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Bringing the bling to antibacterials
Date:7/1/2014

e interface between conductors and dielectrics such as between gold and titanium dioxide. The localized electron oscillations at the nanoscale cause the gold nanoparticles to become excited and pass electrons to the titanium dioxide surface, thus allowing the particles to become electron acceptors.

Liu and his team electrochemically anodized titanium to form titanium dioxide nanotube arrays, and then further deposited the arrays with gold nanoparticles in a process called magnetron sputtering. The researchers then allowed Staphylococcus aureus and Escherichia coli to grow separately on the arrays -- both organisms were highly unsuccessful, exhibiting profuse membrane damage and cell leakage.

While silver nanoparticles have been previously explored as an antibacterial agent for in vivo transplants, they cause significant side effects such as cytotoxicity and organ damage, whereas gold is far more chemically stable, and thus more biocompatible.

"The findings may open up new insights for the better designing of noble metal nanoparticles-based antibacterial applications," Liu said.


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Contact: Jason Socrates Bardi
jbardi@aip.org
240-535-4954
American Institute of Physics
Source:Eurekalert  

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