Navigation Links
By adding VSL#3 probiotic to traditional therapies UC patients can improve remission rates
Date:6/7/2012

GAITHERSBURG, MD, June 7 As one of the few probiotics with medical food designation for specific illnesses, VSL#3 has been the subject of a collection of more than 80 studies that have demonstrated its use in the dietary management of IBS, ulcerative colitis, and an ileal pouch. Ulcerative colitis patients, in particular, have been shown to benefit from adding VSL#3 medical food to their prescription drug regimen. One particular study shows that the combination of VSL#3 and traditional drug therapy can improve remission rates over drug therapy alone by 10 to 17 percent, and can initiate remission 47 to 69 percent faster. The 8-week study*, conducted in Rome, involved 90 patients who had newly diagnosed or recently relapsed mild-to-moderate UC and compared the effects of the combination of VSL#3 and balsalazine (Colazal), an anti-inflammatory drug commonly prescribed for the treatment of ulcerative colitis, to the use of balsalazine alone and mesalazine (Canasa) alone.

The trial results concluded that the use of low-dose balsalazide and VSL#3 was significantly superior (p<0.02) in obtaining remission than just the use of balsalazide alone (10 percent improvement) and mesalazine alone (17 percent improvement). The VSL#3/balsalazine combination also initiated remission faster than the drug therapy alone with an average of 4 days versus 7.5 days (balsalazide only) and 13 days (mesalazine only). The improvement of well-being and reduction in bowel frequency was significant as well1.

"Many UC patients try a variety of methods in order to extend their time between flare-ups and obtain remission," said Mary Berry, senior product manager at Sigma-Tau Pharmaceuticals, Inc., maker of VSL#3. "By having a personalized regimen with a drug, such as balsalazide, and adding VSL#3 for their dietary management, patients can see a positive and quick remission that will work for them."

Ulcerative colitis is a chronic disease that causes inflammation and sores, called ulcers, in the inner lining of the large intestine, which includes the colon and the rectum. The inflammation causes erosion of the lining of the colon, leading to bleeding, production of pus, diarrhea, and severe abdominal discomfort.

According to Berry, VSL#3 stands apart from other probiotics since it is not a supplement, but a refrigerated medical food that consists of 8 strains of live, freeze-dried lactic acid bacteria. "It is one of the few probiotic preparations supported by Level 1 (double-blind, placebo-controlled) scientific data, and is the only probiotic recognized as an effective tool in the dietary management of ileal pouch by the American College of Gastroenterology1 and by the Cochrane Review2," says Berry.


'/>"/>

Contact: Nicole Egan
negan@rlapr.com
914-241-0086 x28
Robin Leedy & Associates, Inc.
Source:Eurekalert

Related biology news :

1. Invisible helpers: How probiotic bacteria protect against inflammatory bowel diseases
2. Pain relief with PAP injections may last 100 times longer than a traditional acupuncture treatment
3. Some improved cookstoves may emit more pollution than traditional mud cookstoves
4. The Japanese traditional therapy, honokiol, blocks key protein in inflammatory brain damage
5. Neural stem cell transplants for spinal cord injury maximized by combined, complimentary therapies
6. New discoveries about brain-hand connection sought to improve therapies, treatments, prosthetics
7. Cardio fitness levels of breast cancer patients may affect survival
8. Modest alcohol intake associated with less inflammation in patients with common liver disease
9. Increased fructose consumption may deplete cellular energy in patients with obesity and diabetes
10. New data suggests interferon-free therapy around the corner for HCV patients
11. Drug interactions wont exclude HCV transplant or HIV co-infected patients from treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... PUNE, India , December 1, 2016 /PRNewswire/ ... Market by Authentication type (Fingerprint, Voice), Future Technology (Iris ... Vehicle), and Region - Global Forecast to 2021", ... be USD 442.7 Million in 2016, and is ... 2021, at a CAGR of 14.06%. ...
(Date:11/30/2016)... -- higi SH llc (higi) announced today the launch ... industry thought-leaders and celebrity influencers looking to encourage, ... steps to live healthier, more active lives. ... built the largest self-screening health station network in ... have conducted over 185 million biometric screenings.  The ...
(Date:11/29/2016)... , November 29, 2016 Nearly one billion matches ... Reading ... DERMALOG ... of an efficient Identity Management. (PRNewsFoto/DERMALOG Identification Systems) ... DERMALOG is Germany's largest Multi-Biometric supplier: The company's ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... December 8, 2016 Oxford Gene ... customisable SureSeq™ NGS panel range with the launch of the ... cost-effective study of variants in familial hypercholesterolemia (FH). The panel ... detection on a single small panel and allows customisation by ... includes all exons for LDLR , P ...
(Date:12/8/2016)... ... December 08, 2016 , ... Microbial ... Technology Awards. uBiome is one of just six company finalists in the Health ... addition to uBiome, companies nominated as finalists in this year’s awards include Google, ...
(Date:12/8/2016)...  HedgePath Pharmaceuticals, Inc. (OTCQX: HPPI), a clinical ... to commercialize innovative therapeutics for patients with cancer, ... approved for trading on the OTCQX U.S. market. ... effective today, under the ticker symbol "HPPI." ... must meet high financial standards, follow best practice ...
(Date:12/8/2016)... SAN DIEGO , Dec. 8, 2016 /PRNewswire/ ... ), a leading commercial provider of clinically actionable ... cancer patients, announces that clinical data featuring its ... concordance to tissue biopsy for the detection of ... The results from research sponsored by Sara Cannon ...
Breaking Biology Technology: