Smoking a Single Cigarette May Have Immediate Effect on Young Adults
(#1120190, Wednesday, October 26, 3:00 PM Eastern)
It is well known that smoking leads to a reduction in levels of fractional exhaled nitric oxide (FeNO), which is a marker for airway inflammation. However, there is limited knowledge about smoking-induced changes in the production and exchange of nitric oxide (NO) in young adults. In a study of eight women and eight men with a mean age of 23 years and a smoking history of less than eight pack-years, Greek researchers found that after smoking a single cigarette, the airway tissue concentration of NO increased by 26%, and the FeNO levels decreased by 15.6%. This reduction can lead to a limited flux of NO in the airways of young adults, significantly impairing health. This research demonstrates the negative impact of smoking even one cigarette, especially in young people.
Computer Model Predicts Smoking Cessation Success by Treatment Type
(#1113245, Wednesday, October 26, 5:30 PM Eastern)
Researchers from the Clemson University in South Carolina and the University of North Carolina in Chapel Hill developed a computer-aided model to evaluate the cost-effectiveness of various smoking cessation treatments. Based on their simulation model, patients who received nicotine replacement therapy had an 87% tendency to relapse at 1 year and have a 93% chance at 30 years. Of those who received other therapies, such as bupropion and varenicline, 78% were still smoking at 1 year and 89% remained smokers at 30 years. Of those who quit unassisted, 95% tended to return to prior behaviors at 1 year and 98% at 30 years. The average cost per quality-adjusted life year saved was greater at 30 years for all three treatment groups compared with those who quit unassisted. Smoking cessation treatments increase the probability of patients quitting smoking. The long-term health benefits to patients and the reduced economic
|Contact: Sue Roberts|
American College of Chest Physicians