With early contributions by electrical engineer William Patterson at Brown, Yin helped to design the custom chips for converting neural signals into digital data. The conversion has to be done within the device, because brain signals are not produced in the ones and zeros of computer data.
The team worked closely with neurosurgeons to implant the device in three pigs and three rhesus macaque monkeys. The research in these six animals has been helping scientists better observe complex neural signals for as long as 16 months so far. In the new paper, the team shows some of the rich neural signals they have been able to record in the lab. Ultimately this could translate to significant advances that can also inform human neuroscience.
Current wired systems constrain the actions of research subjects, Nurmikko said. The value of wireless transmission is that it frees subjects to move however they intend, allowing them to produce a wider variety of more realistic behaviors. If neuroscientists want to observe the brain signals produced during some running or foraging behaviors, for instance, they can't use a cabled sensor to study how neural circuits would form those plans for action and execution or strategize in decision making.
In the experiments in the new paper, the device is connected to one array of 100 cortical electrodes, the microscale individual neural listening posts, but the new device design allows for multiple arrays to be connected, Nurmikko said. That would allow scientists to observe ensembles of neurons in multiple related areas of a brain network.
The new wireles
|Contact: David Orenstein|