Navigation Links
Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
Date:3/14/2012

Recent breakthroughs in Chikungunya research spearheaded by scientists at A*STAR's Singapore Immunology Network (SIgN) have made great strides in the battle against the infectious disease. Working in close collaborations with Singapore clinician-scientists and international researchers , Dr Lisa Ng, Principal Investigator of the Chikungunya research group at SIgN, led the team to discover a direct biomarker which serves as an early and accurate prognosis of patients who have a higher risk of the more severe form of Chikungunya fever (CHIKF). This means that doctors can now quickly and accurately identify patients at risk, facilitating a more targetted treatment and clinical care at the onset of the disease.

Chikungunya fever, caused by the Chikungunya virus (CHIKV) , is a mosquito-borne, infectious disease endemic to Southeast Asia and Africa. Since its re-emergence in 2005, CHIKV infection has spread to nearly 20 countries to infect millions . Singapore, for instance, was hit twice by Chikungunya fever outbreaks in January and August 2008.

CHIKV infection is characterised by an abrupt onset of fever frequently accompanied by severe muscle and joint pains. Though most patients recover fully within a week, in severe cases, the joint pains may persist for months, or even years. For individuals with a weak immune system, the disease can result in death. With no clinically-approved vaccine or treatment for Chikungunya fever, it remains a worrying public health problem.

To devise strategies to stop CHIKV transmission, Dr Ng's team collaborated with Professor Leo Yee Sin and Dr Angela Chow, clinician-scientists from the Communicable Disease Centre (CDC) at Tan Tock Seng Hospital , to study how the human body responds to CHIKV infection. The team conducted a comprehensive study on the antibody response against CHIKV in patients. They discovered that patients who respond to the disease at the onset with high levels of Immunoglobulin G3
'/>"/>

Contact: Dr. Sarah Chang KC
chang_kai_chen@a-star.edu.sg
65-682-66442
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

Page: 1 2

Related biology news :

1. DOE researchers achieve important genetic breakthroughs to help develop cheaper biofuels
2. Argonne scientists awarded supercomputing time to enable scientific breakthroughs
3. IEEE-USA cites 5 engineering breakthroughs
4. Understanding global climate change through new breakthroughs in polar research
5. Bio-optics breakthroughs: Highlights of medical and bioscience research at Frontiers in Optics 2009
6. Key to future medical breakthroughs is systems biology, say leading European scientists
7. Experimental vaccine protects monkeys against chikungunya
8. Researchers attempt to solve problems of antibiotic resistance and bee deaths in one
9. Scripps Research discoveries lead to newly approved drug for infant respiratory distress syndrome
10. A project to research biological and chemical aspects of microalgae to fuel approach
11. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... Dyslexia, the most commonly diagnosed learning disability in ... that occurs when the regions of the brain ... The use of non-invasive functional neuroimaging tools has ... dyslexia. However, most prior work has focused on ... a gap in our understanding of how multiple ...
(Date:8/28/2014)... Damp and mould in homes could pose a significant health ... published in the Journal of Allergy and Clinical Immunology ... in eight different countries, the research has found that the ... problems in asthma sufferers, as well as increasing the likelihood ... by a team at the University of Exeter Medical School ...
(Date:8/28/2014)... Protected areas conserve biodiversity and more action is needed ... areas, researchers say. , Published in PLOS ONE ... University of Exeter, used meta-analysis - combining results from ... years of research into these areas, to determine whether ... School of Biological Sciences, said protecting an area from ...
Breaking Biology News(10 mins):Dyslexic readers have disrupted network connections in the brain 2Indoor mold poses health risk to asthma sufferers 2Protected areas proven to protect biodiversity 2
... the Biotechnology and Biological Sciences Research Council (BBSRC) have ... genetics, boosting our ability to produce disease- and pest-resistant ... evening (28 July) in the journal Science . ... Beynon at the University of Warwick, has used a ...
... Rochelle, NY, July 29, 2011Intravenous delivery of cold fluids ... and improve neurologic outcomes may not be as effective ... a study reported in Therapeutic Hypothermia and Temperature ... Liebert, Inc. The article is available free online at ...
... grasses, are likely to be pushed aside even more as ... University of California, Berkeley. In the study, which has ... Biology and is now available online, UC Berkeley biologists ... exotic grasses in the state and estimated how climate change ...
Cached Biology News:Plant immunity discovery boosts chances of disease-resistant crops 2Warming climate could give exotic grasses edge over natives 2Warming climate could give exotic grasses edge over natives 3
(Date:8/28/2014)... 2014  Next month, executives from clinical trial marketing firm ... beginning with Patient-Centered Clinical Trials 2014 , to be ... , September 4-5. Patient recruitment experts Bonnie A. ... will share insights on the benefits of employing an ... – from media to mobile apps – can be used ...
(Date:8/28/2014)... 2014  Armetheon, Inc. ( www.armetheon.com ), a ... late-stage cardiovascular drug candidates, today announced that it ... of financing. The Series A round was co-led ... participation from investors that included Atheneos Capital and ... Larry Hsu , the founder of Impax Laboratories. ...
(Date:8/28/2014)... A new market research report detailing ... from Strategic Consulting, Inc., the leading information resource ... Review, Fourth Edition: Global Review of Microbiology Testing ... compares microbiology test volumes, market values and methods ... and forecasts future volumes and market values through ...
(Date:8/28/2014)... Diego, CA (PRWEB) August 28, 2014 ... Pipette.com is offering a promotion for Eppendorf ... Pipette.com customers to purchase the highest quality tubes ... Tubes are ideal for customers doing chemical, medical, ... lab technicians who are not regularly able to ...
Breaking Biology Technology:BBK Worldwide Leads Sessions at Key September Events 2Armetheon Completes $7.0 Million Series A Financing 2Armetheon Completes $7.0 Million Series A Financing 32 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 2Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 3
... , INDIANAPOLIS, Dec. 16 /PRNewswire/ ... Indiana,s life sciences industry and an active venture capital market, ... Retirement Fund, Indiana University, Purdue University, the University of Notre ... the establishment of the INext Fund, a $58 million venture ...
... , , Toronto biotechnology company,s revenues increase ... flow in fiscal 2010 , TORONTO, Dec. 16 /PRNewswire-FirstCall/ ... on virology and biological technologies, today reported financial results ... year ended September 30, 2009, Microbix reported revenues of ...
... , Trial conducted pursuant to Special Protocol Assessment with ... 16 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (NASDAQ: AEZS ... focused on oncology and endocrine therapy, today announced the ... KERX), of a Phase 3 registration clinical trial for ...
Cached Biology Technology:Indiana Industry, University and Community Leaders Capitalize on Next Generation of State's Life Sciences Growth 2Indiana Industry, University and Community Leaders Capitalize on Next Generation of State's Life Sciences Growth 3Indiana Industry, University and Community Leaders Capitalize on Next Generation of State's Life Sciences Growth 4Indiana Industry, University and Community Leaders Capitalize on Next Generation of State's Life Sciences Growth 5Microbix' Pipeline Set To Reach Milestones In 2010 2Microbix' Pipeline Set To Reach Milestones In 2010 3Microbix' Pipeline Set To Reach Milestones In 2010 4Microbix' Pipeline Set To Reach Milestones In 2010 5Microbix' Pipeline Set To Reach Milestones In 2010 6Microbix' Pipeline Set To Reach Milestones In 2010 7Microbix' Pipeline Set To Reach Milestones In 2010 8AEterna Zentaris Partner, Keryx, Initiates Phase 3 Registration Trial with Perifosine (KRX-0401) for the Treatment of Patients with Advanced Multiple Myeloma 2AEterna Zentaris Partner, Keryx, Initiates Phase 3 Registration Trial with Perifosine (KRX-0401) for the Treatment of Patients with Advanced Multiple Myeloma 3AEterna Zentaris Partner, Keryx, Initiates Phase 3 Registration Trial with Perifosine (KRX-0401) for the Treatment of Patients with Advanced Multiple Myeloma 4AEterna Zentaris Partner, Keryx, Initiates Phase 3 Registration Trial with Perifosine (KRX-0401) for the Treatment of Patients with Advanced Multiple Myeloma 5
Immunogen: Synthetic peptide: N(171) H G F L S A D Q QL I K(183) Storage: -20 C, Avoid Freeze/Thaw Cycles...
... polyclonal to Uridine Phosphorylase 1 ( Abpromise ... Antigen: Synthetic peptide: MAATGANAEK AESHNDCPVR ... GTDRYAMYK, corresponding to amino acids 1-99 of ... Entrez Gene ID: 7378 ...
Request Info...
Lingo-1 (K-13)...
Biology Products: