Navigation Links
CHOP expert Dr. Garrett Brodeur honored for career work in neuroblastoma
Date:5/15/2014

The Advances in Neuroblastoma Research Association (ANRA) is conferring its highest honor on pediatric oncologist Garrett M. Brodeur, M.D., of the Cancer Center at The Children's Hospital of Philadelphia (CHOP). Brodeur will receive the ANRA Lifetime Achievement Award tomorrow at the association's international meeting in Cologne, Germany.

The Award singles out a researcher who has achieved worldwide scientific prominence in investigating neuroblastoma over the course of a career. Neuroblastoma is the most common solid tumor of childhood.

A cancer of the peripheral nervous system that typically appears as a tumor in a child's abdomen or chest, neuroblastoma varies greatly in severity, ranging from forms that spontaneously disappear to high-risk subtypes that are difficult to cure. Because of this variability, researchers have sought ways to predict the course of disease in order to select the most appropriate treatment for each patient.

Over his career, Brodeur has focused on identifying the genes, proteins and biological pathways that give rise to neuroblastoma and drive its clinical behavior. He also has built on this knowledge to develop more effective and less toxic treatments for children.

He first demonstrated in the 1980s that some neuroblastoma cells developed multiple copies of the MYCN gene, and this identified a high-risk subtype of neuroblastoma, necessitating more aggressive treatment. This discovery ushered in the current era of genomic analysis of tumors, both in adult and pediatric oncology. Profiling specific molecular alterations in a given patient's tumor helps guide oncologists toward the most appropriate treatment.

Brodeur and colleagues also discovered important neuroblastoma-related genetic changes, such as deletion of the short arm of chromosome 1 and loss of the CHD5 tumor suppressor gene. He collaborated with other CHOP researchers who identified the ALK gene as the gene responsible for
'/>"/>

Contact: Ashley Moore
moorea1@email.chop.edu
267-426-6071
Children's Hospital of Philadelphia
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Worlds leading coral experts to gather in Australia
2. SDSCs big data expertise aiding genomics research
3. Monarch butterflies down again this year as decline continues, says Texas A&M expert
4. Smell and taste experts to discuss new discoveries
5. Agricultural expert outlines path for developing nations to double food production, meet 2050 demand
6. Center for North Sea oil expertise set to boost jobs and growth
7. Coral reef experts to present latest coral reef science during July symposium
8. Divide the Antarctic to protect native species, propose experts
9. World experts meet in Edinburgh to consider how life experiences impact on our genes
10. Mining cleanup benefits from Texas A&M expertise
11. Stanford expert brings climate change science to heated Capitol Hill
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
CHOP expert Dr. Garrett Brodeur honored for career work in neuroblastoma
(Date:5/21/2015)... 21, 2015 The Sync Project™ , ... for health, today announced a collaborative partnership with ... will center on collaboration on original research, joint course ... in the collaboration, The Sync Project and BerkleeICE are ... Medicine" in the 2015-2016 academic year.  ...
(Date:5/19/2015)... 2015  Technology is rapidly advancing, outpacing enterprises, ability ... cloud. Passwords and their management are soon to be ... specifications such as those developed by the FIDO Alliance™. ... presents for BYOD, COPE, IoT, and mobile payments, the ... In response to the call for ...
(Date:5/14/2015)... 14, 2015  Verificient Technologies, Inc., a ... online remote proctoring, announced a new alliance ... and creator of the Canvas Learning Management ... companies will benefit from the seamless integration ... As a fully integrated multifactor biometrics behavioral ...
Breaking Biology News(10 mins):The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 2The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 3HYPR Corp. Biometric Security Integration Kit Shields Applications and Devices Across the Internet of Things 2HYPR Corp. Biometric Security Integration Kit Shields Applications and Devices Across the Internet of Things 3Verificient and Instructure Announce Alliance Partnership to Provide Online Proctoring for K-12 and Higher Education Institutions 2
... of biomedical engineering at Worcester Polytechnic Institute (WPI), has ... National University of Ireland Galway on research and education ... Ireland for the 2009-10 academic year, is the 14th ... a Fulbright Scholar grant. The Fulbright Program, the ...
... NASA embarked on a revolutionary new mission for its ... space as an inter-related whole, rather than as individual ... symposium June 22-24 to examine the accomplishments of 20 ... what discoveries and opportunities lay ahead. Reporters ...
... , Researchers of the University of Granada ... up table based simulator,), which permits to reproduce any part ... cerebellum, the hearing centres or the nervous centres. This scientific ... nervous centres, to do research into new pathologies and diseases ...
Cached Biology News:WPI professor receives Fulbright Scholarship to work on tissue engineering in Ireland 2Development of an artificial simulator of the nervous system to do research into diseases 2
(Date:5/28/2015)... DUBLIN , May 27, 2015 ... addition of Jain PharmaBiotech,s new report "Neuroprotection ... offering. This report describes the role ... and injuries of the nervous system as well ... because many of the underlying mechanisms of damage ...
(Date:5/28/2015)... 28, 2015 Celsion Corporation (the "Company") (NASDAQ: ... commitments from two institutional healthcare investors to purchase an ... stock in an at-the-market registered direct offering and a ... The Company entered into a definitive purchase ... agreed to sell an aggregate of 3,000,000 shares of ...
(Date:5/28/2015)... (PRWEB) May 28, 2015 DryLet, ... use in applications such as animal waste reduction, ... oil reduction in wastewater treatment plants and restaurant ... the World Pork Expo, June 3-5 in Des ... year in a Wall Street Journal article because ...
(Date:5/28/2015)... 2015  PDS Biotechnology Corp. announces preliminary data ... HPV-16, has generated strong T-cell responses in pre-cervical ... is treated by surgical removal of lesions however, ... alternative. Results show that it primes and activates ... and kill precancerous and cancerous cells that display ...
Breaking Biology Technology:Global Neuroprotection Market Report 2015-2024 - Drugs, Markets and Companies 2Global Neuroprotection Market Report 2015-2024 - Drugs, Markets and Companies 3Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $8 Million At-The-Market Registered Direct Offering 3DryLet to Showcase Patented ManureMagicâ„¢ at the 2015 World Pork Expo, June 3-5 in Des Moines, Iowa 2PDS Biotechnology reports positive Phase I clinical trial results in proprietary HPV-Cancer Immunotherapy 2
... Overview , ... the separation and purification of a number of biological molecules. For ... A, or a protein may be purified on the basis of ... purifications take place in a chromatographic column with a relatively large ...
... Purpose , Agricultural ... effectively and efficiently using LC/MS/MS. These agricultural compounds are extracted from ... Overview , ... great importance on the identification and quantitation of insecticides and herbicides ...
... Abstract , ... techniques that produce highpurity total RNA from biological sources such as ... or other manual handling, and produce a highly pure product, free ... These new techniques respond to the ...
Cached Biology Technology:Use of ZipTip Pipette Tips for Microscale Affinity Mass Spectrometry 2Use of ZipTip Pipette Tips for Microscale Affinity Mass Spectrometry 3Identification of Insecticides and Herbicides by LC/MS/MS Using the API 2000 LC/MS/MS System 2Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 2Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 3Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 4Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 5Total RNA Purification from Cultured Cells Using the ABI PRISM 6700 Automated Nucleic Acid Workstation and Total RNA Lysis Reagents 6
Request Info...
Collected from sexually mature, mixed sex, mixed breed cats. Physiochemical constituents are measured to ensure lot-to-lot consistency....
Donor feline serum and plasma...
8 different frozen tissues are mounted on positively charged glass slides...
Biology Products: