Navigation Links
Breakthrough technology focuses in on disease traits of single cells
Date:7/24/2012

ell parameters; and verify the technology's effectiveness by simultaneously monitoring oxygen, pH, glucose, and ATP responses.

The group will conduct studies involving various kinds of cell perturbation, observing metabolic responses to these interventions and compiling written and graphical procedures to facilitate an understanding of the data. Such stimulus-response experiments could include exposing cells to biochemical agents, an infection, a temporal cue, a drug, or any other type of perturbation.

The Cellarium system can also be applied to a wide range of cell types, including normal, metaplastic, dysplastic, and cancerous cells. While the initial version of the Cellarium will measure oxygen consumption, pH, ATP, and glucose, future work will be aimed at developing new sensors capable of measuring many additional cell parameters.

Providing the proper conditions for the study of individual cells is tricky. The Cellarium relies on environmentally controlled chambers in arrays outfitted with optical sensors capable of being scanned to reveal key parameters over time. To accomplish this, shallow microwellseach with a capacity of about 150 picoliterswill provide protection for the cells under study, which are then sealed in the microwell.

The analytes under consideration can then be studied using extracellular fluorescent sensors capable of multiparameter detection of metabolic processes. The microwells of the Cellarium are each able to hold 1 or more cells, on an array containing thousands of these wells. Once the Cellarium is fully developed by the end of 2012, it should be able to carry out multiparameter dynamic measurements on thousands of cells per run.

Figure 1 outlines the Cellarium process. First, cells are seeded into microwells and incubated under normal culture conditions. (Prior to incubation, various perturbagens may be introduced.) By compressing the aligned sensor array and cell microwell array together,
'/>"/>

Contact: Joseph Caspermeyer
Joseph.Caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Research breakthrough: High brain integration underlies winning performances
2. NTU researchers study little mighty creature for scientific breakthrough
3. Nanotechnology breakthrough could dramatically improve medical tests
4. WanderID Launches Breakthrough ID Product for Children, Seniors
5. Interventional radiology: Potential breakthrough to treat mens enlarged prostate
6. Breakthroughs in Chikungunya research from A*STAR spell new hope for better treatment and protection
7. University of Tennessee Space Institute researchers develop laser technology to fight cancer
8. Geosphere: How geology, technology, modeling, and mapping see into Earths past and present
9. RIH study: Emergency patients prefer technology-based interventions for behavioral issues
10. Engineering technology reveals eating habits of giant dinosaurs
11. Security Technology Executive, SIA and ISC East announce Security Innovation Awards Collaboration
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Breakthrough technology focuses in on disease traits of single cells
(Date:8/31/2015)... August 31, 2015 Growing need ... in government digitization projects to drive India ... published TechSci Research report, " India Biometrics Market Forecast & ... is projected to grow at a CAGR of over ... anticipated on account of extensive use of biometric technology in ...
(Date:8/31/2015)... 2015 Research and Markets ( http://www.researchandmarkets.com/research/st5b3m/saudi_arabia ) ... Biomedical Sensors Market - Growth, Trends & Forecasts (2014-2020)" ... Saudi Arabia Biomedical Sensors market is estimated at $0.23 ... the period 2014-2020 The near future will ... formulation of each individual. These sensors can be set ...
(Date:8/28/2015)... -- According to a new market research ... (Pen & Paper Based, Hosted, Biometrics), Service, Application (Clinical ... Vertical and Region - Global Forecast to 2020", published ... from USD 2.4 Billion in 2015 to USD 7.5 ... (CAGR) of 25.6% from 2015 to 2020. ...
Breaking Biology News(10 mins):India Biometrics Market to Grow at Over 35% Through 2020, Says TechSci Research 2India Biometrics Market to Grow at Over 35% Through 2020, Says TechSci Research 3Saudi Arabia Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts (2014-2020) 2Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 2Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 3Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 4
... tidal energy sufficient to power about half of Scotland could ... north coast of the country, engineers say. Researchers ... tidal power could be generated by turbines placed in the ... gigawatts (GW) could be available. The in-depth assessment by ...
... unusually strong El Ninos, such as the 1983 heatwave ... are likely to double in number as our planet ... the ARC Centre of Excellence for Climate System Science ... CSIRO, published their findings in the journal Nature ...
... in parts of Africa, Asia and South America contributes to ... world,s poor. The parasitic worm lives in the soil and ... blood, the worms cause anemia and, in children, stunted growth ... of Medicine in St. Louis have decoded the genome of ...
Cached Biology News:Island channel could power about half of Scotland, studies show 2Get used to heat waves: Extreme El Nino events to double 2Decoded: DNA of blood-sucking worm that infects world's poor 2
(Date:9/1/2015)... ... September 01, 2015 , ... ... been discovered by researchers at the Keck Graduate Institute and its collaborators. The ... , The findings were published online on August 27 by Scientific Reports, an ...
(Date:8/31/2015)... Milpitas, Calif. (PRWEB) , ... August 31, 2015 ... ... earlier this year to bring together supply chain risk management and resiliency practitioners ... collaborate, develop and share best practices, and be recognized for their innovations and ...
(Date:8/31/2015)... Research and Markets ( http://www.researchandmarkets.com/research/v7fdpx/argentina ) has announced the ... Growth, Trends & Forecasts (2014-2020)" report to their ... is estimated at $0.17 billion by 2018 at a ... The near future will bring Biomedical sensors that are ... sensors can be set to trigger alerts when unpredictable ...
(Date:8/31/2015)... , Aug. 31, 2015  For people with Down ... their day. The biotechnology company, located in the Science ... of the best potential therapies yet for people with Down ... " Correction of Down syndrome and Edwards syndrome aneuploidies ... DNA Research . Elixirgen plans to develop this ...
Breaking Biology Technology:Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 2Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 3Scientists Discover New Use for an Old Therapy Inhibiting Deadly Pathogens Including Ebola and Anthrax 4Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 2Global Supply Chain Resiliency Council Announces Incorporation and Web Site Launch 3Argentina Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts 2014-2020 2New Down syndrome therapy discovered 2
... now has the most,consumer-friendly healthcare system in Europe, ... The EHCI compares all the EU 27 national,healthcare ... point of view, measured by 27 indicators across ... 2006 winner,France in third place. Closely behind the ...
... Abiant, Inc., an Illinois based company,specializing advanced ... disease diagnosis, announces the successful closing of ... an angel,network specializing in early-stage technology, syndicated ... participants. Abiant has developed,partnerships with large pharmaceutical ...
... A novel device, developed by a team led ... traps, detects and manipulates the single spin of ... prevented progress toward spintronics and spin-based quantum computing., ... the research paper brings closer to reality electronic ...
Cached Biology Technology:European Union has 'Three-Speed' Healthcare System - Many Countries Lagging in Reform 2Abiant, Inc. Announces Close on Investment Round 2Quantum device traps, detects and manipulates the spin of single electrons 2
... DNA Visualizer Extraction Kit is manufactured for ... DNA damage byexposure to UV light. The ... is often used for DNA-cloning work. The ... bromide and exposure of UV light damages ...
CleanBox DNA workstation with two 254nm UV lambs & 12-hr timer, 90cm (36-inch)width, single door, 115V (w/crating)...
Mouse monoclonal antibody raised against a full length recombinant PPIL2. NCBI Entrez Gene ID = PPIL2...
Mouse monoclonal antibody raised against a partial recombinant ALAS2. NCBI Entrez Gene ID = ALAS2...
Biology Products: