Navigation Links
Building better bones and tissue in the lab
Date:12/15/2008

Tissue engineering holds great promise for the treatment of conditions such as arthritis, osteoporosis, fibrosis, periodontal disease and traumatic injuries. However, bone and cartilage currently produced in the laboratory don't have sufficient strength to function in the body so they're not clinically viable. Dr. Douglas Hamilton, a dental researcher with the Schulich School of Medicine & Dentistry at The University of Western Ontario has received funding from the Canada Foundation for Innovation (CFI) to try to find solutions to that problem.

Hamilton and the Centre for the Study of Biomaterials and Tissue Regeneration has received nearly $163,000 from CFI to purchase specialized equipment to assess cell responses to a variety of mechanical forces and biomaterial types using state-of-the-art molecular biology and imaging techniques.

"In many instances our ability to help tissues such as bone to repair, is limited as we don't fully understand how human tissues respond to the presence of artificial materials. This becomes even more problematic in tissues that are loaded due to normal human activity," says Hamilton. "With the funding from the CFI, we are establishing an innovative laboratory that will allows us to study how cells respond to both mechanical stimulation and biomaterials such as titanium at the same time. We anticipate learning much about how cells sense their environment and subsequently regenerate tissues, which will be important in orthopaedics, dentistry, and cardiovascular medicine."

CFI just announced $45.5 million in new funds to support 251 projects across the country. Western received a total of $1.3 million to fund five research projects. The four other recipients are:

  • Dr. Timothy Regnault, Obstetrics and Gynaecology, Schulich School of Medicine & Dentistry, $288,000, A Laboratory for Investigating the Role of Fetal Programming in Metabolic Syndrome. Regnault is also a scientist with the Lawson Health Research Institute.
  • Dr. Joan Knoll, Department of Pathology, Schulich Medicine & Dentistry, $212,039, Translational Cytogenomic Infrastructure for Detection and Characterization of Chromosomal Abnormalities. Knoll is also an associate scientist at Lawson.
  • Dr. Samuel Siu, Department of Medicine, Schulich Medicine & Dentistry, $359,419, Translational Imaging Centre for Cardiovascular Outcomes Research (TRICORE). Siu is the Chair and Chief of Cardiology.
  • Desmond Moser, PhD, Earth Sciences, Faculty of Science and Geography, Faculty of Social Sciences, $310,051, Nanobeam Materials Analyzer for Probing Planetary Evolution and Resources (NanoMAPPER); an Innovation in Planetary Materials Science


'/>"/>

Contact: Kathy Wallis
kwallis3@uwo.ca
519-661-2111 x81136
University of Western Ontario
Source:Eurekalert

Related biology news :

1. Building blocks of life
2. Rebuilding the evolutionary history of HIV-1 unravels a complex loop
3. Building blocks of life formed on Mars
4. Building disease-beating wheat
5. Building the future -- 21st century nano tools to repair the nervous system
6. International workshop to address capacity building for rainforest leaders
7. In Todays Economy, You Can Strengthen Your Company by Building Your Brand
8. Scientists make chemical cousin of DNA for use as new nanotechnology building block
9. UCI awarded $27.2 million for new stem cell building
10. Building on pyramids of trash
11. Manchester clears first hurdle in €170 million biobank building boom
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2017)... March 2, 2017 Summary This ... understand Merck KGaA and its partnering interests and activities ... Description The Partnering Deals and Alliance since ... activity of one of the world,s leading life sciences ... upon purchase to ensure inclusion of the most up ...
(Date:2/28/2017)... --  Acuant , a leading provider of data capture ... new and core technologies building upon the acquisition of ... desktop Acuant FRM TM facial recognition and match ... manual review of identity documents by accredited professionals. ... most accurate capture software to streamline workflows by securely ...
(Date:2/26/2017)... DALLAS , Feb. 25, 2017  Securus ... justice technology solutions for public safety, investigation, corrections ... of Recidivism and Reentry. "Too often, ... State prisons and county jails are trying to ... of inmates and friends and family members. While significant ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... March 23, 2017 According to a report ... derivatives market is fragmented due to the presence of a large pool ... Thermo Fisher , and Sigma-Aldrich, compete with each other in ... collectively, held more than 76% of this market in 2016.  ... As of now, a ...
(Date:3/22/2017)... Mass. (PRWEB) , ... March 22, 2017 , ... ... scale up human tissue regeneration from small lab samples to full-size tissues, bones, ... how to establish a vascular system that delivers blood deep into the developing ...
(Date:3/22/2017)... , March 22, 2017   iSpecimen ®, ... that Doctors Pathology Service (DPS), a full-service ... the United States , has joined ... Health Information Network (DHIN) to make human biospecimens ... The novel program, announced in 2015 as a ...
(Date:3/22/2017)... March 22, 2017   VWR ... of product and service solutions to laboratory ... has acquired EPL Archives, Inc., an international ... the entire regulated product research, development and ... storage and ancillary services. EPL Archives is ...
Breaking Biology Technology: