Navigation Links
CNIO researcher awarded by the Prostate Cancer Foundation
Date:3/13/2014

David Olmos, the Spanish National Cancer Research Centre's (CNIO) Head of the Prostate Cancer and Genitourinary Tumours Clinical Research Unit, has won the 2014 Stewart Rahr-PCF Young Investigator Award, endowed by the Prostate Cancer Foundation (PCF) the leading philanthropic organisation for cutting-edge research into prostate cancer.

Olmos is the first Spanish scientist and one of a select number of European researchers to receive this prestigious award, which is normally awarded to Canadian and US scientists.

The $225,000 prize is earmarked for the Research Unit led by Olmos at the CNIO and that was set up in 2012 with the support of the CRIS Foundation for Cancer Research and the Spanish Association Against Cancer (AECC). The project's objective will be to study the biological mechanisms associated with DNA repair, errors in which could lead to more aggressive forms of prostate cancer.

Olmos states that he feels "privileged as a researcher who, at an early stage of his career, has been able to make a significant contribution to our understanding of prostate cancer," and he highlighted the fact that "previous winners of this award are now world leaders in the field."

Since he joined the CNIO after having worked at the Institute for Cancer Research (ICR) and The Royal Marsden NHS Foundation Trust, London, he and with his team have made important contributions to the field of cancer research; for example, his 2013 description of the first hereditary factor with a prognostic role in prostate cancer.

EARLY DETECTION OF TUMOUR AGGRESSIVENESS

"From these analyses we have identified hereditary alterations in the BRCA1 and BRCA2 genes, which lead to far more aggressive forms of prostate cancer. These or similar alterations could spontaneously occur in other patients and be responsible for aggressive tumour behaviour, even after early diagnosis," warned the CNIO researcher.

"We are currently working with several national and international centres to study samples from hundreds of patients something that will allow us to distinguish between tumours that behave aggressively and those that don't," he added.

Once the genetic markers that allow an estimate to be made of the degree of aggressiveness of prostate cancer have been identified, Olmos will begin working on a generation of new preclinical models that will hasten the development of more effective treatments.

At the same time, his unit at the CNIO is participating in and coordinating several clinical trials in collaboration with other oncology centres in Spain, Europe, the US, Canada and Australia, in order to develop new treatments designed around genetic markers for tumour aggressiveness.

Olmos also added that over the next few years "we will study, together with other renowned international centres, treatments that are especially directed towards the repair of damage and errors in the DNA's genetic code as in the case of PARP protein inhibitors."

LIQUID BIOPSIES FOR THE STUDY OF TUMOURS

Another of the milestones achieved by the CNIO researcher was the 2012 development of a detection technique for aggressive prostate tumours based on simple blood tests. Now, his team is working on the validation of this practice via a large-scale study of up to 300 patients from 30 centres around Spain.

"Our aim is to be able to detect aggressive prostate cancers using a fast, simple blood test," said Olmos.


'/>"/>

Contact: Nuria Noriega
nnoriega@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)
Source:Eurekalert  

Related biology news :

1. New bilateral pilot opportunity will fund collaborations between US and UK bioscience researchers
2. Bucking conventional wisdom, researchers find black sea bass tougher than expected
3. Researchers reveal gap in carbon capture and sequestration education
4. Researchers show that bold baboons learn to solve tasks from other baboons
5. A tale of 2 data sets: New DNA analysis strategy helps researchers cut through the dirt
6. Penn researchers model a key breaking point involved in traumatic brain injury
7. Promising news for solar fuels from Berkeley Lab researchers at JCAP
8. Researchers capture most complete picture of gene expression in cancer cell cycle
9. Scripps Wellderly Genome Resource now available to researchers
10. Researchers find potential target for drug to treat allergic asthma
11. CHOP researcher finds more genetic signals linking weight and heart health risk factors
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
CNIO researcher awarded by the Prostate Cancer Foundation
(Date:3/30/2017)... , March 30, 2017 Trends, opportunities and ... and behavioral), by technology (fingerprint, AFIS, iris recognition, facial ... and others), by end use industry (government and law ... financial and banking, and others), and by region ( ... , Asia Pacific , and the ...
(Date:3/28/2017)... India , March 28, 2017 ... IP, Biometrics), Hardware (Camera, Monitors, Servers, Storage Devices), Software ... Vertical, and Region - Global Forecast to 2022", published ... Billion in 2016 and is projected to reach USD ... between 2017 and 2022. The base year considered for ...
(Date:3/24/2017)... , March 24, 2017 The Controller General ... Controller Mr. Abdulla Algeen have received the prestigious international IAIR ... Continue Reading ... ... picture) and Deputy Controller Abdulla Algeen (small picture on the right) have ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... Diego, CA (PRWEB) , ... May 23, 2017 , ... ... matrix of polymeric molecules, can cause diverse pathologies ranging from food poisoning and catheter ... impact of biofilms is in the tens of billions of dollars per year, there ...
(Date:5/22/2017)... ... May 22, 2017 , ... Stratevi, a boutique firm that partners with healthcare ... has opened an office in downtown Boston at 745 Atlantic Ave. , “We ... to generate evidence on the value they provide, not just to patients, but also ...
(Date:5/21/2017)... ... May 19, 2017 , ... ... educational conference of the American Association of Bioanalysts (AAB) and the College of ... Houston. The conference reinforces AAB’s commitment to excellence in clinical laboratory services and ...
(Date:5/19/2017)... ... May 19, 2017 , ... ... Academic researchers with technologies ripe for commercialization, and who are affiliated with ... are encouraged to submit proposals. QED, now in its tenth round, is the ...
Breaking Biology Technology: