The Eli and Edythe L. Broad Institute of Harvard and MIT ("the Broad") today announced that it has received a $32.5M grant from the Boston-based Klarman Family Foundation to support a new collaborative effort focused on deciphering how human cells are wired.
This grant will allow the scientific community to expand its understanding of how biological decisions are made in health and disease, paving the way for major treatment breakthroughs.
"Creating a complete catalog of cell circuitry will ultimately have a huge impact on our ability to understand and treat disease," said Broad Institute Director Eric Lander. "The Klarmans are laying the foundation for what I predict will grow eventually into a worldwide effort, with the same spirit and vision of the Human Genome Project. This is a bold step by two extraordinary philanthropists."
The Klarman Family Foundation grant will launch the Klarman Cell Observatory ("the Observatory") at the Broad Institute, which will foster groundbreaking discoveries and technological advances in cell circuit research. It will continue to propel advances in the experimental and computational methods needed to understand cell circuitry, and establish their broad applicability by studying a variety of cell types. Moreover, Observatory researchers will partner with researchers across the Broad and around the world to pursue collaborative projects that shed light on the inner workings of these cells.
Beth Klarman, president of the Klarman Family Foundation, said, "The Cell Observatory has the potential to foster insights into so many different aspects of health and disease, including the biological basis for behavioral health. We feel that providing this funding to the Broad, an institution whose model of collaboration accelerates innovation, is the best way to positively impact the greatest number of people."
Much of what is currently known about cell circuits emerged from decades of rese
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Broad Institute of MIT and Harvard