Navigation Links
CAPHOSOL relieves oral mucositis and improves quality-of-life in cancer patients
Date:5/16/2008

e OM in head and neck cancer patients receiving radiation typically ranges from 34% - 56%, depending upon the specific type of treatment.

Relief of Painful Oral Mucositis

Oncologists at 26 sites enrolled 217 patients into this open-label, non-randomized observational study, called the Caphosol Oral Mucositis Follow-up Observational Registry Trial (COMFORT). Patients must have been undergoing chemotherapy and radiation and at high risk of developing OM. Thirty-one percent of the patients had head and neck cancer (HNC), 31 percent had breast cancer, 13 percent had colon cancer, eight percent had lung cancer, six percent had lymphoma and 11 percent had other tumor types. All patients in this study received CAPHOSOL, administered as an oral rinse, four to 10 times daily for an average of six to eight weeks beginning the first day of treatment. Data were reported for 171 of these patients who had completed folow up at the time the data were analyzed for this interim report.

The study showed that 95 percent of the patients reported favorable OM scores as measured by the percentages of patients indicating Grade 0 (no adverse effects or within normal limits), Grade 1 (mild) or Grade 2 (moderate) symptom severity.

The National Cancer Institute (NCI) clinical rating for OM (oral mucositis assessed during a clinical evaluation) of Grade 0 was evident in 61 percent of patients and Grade 1 clinical OM was seen in 20 percent. An NCI functional rating of OM (reflective of how OM affects diet, swallowing, gastrointestinal function and quality of life) of Grades 0 and 1 were reported in 81 percent of patients. Sixty-five percent of patients ranked their dysphagia symptoms (difficulty swallowing) as Grade 0, while 15 percent rated their symptoms as Grade 1. Grade 0 pain was reported by 61 percent of patients and 20 percent assessed their pain as Grade 1.

Out of 112 patients undergoing chemotherapy alone, 78 percent indicated a
'/>"/>

Contact: David Avitabile
davitabile@jfkhealth.com
609-514-5117
JFK Communcations
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. More than words: childbirth training change improves safety, cuts unnecessary procedures
2. New surgery improves head and neck cancer treatment
3. Herceptin and chemo improves response rates without major adverse effects in HER2 breast cancer
4. Stem-cell transplantation improves muscles in MD animal model, UT Southwestern researchers report
5. New clinical data shows chromium picolinate improves cognitive function
6. Teamwork improves learning and career success
7. Endobronchial valve significantly improves emphysema
8. Exercise improves thinking, reduces diabetes risk in overweight children
9. Genes may play role in risk assessment for prostate cancer among Hispanics and caucasians
10. Tooth loss strongly linked to risk of esophageal, head and neck, and lung cancer
11. Molecular clock could predict risk for developing breast cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)...   EyeLock, Inc. , a market leader of iris-based identity ... to the new role of Senior Vice President of ... of mobile platforms and wearable solutions for EyeLock,s technologies. Gerber ... the semiconductor industry to his role at EyeLock, with expertise ...
(Date:12/24/2014)... , Dec. 23, 2014  Since its launch in December 2014, the ... eliminate the pain of trying to remember their usernames and ... fused to their smartphones. To assist people who have struggled ... company that created 1U and focuses on redefining identity, announced ...
(Date:12/22/2014)... , Dec. 22, 2014 Research and Markets ... of the "The Global Watermarking and Fingerprinting ... http://photos.prnewswire.com/prnh/20130307/600769 This ... media watermarking and fingerprinting markets. Watermarking aims to ...
Breaking Biology News(10 mins):EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3The Global Watermarking and Fingerprinting Markets 2
... While the costs associated with storing nuclear waste and ... legitimate concerns, they may no longer be obstacles on ... by researchers at the University of Notre Dame, led ... geological sciences and concurrent professor of chemistry and biochemistry, ...
... flowing through Venice,s famous canals laps at buildings a little ... rising sea level. Although previous studies had found that Venice ... to slowly sink, and even to tilt slightly to the ... a rate of about 2 millimeters a year," said Yehuda ...
... the BP Deepwater Horizon drilling rig in the Gulf of ... understand the impact that this disaster has had on the ... a rate of approximately 53,000 barrels per day before the ... confirms that oil from the Macondo well made it into ...
Cached Biology News:New paper by Notre Dame researchers describes method for cleaning up nuclear waste 2AGU: Venice hasn't stopped sinking after all 2AGU: Venice hasn't stopped sinking after all 3AGU: Venice hasn't stopped sinking after all 4Study confirms oil from Deepwater Horizon disaster entered food chain in the Gulf of Mexico 2
(Date:1/22/2015)... January 22, 2015 Pipette.com has added ... to their comprehensive portfolio of Eppendorf products. , The ... purchase a Centrifuge 5424/5424 R and receive the following:, ... Eppendorf Research plus or Eppendorf Reference 2 , ...
(Date:1/22/2015)... Diagenode, Inc., a leading global ... and complete solutions for epigenetics research, recently launched ... the need for manual processing. The new ChIPettor ... of histones or transcription factors and a semi-automated ...
(Date:1/22/2015)... 22, 2015  Derma Sciences, Inc. (Nasdaq: ... advanced wound care, announces that AMNIOEXCEL® and AMNIOMATRIX®, ... added to the Premier, Inc. Regenerative Skin Grafting ... the AMNIOEXCEL® and AMNIOMATRIX® product lines, which continue ...
(Date:12/24/2014)...   BioLife Solutions , Inc. (NASDAQ: BLFS ), ... hypothermic storage and cryopreservation freeze media ... tissues  ("BioLife" or the "Company"), today announced that it will ... 2015 (the "Annual Meeting"). Because the expected date ...
Breaking Biology Technology:Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5BioLife Solutions Sets Date for Annual Meeting of Stockholders 2
... provides hope ... for combating problems of resistance -, PALO ALTO, ... today announced that they have entered,into a worldwide strategic ... for viral and bacterial diseases. The,collaboration provides GlaxoSmithKline access ...
... 8 Debiopharm Group,(Debiopharm), a global independent ... conditions, presented Professors Minoru,Toyota and Keiichi Nakayama ... oncology research work. The Awards were presented ... Conference of the JCA in Yokohama,Japan, by ...
... Ill. --- An innovative and inexpensive way of ... in novel forms of advanced materials that pave ... The new fabrication technique, known as soft lithography, ... the ability to scale-up the manufacturing process to ...
Cached Biology Technology:GlaxoSmithKline and Anacor Pharmaceuticals Form Alliance to Develop Systemic Antivirals and Antibiotics Based on Boron Chemistry 2GlaxoSmithKline and Anacor Pharmaceuticals Form Alliance to Develop Systemic Antivirals and Antibiotics Based on Boron Chemistry 3GlaxoSmithKline and Anacor Pharmaceuticals Form Alliance to Develop Systemic Antivirals and Antibiotics Based on Boron Chemistry 4GlaxoSmithKline and Anacor Pharmaceuticals Form Alliance to Develop Systemic Antivirals and Antibiotics Based on Boron Chemistry 5Japanese Cancer Association and Debiopharm Honour Professors Minoru Toyota and Keiichi Nakayama With the 2007 JCA-Mauvernay Award 2Nanofabrication method paves way for new optical devices 2
... endotoxin-free plasmid DNA preparations are prepared ... quantities from 1mg to multi-gram scales. ... customer needs, and glycerol stocks are ... Transformation, clonal selection (Clonal selection includes ...
... 16-independent channels for automated gigaseal patch clamping. ... against voltage-gated ion channels, such as hERG ... The four pipette heads afford more ... channel drug discovery. The glass-coated tunnels ...
... systems need to be able to handle larger ... ports, as well as interface with telemetry systems. ... more, particularly with dogs, pigs, and primates. ... starting time, and the computer can be located ...
... Antibody Plate is a 96-well ELISA-compatible ... This antibody (mouse IgG 1 ) ... glutathione-S-transferase (GST), and binds with ... fusion protein in which the tag ...
Biology Products: