Navigation Links
CHOP partners with Vascular Magnetics, Inc. to pursue commercial potential of blood vessel research
Date:5/9/2011

ter is proud to have played a role in the launch of Vascular Magnetics," said Stephen S. Tang, Ph.D., MBA, president and CEO of the University City Science Center. "VMI's launch is helping to prove our concept that the early addition of business advice is a key element of the tech transfer puzzle."

In a series of animal studies over the past decade, Levy and his team at Children's Hospital have investigated his new approach to stent-based therapy. They have developed nanoparticles, extremely tiny spheres made of a biodegradable polymer impregnated with iron oxide. Under a low-power, uniform magnetic field, much lower than that produced by existing MRI machines, magnetic forces drive the nanoparticles into metal stents and the surrounding artery. The nanoparticles carry a therapeutic payload of the drug paclitaxel, which is released into the surrounding blood vessel tissue in order to slow arterial re-blockage. In 2008, Forbes magazine named Levy's work a promising "disruptive technology," one that might eventually supplant conventional technology, in this case, drug-eluting stents.

As they advance the technique to human trials, Levy and Woodward envision a future therapy called Vascular Magnetic InterventionTM which would serve as an adjunct to artery stenting. A physician would open and stent the blocked artery and then insert a catheter tipped with an expandable magnetic targeting device. The targeting device would be expanded against the walls of the artery.

A magnetic field is then applied to the leg, and paclitaxel-containing magnetic nanoparticles would be administered through the catheter. The targeting device develops strong magnetic gradients that force the nanoparticles into the wall of the artery. After treatment and removal of the catheter, the wall of the artery is uniformly coated with the nanoparticles, which slowly biodegrade and release the drug. The uniform coating provides a higher dose of drug than is achievable with
'/>"/>

Contact: John Ascenzi
Ascenzi@email.chop.edu
267-426-6055
Children's Hospital of Philadelphia
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. D.C.-area science teachers experimenting with partnerships
2. University of Illinois partners in $9.6 million grant to bolster food security in India
3. Researchers develop curious snapshot of powerful retinal pigment and its partners
4. Optiqua-NTU partnership to develop next-generation sensor technology
5. Partnership of genes affects the brains development
6. Tufts announces public launch of the Tufts Institute for Biomedical Partnerships website/HUB
7. memsys-NTU partnership to enhance water desalination technology
8. SU biologist partners with National Park Service to study bison grazing in Yellowstone
9. Partnership Is Game-Changer for the Future of eCommerce
10. Agilent Technologies Expands Agreement to Offer AMDeC Members Preferential Pricing on Products Through AMDeC F.I.R.S.T.™ Vendor Partnership Program
11. National Zoo and partners first to breed critically endangered tree frog
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... State University engineer has developed a patented technique ... explosive devices. The same technique could help police ... M. and Kay L. Theede chair in engineering ... and his research team have created a template-based ... car trunks. The distance detection method called ...
(Date:4/17/2014)... Calif. One day about eight years ago, ... California, Riverside, and her father were on a field trip ... upon an orchid they had never seen before. , Unable ... on orchids. The orchid turned out to be an ... Lophiaris silverarum . , "Lophiaris" is the genus name, ...
(Date:4/17/2014)... is available in German . ... the protection money demanded of him, he can expect his ... however, as fear of the consequences is enough to make ... parasitic birds, which lay their eggs in other birds, nests. ... brood parasites take their revenge by destroying the entire nest. ...
Breaking Biology News(10 mins):Patented research remotely detects nitrogen-rich explosives 2Orchid named after UC Riverside researcher 2Orchid named after UC Riverside researcher 3Fear of the cuckoo mafia 2Fear of the cuckoo mafia 3
... from Murdoch Childrens Research Institute and the University of ... for peanut allergy. It is hoped the test ... approaches and minimise over-diagnosis of peanut allergy in the ... is the standard for diagnosing peanut allergy, and while ...
... a sandstorm over Saudi Arabia, Qatar, Bahrain and southern Iraq and ... first captured on 10 March and the second on 18 March. ... Gulf States in recent days, extending some 1500 km north to ... whipped up dust and sand, causing low visibility and grounding flights ...
... Australian scientist will bring effective screening for tuberculosis (TB) a ... now lives and works. , We still don,t know why ... the Mycobacteria tuberculosis bacterium become sick with tuberculosis ... worldwide every year three every minute. , Centenary Institute ...
Cached Biology News:Test to improve peanut allergy diagnosis 2Young researcher taking fight against global killer to the next level in Vietnam 2
(Date:1/14/2014)... (PRWEB) January 14, 2014 Carahsoft and ... Thursday, January 23, 2014 at 2pm EST (11am PST), ... The topic focuses on how technology can turn raw, ... decisions for government agencies. The online webinar will last ...
(Date:1/14/2014)... BURLINGAME, Calif. , Jan. 14, 2014 As pet owners ... no doubt many of them wrote: "Take better care of my ... and even designer clothes and top-brand carrying cases to take the ... Pet parents might also feel compelled to buy some pricey toys ...
(Date:1/14/2014)... and BETHESDA, Md. , Jan. 14, ... with two institutes from the National Institutes of Health ... bringing safer, more effective treatments to patients on a ... for Advancing Translational Sciences (NCATS) and the National Eye ...
(Date:1/14/2014)... WESTBOROUGH, Mass. , Jan. 14, 2014  RXi ... on discovering, developing and commercializing innovative therapies addressing ... announced that it received the Notice of Allowance ... on its unique self-delivering RNAi compounds (sd-rxRNA®), for ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3
... Computers are getting smaller and smaller. And as hand-held devices ... laptops get more powerful, the race is on to ... information storage on tiny formats. , Researchers at The University ... properties of carbon nanotubes to create a cheap and compact ...
... Nov. 11 In a presentation,today at the ... from Baylor College of Medicine have presented,data from ... measuring the genetic risk factor on chromosome 9p21,detected ... factors to,improve the assessment of individual risk of ...
... part of the,"SCIENCEsuisse" project, swissinfo.ch is presenting profiles ... disciplines. The focus is on,Switzerland,s high international reputation ... SSR idee suisse initiative, in collaboration with,the Swiss ... give readers an insight into what,scientists are studying ...
Cached Biology Technology:Miniaturizing memory: Taking data storage to the molecular level 2Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy 2Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy 3Major Independent Study Underscores Utility of deCODE MI(TM) for Better Predicting Risk of Heart Attack, Informing Statin Therapy 425 Short Films About Top-Level Research on swissinfo.ch 2
... (eIF4E-binding protein II) is involved in translation ... kidney. PHAS proteins bind to eIF-4E, the ... capped mRNA in vitro and in cells. ... of PHAS/eIF-4E complexes. This allows eIF-4E to ...
Goat polyclonal to Lipocalin 2...
... 2 (VMAT2). An antibody made to the ... at ~55 kDa in postnuclear supernatants of ... wild type cells (2). Some additional bands, ... also detected and remain unaffected by the ...
... The INK4a-ARF locus encodes two unrelated ... suppression. p14^ARF^ arrests the cell cycle in ... and promotes the rapid degradation of mdm2 ... stabilization and accumulation. This interaction is ...
Biology Products: