Navigation Links
Building healthy bones takes guts
Date:2/14/2013

EAST LANSING, Mich. In what could be an early step toward new treatments for people with osteoporosis, scientists at Michigan State University report that a natural probiotic supplement can help male mice produce healthier bones.

Interestingly, the same can't be said for female mice, the researchers report in the Journal of Cellular Physiology.

"We know that inflammation in the gut can cause bone loss, though it's unclear exactly why," said lead author Laura McCabe, a professor in MSU's departments of Physiology and Radiology. "The neat thing we found is that a probiotic can enhance bone density."

Probiotics are microorganisms that can help balance the immune system. For the study, the researchers fed the mice Lactobacillus reuteri, a probiotic known to reduce inflammation, a sometimes harmful effect of the body's immune response to infection.

"Through food fermentation, we've been eating bacteria that we classify as probiotics for thousands of years," said co-author Robert Britton, associate professor in the Department of Microbiology and Molecular Genetics. "There's evidence that this bacterium as a species has co-evolved with humans. It's indigenous to our intestinal tracts and is something that, if missing, might cause problems."

In the study, the male mice showed a significant increase in bone density after four weeks of treatment. There was no such effect when the researchers repeated the experiment with female mice, an anomaly they're now investigating.

By 2020, half of all Americans over 50 are expected to have low bone density or osteoporosis, according to the National Osteoporosis Foundation. About one in two women and one in four men over 50 will break a bone due to osteoporosis.

Drugs to prevent bone loss in osteoporosis patients are already in wide use, but over the long term they can disrupt the natural remodeling of bone tissue and could potentially have negative side effect
'/>"/>

Contact: Andy McGlashen
andy.mcglashen@cabs.msu.edu
517-355-5158
Michigan State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Building the European Unions Natura 2000 -- the largest ever network of protected areas
2. New study finds a protein combination is best to consume post-workout for building muscle
3. Light weights are just as good for building muscle, getting stronger, researchers find
4. CUNY Energy Institute battery system could reduce buildings electric bills
5. A cells first steps: Building a model to explain how cells grow
6. Stealing lifes building blocks
7. Blood-brain barrier building blocks forged from human stem cells
8. Building global collaboration for biodiversity intelligence
9. Mathematicians find solution to biological building block puzzle
10. Minimally invasive building renovation
11. Natural regeneration building urban forests, altering species composition
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... noise alters how the brain processes speech, potentially ... to neuroscientists at The University of Texas at ... in Ear and Hearing , researchers demonstrated ... affects the brain,s recognition of speech sounds. , ... the population, affecting an estimated 15 percent of ...
(Date:7/31/2014)... The enormous conflagration known as the Rim Fire was ... among mature trees, when it entered the backcountry of ... August 2013. But inside the park, the battle began ... management decisions and drought can combine to fuel large, ... park, it eventually encountered lands where fire had been ...
(Date:7/31/2014)... are inherently different. Each of these cell types has ... metabolism. In the human body, white adipose tissue is ... energy storage. On the other hand, brown adipocytes utilize ... in a few places in the adult human body. ... adipocytes, appear mixed with brown adipocytes in human brown ...
Breaking Biology News(10 mins):UT Dallas study reveals effect of loud noises on brain 2The Rim Fire 1 year later: A natural experiment in fire ecology and management 2The Rim Fire 1 year later: A natural experiment in fire ecology and management 3The Rim Fire 1 year later: A natural experiment in fire ecology and management 4The Rim Fire 1 year later: A natural experiment in fire ecology and management 5Hope for the overweight 2
... tropics and much of the Northern Hemisphere are likely ... the next 20 to 60 years if atmospheric greenhouse ... climate study by Stanford University scientists. The results will ... Change. In the study, the Stanford team concluded ...
... a French doctor, Armand Trousseau, discovered a connection between cancer ... that can lead to venous occlusion. Today it is known ... thus promote the formation of clots. However, clots do not ... but, vice versa, an increased blood clotting tendency may also ...
... who have stopped menstruating have a weakening in the quality ... a bone, despite getting plenty of weight-bearing exercise, a new ... Endocrine Society,s 93rd Annual Meeting in Boston. "Given the ... activities and the fact that up to 24% of young ...
Cached Biology News:Stanford climate scientists forecast permanently hotter summers 2Stanford climate scientists forecast permanently hotter summers 3Blood clotting and bowel cancer risk 2Athletic girls more likely to have impaired bone structure if menstrual cycle stops 2
(Date:8/1/2014)... Waterloo, ON (PRWEB) August 01, 2014 ... researchers has led to a better understanding embryonic ... differentiate and reorganize into structurally and functionally distinct ... devastating physical defects. Prof. Todd McDevitt, Melissa ... that biophysical signals interact with biochemical cues to ...
(Date:7/31/2014)... people over 60 are not donor candidates for bone ... time, making the elderly prone to life-threatening infection and ... now has discovered a reason why. , "We have ... blood-forming cells to maintain blood production over time in ... could be restored for rejuvenation therapies," said Emmanuelle Passegu, ...
(Date:7/31/2014)... , July 31, 2014 The ... today with $25,000 to fund a translational research ... in 2011, the gift was presented at the ... Annual Meeting in Colorado Springs, CO. ... in neurointerventional approaches to neurovascular conditions, SNIS formed ...
(Date:7/31/2014)... ALBANY, New York , July 31, 2014 /PRNewswire/ ... published by Transparency Market Research "Electrodes for Medical Devices ... Fetal Scalp Electrodes, Therapeutic Electrodes - TENS, Pacemakers, Defibrillators, ... Share, Growth, Trends and Forecast, 2013 - 2019," the ... USD 633.6 million in 2012 and is estimated to ...
Breaking Biology Technology:Study Links Biomechanics and Gene Expression in Stem Cells 2Key to aging immune system is discovered 2SNIS Foundation Bestows First Grant Award For Cutting-Edge NeuroInterventional Research 2SNIS Foundation Bestows First Grant Award For Cutting-Edge NeuroInterventional Research 3Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 2Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 3Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 4Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 5Electrodes for Medical Devices Market Expected to Reach USD 1.45 Billion Globally in 2019: Transparency Market Research 6
... a technology entrepreneur can raise the seed capital he needs ... one or more individuals who are legally allowed to make ... do. But fortunately for southeastern Wisconsins tech community, Peter M. ... are wealthy enough to make angel investments to actually take ...
... California, but the failure of flight communications at the Los ... , ,The radio system used by controllers to communicate with ... regular monthly maintenance wasnt performed and shut itself off. The ... them, even as the planes converged well inside FAA minimums ...
... will invest $125,000 to help create a technology transfer ... announced on Monday. , ,The Racine County Economic ... Technology and Innovation will organize the project, which ... Madison-based analog is the Wisconsin Alumni Research Foundation, which ...
Cached Biology Technology:Investor profile: Peter M. Skanavis, tech angel, sees investing as civic duty 2Investor profile: Peter M. Skanavis, tech angel, sees investing as civic duty 3Investor profile: Peter M. Skanavis, tech angel, sees investing as civic duty 4Proactive nightmares 2
... The Yeast Whole Genome ChIP-on-chip Microarray ... of yeast (S. cerevisiae) DNA binding ... with Agilent DNA microarrays. This set ... data with greater true binding events ...
... Salmonella genomes has allowed the development of ... pairs. The S. enterica Typhimurium (strain LT2) ... bp; 4,440 ORFs) and a plasmid, pSLT ... Sigma-Genosys have been designed to amplify all ...
... your lab productivity and allows you to achieve ... Move ahead beyond traditional paper-based weighing processes into ... *Instruments supported: ... XS, XP, PR, SR, PG-S, PG, SG, AT, ...
... ,Components g/500 ml: ,Tryptone ... chloride 2.5 ,Agar 6.0 ,S-Gal ... ,IPTG 0.025 ,Kanamycin 0.0175 ... complete growth medium containing S-Gal ...
Biology Products: