Navigation Links
Breakthrough reveals blood vessel cells are key to growing unlimited amounts of adult stem cells
Date:3/4/2010

NEW YORK (March 4, 2010) -- In a leap toward making stem cell therapy widely available, researchers at the Ansary Stem Cell Institute at Weill Cornell Medical College have discovered that endothelial cells, the most basic building blocks of the vascular system, produce growth factors that can grow copious amounts of adult stem cells and their progeny over the course of weeks. Until now, adult stem cell cultures would die within four or five days despite best efforts to grow them.

"This is groundbreaking research with potential application for regeneration of organs and inhibition of cancer cell growth," said Dr. Antonio M. Gotto Jr., the Stephen and Suzanne Weiss Dean of Weill Cornell Medical College and Provost for Medical Affairs of Cornell University. "We are indebted to Shahla and Hushang Ansary for founding this Institute and to the Starr Foundation Tri-Institutional Stem Cell Initiative for ongoing support."

This new finding sets forth the innovative concept that blood vessels are not just passive conduits for delivery of oxygen and nutrients, but are also programmed to maintain and proliferate stem cells and their mature forms in adult organs. Using a novel approach to harness the potential of endothelial cells by "co-culturing" them with stem cells, the researchers discovered the means to manufacture an unlimited supply of blood-related stem cells that may eventually ensure that anyone who needs a bone marrow transplant can get one.

The vascular-cell model established in this study could also be used to grow abundant functional stem cells from other organs such as the brain, heart, skin and lungs. An article detailing these findings appears in the March 5 issue of the journal Cell Stem Cell.

In adult organs, there are few naturally occurring stem cells, so using them for organ regeneration is impractical. Until now, strategies to expand cultures of adult stem cells, which invariably used animal-based growth fa
'/>"/>

Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

Page: 1 2 3 4 5 6

Related biology news :

1. Successful genome sequencing of pea aphid is a breakthrough for ecology and agricultural research
2. Understanding global climate change through new breakthroughs in polar research
3. The Full Yield, Inc. Launches Breakthrough Collaboration to Put Food Back at the Heart of Healthcare
4. Research breakthrough could lead to new treatment for malaria
5. Walkerton Tragedy: 10 years of research leads to breakthrough
6. TGen-Scottsdale Healthcare researchers make breakthrough in lung cancer
7. Scientists breakthrough in production of biofuels
8. A global breakthrough in the study of a protein linked to the spread of viruses
9. UC Riverside plant scientists research ranked on top ten breakthrough list for 2009
10. Major breakthrough may pave the way for therapeutic vaccines
11. Breakthrough in monitoring tropical deforestation announced in Copenhagen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... quality of the U.S. diet showed some modest improvement ... a reduction in the consumption of unhealthy trans fats, ... the rich and the poor. , , An unhealthy ... some cancers. Eating a healthy diet is an important ... Evaluating population trends in diet quality is important because ...
(Date:9/1/2014)... how the alteration of a single nucleotidethe basic building block of ... intellectual disability. The study appears in The Journal of ... caused by a defect in a gene on the X chromosome ... in 230 women and 1 in 360 men carry a so-called ... of the FMR1 gene is slightly longer than normal. ...
(Date:8/31/2014)... University of Warwick have discovered that ,good, cholesterol is ... substance, methylglyoxal - MG, was found to damage ,good, ... from the body. , Low levels of HDL, ... with increased levels of MG being common in the ... , Supported by funding from the British Heart Foundation ...
Breaking Biology News(10 mins):Quality of US diet improves, gap widens for quality between rich and poor 2Quality of US diet improves, gap widens for quality between rich and poor 3A nucleotide change could initiate fragile X syndrome 2Sugar substance 'kills' good HDL cholesterol, new research finds 2
... for biodiversity often focuses only on the numbers of ... or in the tropics. But what about the ... world, where the species richness of flowering plants and ... and Chilean taxonomists, ecologists, and philosophers explored the worlds ...
... stories of shepherds and travellers encountering lions, for example ... on flocks and people by these fierce predators. Lions ... but for livestock owners around the Waza National Park, ... loss of human life is rarely reported, lion predation ...
... By applying state-of-the-art holographic microscopy to a major ... have identified the swimming and attack patterns of ... kills in the Chesapeake Bay and other waterways. ... online Early Edition of Proceedings of the National ...
Cached Biology News:The conservation lens 2The conservation lens 3Living with lions 2Researchers view swimming tactics of tiny aquatic predators 2Researchers view swimming tactics of tiny aquatic predators 3
(Date:8/29/2014)... A major challenge before new biotechnology ... realm of Boston-Cambridge, is gaining visibility that can lead ... the Director of Boston’s Adult Stem Cell Technology Center, ... visibility of his company an important priority since he ... to a social media marketing campaign launched ...
(Date:8/28/2014)... SAN DIEGO, California, USA (PRWEB) August 28, 2014 ... at the Department of Physics and Optical Science and ... at the University of North Carolina at Charlotte, and ... has been elected to serve as the 2015 Vice ... photonics. , SPIE 2014 President Philip Stahl announced recent ...
(Date:8/28/2014)... Nevada City, Ca. (PRWEB) August 28, 2014 ... an E3 rating for an alcohol-based hand sanitizer, asks ... fall harvest by comparing the hand sanitizer they’re currently ... Sanitizer Spray . Hand hygiene is critical to fighting ... processing environment. Best Sanitizers believes there are key ...
(Date:8/28/2014)... new research platform uses a laser to ... undergoing stress and heating, an approach likely ... microelectronics and batteries., This new technique, called ... heating and the surface stress of microscale ... discussed the merits of surface-stress influence on ...
Breaking Biology Technology:The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 2The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 3The Adult Stem Cell Technology Center, LLC Participates in Multiple Stem Cell and Regenerative Medicine Conferences Before Year End 4Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 2Food Processors and Food Handlers are Encouraged to Prepare for Fall Harvest by Evaluating Their Current Hand Sanitizer Using Nine Key Criteria 3New analytical technology reveals 'nanomechanical' surface traits 2New analytical technology reveals 'nanomechanical' surface traits 3
... 7 BioEnergy International, LLC,(BioEnergy), a privately-held, ... and biofuels, announces the,addition of Norman R. ... December,2008. Mr. Augustine has a record of ... of industry and government culminating in his ...
... Vaccine Has Potential to Save Millions of Lives, ... Inc.,(IBT), a biotechnology company focused on development of ... have been awarded a multiyear contract for advanced ... Marburg viruses from the National,Institute of Allergy and ...
... Imaging,Diagnostic Systems, Inc., (OTC Bulletin Board: IMDS) a ... today that its distributor,The Oyamo group has place ... (CTLM(R)) for Jerusalem, Israel., (Logo: http://www.newscom.com/cgi-bin/prnh/20040412/IMDSLOGO ... import license from the Israel Ministry of,Health which ...
Cached Biology Technology:BioEnergy International, LLC Announces Norman R. Augustine to Join Advisory Board 2BioEnergy International, LLC Announces Norman R. Augustine to Join Advisory Board 3Integrated BioTherapeutics Awarded NIAID Contract For Up to $65 Million for Development of a Vaccine against Ebola and Marburg Viruses 2Integrated BioTherapeutics Awarded NIAID Contract For Up to $65 Million for Development of a Vaccine against Ebola and Marburg Viruses 3Imaging Diagnostic Systems Receives its First Order for its CT Laser Mammography System for Israel 2
... Avidin is chromatographically purified from egg white. The ... 15.5.The product is in 10 mM phosphate-buffered ... serum albumin, 0.05% sodium azide and 50% glycerol. ... The conjugate is purified by molecular sieving ...
... The Zero Blunt TOPO ... Sequencing is designed for ... of blunt-end PCR products. ... 5-minute TOPO Cloning and ...
Recommend to use at 1000X dilutions for cell culture (e.g. Add 1 ul to 1 ml of culture medium.)...
Recombinant Human CCL21/6Ckine (Mucin Stalk Chimera)...
Biology Products: