Navigation Links
Brown scientists take the petri dish to new dimensions
Date:9/19/2007

PROVIDENCE, R.I. [Brown University] A team of Brown University biomedical engineers has invented a 3-D Petri dish that can grow cells in three dimensions, a method that promises to quickly and cheaply produce more realistic cells for drug development and tissue transplantation.

The technique employs a new dish cleverly crafted from a sugary substance long used in science laboratories that allows cells to self-assemble naturally and form microtissues. A description of how the 3-D dish works appears in the journal Tissue Engineering.

Its a new technology with a lot of promise to improve biomedical research, said Jeffrey Morgan, a Brown professor of medical science and engineering.

Morgan conceived and created the 3-D Petri dish with a team of Brown students led by Anthony Napolitano, a Ph.D. candidate in the biomedical engineering program. Napolitano spent two years perfecting the new dish and recently won a $15,000 award from the National Collegiate Inventors and Innovators Alliance to develop the patent-pending technology into a commercially viable product.

This technology is an inexpensive and easy-to-use alternative to current 3-D cell culture methods, Napolitano said. Its the next generation.

The technology tackles a topic of increasing interest to scientists: creating hothouse cells that look and behave more like cells grown in the human body. Since 1877, scientists have relied on the Petri dish to grow, or culture, cells. The cells stick to the bottom of the dishes and spread out as they multiply. In the body, however, cells dont grow that way. They are surrounded by other cells in three dimensions, forming tissues such as skin, muscle, and bone. This is what happens in Morgans 3-D dish.

The clear, rubbery dish is the size of a silver dollar. It is made from a water-based gel made of agarose, a complex carbohydrate long used in molecular biology. This gel has a few benefits. It is porous,
'/>"/>

Contact: Wendy Lawton
Wendy_Lawton@brown.edu
401-863-1862
Brown University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Brown-Harvard team solves mobile DNAs surgical sleight-of-hand
2. Prions rapidly remodel good protein into bad, Brown study shows
3. How nice, brown rice: Study shows rice bran lowers blood pressure in rats
4. Brown seaweed contains promising fat fighter, weight reducer
5. Brown scientists map structure of DNA-doctoring protein complex
6. Chemicals in brown algae may protect against skin cancer
7. Brown team finds crucial protein role in deadly prion spread
8. Brown cancer biologists identify major player in cell growth
9. Bones in motion: Brown scientists to create new 3-D X-ray system
10. Wisconsin scientists grow critical nerve cells
11. Scientists ID molecular switch in liver that triggers harmful effects of saturated and trans fats
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... of nature as something that we enjoy when we visit ... do we think of ourselves as a part of nature? ... about a house? , The answers to these questions ... actions, our speech and in cultural artifacts. , A new ... the American Indian Center of Chicago and the Menominee tribe ...
(Date:9/30/2014)... professor and Howard Hughes Medical Institute investigator, and ... recipients in the 2014 round of grants from ... BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative ... September 30, provides more than $3 million in ... , The BRAIN Initiative, launched last year, is ...
(Date:9/30/2014)... available in German . ... most expensive foods in the world. Because they grow underground, ... the distinctive smell of truffles is not only of interest ... the direction of the Goethe University Frankfurt have discovered that ... bacteria which are trapped inside truffle fruiting bodies. , White ...
Breaking Biology News(10 mins):The cultural side of science communication 2Salk scientists receive $3 million for BRAIN Initiative grant 2On the trail of the truffle flavor 2
... the European Molecular Biology Laboratory (EMBL) in Heidelberg and ... Barcelona (IRB-PCB) have now added key evidence to claims that ... The study, reported this week in the on-line edition of ... molecules aren't placed in the right locations within stem cells ...
... in India has risen in response to a 20-fold drop ... article in the Nov. 15 issue of Clinical Infectious Diseases, ... country has encouraged people to seek HIV treatment because of ... more than 5 million HIV-infected people living in India have ...
... Hopkins have discovered the presence of functional ion channels ... act like electrical wires and permit ESCs, versatile cells ... types of the body, to conduct and pass along ... of these channels in implanted cells, derived from stem ...
Cached Biology News:A new link between stem cells and tumors 2HIV mortality in India drops with introduction of generic antiretroviral therapy 2Stem cells' electric abilities might help their safe clinical use 2
(Date:9/30/2014)... SoundConnect, an award ... dedicated to supporting business communication solutions, including business ... a carrier services specialist has joined ... connected and productive at all times. This growth ... businesses to cloud communications services. On a ...
(Date:9/30/2014)... Boston, MA (PRWEB) September 30, 2014 On ... Director James Sherley in anticipation of a session that ... -organized “Predictive Toxicology Summit,” scheduled for February 17-18, 2015 in ... September 15, Pharma IQ asked Dr. Sherley to respond to ... stem cell toxicity, challenges to evaluating stem cell toxicity, and ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 Whitehouse ... been chosen by the Parenteral Drug Association (PDA) ... and 19, 2014) on container closure integrity testing. This ... integrity test methods and philosophies detailed in the recently ... Evaluation. The course will span container closure ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 The ... IACRN), a non-profit organization based in Pittsburgh, ... Excellence and Safety (ACRES), a Massachusetts non-profit ... strategic alliance agreement, setting the stage for multiple ... enhance clinical research quality and safety through specialized ...
Breaking Biology Technology:SoundConnect Expands Carrier Services Division 2Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 2Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 3Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology 4Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 2Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 3Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 4IACRN and ACRES to Support Clinical Research Nurses 2IACRN and ACRES to Support Clinical Research Nurses 3
... Biomarker Identification ... and ADME/Tox Applications, LINCOLN, R.I., ... into a worldwide,exclusive license and technology purchase agreement with Corning,Incorporated ... cell lines. Corning paid MultiCell a license fee, and ...
... of Unsaturated Fatty Acids in ... Cardiovascular ... AMRN ) today announced that it has initiated a cardiovascular,development ... acids in cardiovascular disease. Amarin plans to utilize,its extensive know-how ...
... Fourth Fourth Fiscal Fiscal ($ in millions) ... ... $364 $212 $2,807 $1,793 Soybean seed and traits ... Cotton seed and traits 58 52 319 ...
Cached Biology Technology:MultiCell Technologies Signs Worldwide Exclusive License Agreement With Corning Incorporated 2MultiCell Technologies Signs Worldwide Exclusive License Agreement With Corning Incorporated 3Amarin Announces Initiation of Cardiovascular Development Strategy 2Amarin Announces Initiation of Cardiovascular Development Strategy 3Amarin Announces Initiation of Cardiovascular Development Strategy 4Amarin Announces Initiation of Cardiovascular Development Strategy 5Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 2Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 3Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 4Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 5Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 6Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 7Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 8Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 9Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 10Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 11Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 12Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 13Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 14Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 15Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 16Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 17Monsanto Sees Record Sales in Fiscal Year 2007; Seeds and Traits Business Contributes to Strong Fourth Quarter and Year-End Results 18
TRBP1 Antibody...
Complete cell culture media with cytokines...
Complete cell culture media with cytokines...
Consists of 4 separate 100mM solutions (ATP,GTP,CTP and UTP pH 7.5) as sodium salts. 98% Pure by HPLC...
Biology Products: