at Emory University School of Medicine and Yerkes National Primate Research Center. "That increased permeability also seems to make them more likely to set off alarms when they are infecting mammalian cells."

Graduate student Timothy Sampson, working with Weiss, found that Cas9 mutant bacteria may be more likely to leak bits of their DNA, a trigger for immune cells to get excited. This is a large reason why Cas9 is necessary for F. novicida to evade the mammalian immune system, a finding published in a 2013 Nature paper.

The regulatory role for Cas9 does not appear to be restricted to F. novicida; Weiss's team found that a Cas9 mutant in Campylobacter jejuni, a bacterium that is a common cause of human gastroenteritis, also has increased permeability and impaired antibiotic resistance.

The findings add to recent discoveries where Cas9 has been found to be involved in virulence the ability to cause disease in a living animal or human -- in various pathogenic bacteria such as Campylobacter and Neisseria meningitides.


'/>"/>

Contact: Quinn Eastman
qeastma@emory.edu
404-727-7829
Emory Health Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. Shortening guide RNA markedly improves specificity of CRISPR-Cas nucleases
2. Disease knowledge may advance faster with CRISPR gene probing tool
3. Electronic Access Control Systems Market is Expected to Reach USD 31.2 Billion Globally in 2019: Transparency Market Research
4. Mouse study: Natural birth may strengthen the immune system
5. Whales as ecosystem engineers
6. A single gene separates aggressive and non-aggressive lymphatic system cancer
7. Biology of infection: A bacterial ballistic system
8. Mountain ecosystems scientists to convene at University of Nevada, Reno
9. Gum disease bacteria selectively disarm immune system, Penn study finds
10. Engineers design systems to help children with special needs
11. EcoHealth 2014 connects researchers addressing impacts of global change on health and ecosystems
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... SHELTON, Conn. , Dec. 22, 2014  NXT-ID, ... or the "Company"), a biometric authentication company focused on ... famous pickpocket, entertainer and security consultant, Apollo Robbins ... Wocket™ biometric smart wallet.  Apollo ... 6th and 7 th , 2015, demonstrating some of ...
(Date:12/19/2014)... --Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has ... North America Perimeter Security Systems Market" report to ... The North American perimeter security market is ... 2014 to 2019. Although the U.S. market holds a ... is expected to grow at a higher CAGR ...
(Date:12/17/2014)... FORT BELVOIR, Va. , Dec. 15, 2014 ... its efforts to make it easier to detect ... supply chain. Today the agency started ... marking. The capability will validate the authenticity of ... supply chain. The new quality control measures will ...
Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3
... researchers have discovered a new mechanism by ... dopamine exert their effects on the brain. ... excess concentrations of dopamine underlie schizophrenia, attention ... The findings therefore provide new research avenues ...
... recent wiki article with more details . New family of ... Guinea pig? Try none of the above. , A team of ... stubby legs and a tail covered in dense hair. But don't ... like a guinea pig or chinchilla. But not quite. In fact ...
... Hill's newest "library" is not the kind that will ... please thousands of plant scientists around the world. Through ... crops that humans around the planet depend on every ... library is a compilation of voluminous genetic data on ...
Cached Biology News:Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs 2Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs 3Scientists discover odd-ball rodent 2Unique library of plant genes germinates, takes root at UNC 2
(Date:12/24/2014)... NEW YORK , Dec. 24, 2014 ... biopharmaceutical company advancing patient care in critical areas, announced ... shares of common stock, and warrants to purchase up ... an offering price of $4.00 per share and $.01 ... price of $5.00, are exercisable immediately, and expire 5 ...
(Date:12/24/2014)... Earlier this year in a June 24 ... the Adult Stem Cell Technology Center, LLC ( ASCTC ... appreciated unique property of adult tissue stem cells. ... in the Past, Important for the Future,” embodied the ... gave the address at the 4th World Congress on ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 Nashville Fertility ... was elected treasurer for the American Society for Reproductive ... knowledge and research in reproductive medicine. In his ... seat on the executive board and will have a ... Dr. Hill has actively supported ASRM since 1984 when ...
(Date:12/24/2014)... 23, 2014 PharmaBoardroom,s new ... today and available for free download , digs deep ... and growth in the sector today. One area ... has been in developing a homegrown pharmaceutical manufacturing base, even ... still remains some way off. A cursory comparison with neighboring ...
Breaking Biology Technology:PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3PharmaBoardroom Releases New Algeria Pharmaceuticals Report 2PharmaBoardroom Releases New Algeria Pharmaceuticals Report 3
... Joseph F. Finn, Jr.,C.P.A. ("Finn"), Assignee ... for,the benefit of creditors, announced today that ... sold at a sealed bid auction on ... hydrophobic thermoplastic,polymers, Spheromers(TM), have superior conventional hydrophilic,bioadhesive ...
... InNexus,Biotechnology Inc., (TSX: IXS.V, OTC Bulletin Board: IXSBF, ... next,generation of monoclonal antibodies based on its Dynamic ... Board of Directors., Mr. Warden was a ... his 23 years of practice, he has represented ...
... Calif., Sept. 9 Energy crop company,Ceres, Inc. ... and high-biomass sorghum hybrids with Range Fuels, Inc. ... the site of Range Fuels,commercial-scale cellulosic ethanol plant, ... southeast of Atlanta., While wood residues will ...
Cached Biology Technology:Spherics, Inc. Announces Sale of Novel Proprietary Bioadhesive Polymers and Oral Drug Delivery System 2InNexus Biotechnology Strengthens Patent Team With New Leadership 2Ceres Trials Energy Crops at Georgia Biofuel Facility 2Ceres Trials Energy Crops at Georgia Biofuel Facility 3
MOUSE ANTI BOVINE TROPONIN I...
Normal donkey serum collected from healthy normal donkeys....
... reagent (F-2902) was developed in collaboration with ... measurement of the kinetics of Fc receptor ... directly in the phagovacuole.2 The Fc OxyBURST ... albumin (BSA) that has been covalently linked ...
Designed for flow cytometric applications intended to identify...
Biology Products: