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CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients
Date:5/16/2008

clinical OM rating of Grade 0 and 79 percent indicated a functional OM rating of Grade 0. Moreover, 23 percent of the 56 patients undergoing radiation therapy alone or in combination with chemotherapy (RT chemo) indicated a clinical OM rating of Grade 0, and 34 percent indicated a functional OM rating of Grade 0. With regard to pain 79 percent of patients undergoing chemotherapy alone and 25 percent of RT chemo-treated patients rated their pain as Grade 0. For dysphagia, eighty-two percent of chemotherapy-treated patients and 30 percent of those undergoing RT chemo treatment reported a dysphagia Grade of 0.

These data confirm that early intervention with Caphosol reduces the occurrence and severity OM, dysphagia and oral pain in patients undergoing chemotherapy, radiation or combination therapy treatments for cancer.

Quality-of-Life Benefits in Patients with Head/Neck Cancer

Oral mucositis occurs in nearly all chemoradiation patients with HNC. Dr. Haas will present a subset analysis of data from 67 HNC patients from the study described above. She will present these data here tomorrow (May 17, 2008) in a poster (#446) entitled, Supersaturated Electrolyte Oral Rinse Aids Quality of Life for Head/Neck Chemoradiation Patients. These data confirm high levels of patient and practitioner satisfaction with CAPHOSOL, suggestive of quality-of-life benefits. The poster reports that more than half (52 percent) of the HNC patients said they were very satisfied with CAPHOSOL in terms of pain relief and oral comfort. None of the HNC patients reported being unsatisfied with CAPHOSOL.

This study showed that among practitioners treating HNC patients, 16 percent of practitioners reported no signs of OM in their patients at the end of the study, and 70 percent assigned an excellent or good rating to CAPHOSOL because none of their patients required additional therapies. Ninety-six percent of the patients indicated they would recomme
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Contact: David Avitabile
davitabile@jfkhealth.com
609-514-5117
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