Navigation Links
Buck Institute and Biotica to investigate polyketides in extension of healthy lifespan
Date:9/14/2011

The Buck Institute for Research on Aging (Novato, CA) and Biotica Technology Ltd. (Cambridge, UK) today announced a three-year collaboration to investigate polyketides in diseases of aging. Building on observations that rapamycin extends healthy lifespan in various species (Kaeberlein & Kennedy; Nature 2009), the collaborators will evaluate rapamycin analogs and other polyketides in a broad range of age-related disease models to identify novel therapeutics.

"We welcome this collaboration with Biotica with great enthusiasm. Their polyketides represent some of the most novel and promising drug leads for the development of therapeutics for age-related disease," said Buck Institute CEO and President Brian Kennedy, PhD, who added that several Buck laboratories will be involved in the screening process. "We look forward to working with Biotica to move potential therapeutics toward commercialization. We have great respect for the company and their technology - the fact that we will both benefit from commercialization of new discoveries is a harbinger of great things to come."

"Prof. Kennedy and the Buck Institute are recognized as leaders in research on aging, and have played a key role in identifying the life-extending properties of rapamycin," commented Barrie Wilkinson, PhD, Biotica's VP of Research. "We're extremely fortunate to be working with the Buck's outstanding investigators, and to have access to their diverse range of scientific approaches to age-related disease."

The collaboration builds upon an existing relationship between Prof. Kennedy and Biotica, studying longevity-enhancing properties of non-rapamycin polyketides. The recent return of Biotica's rapamycin analog program from Pfizer, in August 2011, has created an opportunity to add value in addition to its current focus on multiple sclerosis (MS) and systemic lupus erythematosus (SLE). In addition to the work on rapamycin analogs, the collaborators expect to identify new polyketides with therapeutic potential in age-related disease.


'/>"/>

Contact: Kris Rebillot
krebillot@buckinstitute.org
415-209-2080
Buck Institute for Age Research
Source:Eurekalert

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. Swiss Institute of Bioinformatics celebrates 10th birthday by presenting major gifts to human health
3. Broad Institute awarded major grant to bolster epigenomics research
4. Salk researcher Terry Sejnowski elected to Institute of Medicine
5. EPA teams with National Geographic Society and World Resources Institute to map ecosystem services
6. M.I.N.D. Institute researchers call for fragile X testing throughout the lifespan
7. House Ear Institute, TGen and Belgian researchers identify gene in age-related hearing loss
8. Rutgers receives US$10 million to establish Institute for Food, Nutrition and Health
9. Stowers Institutes Workman Lab discovers novel histone demethylase protein complex
10. Stowers Institutes Linheng Li Lab expands understanding of bone marrow stem cell niche
11. Stowers Institutes Baumann Lab identifies key step in maturation pathway of telomerase
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/30/2017)... 30, 2017 Trends, opportunities and forecast in ... by technology (fingerprint, AFIS, iris recognition, facial recognition, hand ... by end use industry (government and law enforcement, commercial ... banking, and others), and by region ( North ... Asia Pacific , and the Rest of ...
(Date:3/27/2017)... 2017  Catholic Health Services (CHS) has been ... (HIMSS) Analytics for achieving Stage 6 on the ... In addition, CHS previously earned a place in ... electronic medical record (EMR). "HIMSS Analytics ... EMR usage in an outpatient setting.  This recognition ...
(Date:3/23/2017)... , March 23, 2017 The report "Gesture Recognition and ... Industry, and Geography - Global Forecast to 2022", published by MarketsandMarkets, the market ... CAGR of 29.63% between 2017 and 2022. Continue ... ... ...
Breaking Biology News(10 mins):
(Date:10/9/2017)... 2017  BioTech Holdings announced today identification and ... ProCell stem cell therapy prevents limb loss in ... demonstrated that treatment with ProCell resulted in more ... compared to standard bone marrow stem cell administration.  ... reduction of therapeutic effect.  ...
(Date:10/9/2017)... ... 2017 , ... The Giving Tree Wellness Center announces the ... of consumers who are incorporating medical marijuana into their wellness and health regimens. ... operators of two successful Valley dispensaries, The Giving Tree’s two founders, Lilach Mazor ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... genomic technologies, launched its ProxiMeta™ Hi-C metagenome deconvolution product, featuring the first ... accompanying cloud-based bioinformatics software to perform Hi-C metagenome deconvolution using their own ...
(Date:10/6/2017)... ... October 06, 2017 , ... On Tuesday, October 24th, ABC² ... the first-ever adaptive clinical trial for glioblastoma (GBM). The featured speaker will be ... and open to the public, but registration is required. , WHAT: ABC² ...
Breaking Biology Technology: