Navigation Links
Breakthrough cancer-killing treatment has no side-effects
Date:4/3/2013

Cancer painfully ends more than 500,000 lives in the United States each year, according to the Centers for Disease Control and Prevention. The scientific crusade against cancer recently achieved a victory under the leadership of University of Missouri Curators' Professor M. Frederick Hawthorne. Hawthorne's team has developed a new form of radiation therapy that successfully put cancer into remission in mice. This innovative treatment produced none of the harmful side-effects of conventional chemo and radiation cancer therapies. Clinical trials in humans could begin soon after Hawthorne secures funding.

"Since the 1930s, scientists have sought success with a cancer treatment known as boron neutron capture therapy (BNCT)," said Hawthorne, a recent winner of the National Medal of Science awarded by President Obama in the White House. "Our team at MU's International Institute of Nano and Molecular Medicine finally found the way to make BNCT work by taking advantage of a cancer cell's biology with nanochemistry."

Cancer cells grow faster than normal cells and in the process absorb more materials than normal cells. Hawthorne's team took advantage of that fact by getting cancer cells to take in and store a boron chemical designed by Hawthorne. When those boron-infused cancer cells were exposed to neutrons, a subatomic particle, the boron atom shattered and selectively tore apart the cancer cells, sparing neighboring healthy cells.

The physical properties of boron made Hawthorne's technique possible. A particular form of boron will split when it captures a neutron and release lithium, helium and energy. Like pool balls careening around a billiards table, the helium and lithium atoms penetrate the cancer cell and destroy it from the inside without harming the surrounding tissues.

"A wide variety of cancers can be attacked with our BNCT technique," Hawthorne said. "The technique worked excellently in mice. We are ready to move on to trials in larger animals, then people. However, before we can start treating humans, we will need to build suitable equipment and facilities. When it is built, MU will have the first radiation therapy of this kind in the world."

Hawthorne believes that his discovery was possible only at the University of Missouri because MU has three features that separate it from other universities in the nation, the reason Hawthorne came to MU from the University of California, Los Angeles in 2006.

"First, it is an example of a small number of universities in the United States with a large number of science and engineering disciplines on the same campus," said Hawthorne. "Second, the largest university research nuclear reactor is located at MU. Finally, it has strong, collegial biomedicine departments. This combination is unique."


'/>"/>

Contact: Tim Wall
walltj@missouri.edu
573-882-3346
University of Missouri-Columbia
Source:Eurekalert

Related biology news :

1. Breakthrough could lead to cheaper, more sustainable chemical production
2. Nottingham technology in heart development breakthrough
3. Flu breakthrough: New drug developed to combat flu pandemic
4. Breakthrough study opens door to broader biomedical applications for Raman spectroscopy
5. Explosive breakthrough in research on molecular recognition
6. Stem cell breakthrough could lead to new bone repair therapies on nanoscale surfaces
7. A Spanish breakthrough allows the electroporation of cell cultures for less than 1 Euro
8. Recent breakthroughs in cocoa flavanol research discussed by European research consortium and expert panel
9. Breakthrough: How salt stops plant growth
10. Genetic sequencing breakthrough to aid treatment for congenital hyperinsulinism
11. Plant organ development breakthrough
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/16/2016)... 2016 The global ... reach USD 1.83 billion by 2024, according to ... Technological proliferation and increasing demand in commercial buildings, ... drive the market growth.      (Logo: ... development of advanced multimodal techniques for biometric authentication ...
(Date:6/9/2016)... TURKU, Finland , June 9, 2016 ... French National Police deploy Teleste,s video security solution to ensure ... France during the major tournament ... and data communications systems and services, announced today that its ... Police Prefecture to back up public safety across ...
(Date:6/2/2016)... LONDON , June 2, 2016 ... has awarded the 44 million US Dollar project, ... Security Embossed Vehicle Plates including Personalization, Enrolment, and IT Infrastructure ... world leader in the production and implementation of Identity Management ... in January, however Decatur was selected ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... 2016 More than $4.3 million was raised last ... DHMD ). The gala was held at the American Museum ... and honored Alan Alda and ... and medicine and the public understanding of science. Since the ... event has raised $40 million for the Laboratory,s research and ...
(Date:12/2/2016)... THOUSAND OAKS, Calif. , Dec. 2, 2016 ... AGN ) today announced the submission of a ... for ABP 215, a biosimilar candidate to Avastin ® ... biosimilar application submitted to the EMA. "The ... milestone as Amgen seeks to expand our oncology portfolio," said ...
(Date:12/2/2016)... Research and Markets has announced the addition of ... to their offering. ... , , An ... is anticipated. Nanotechnology will be applied at all stages of ... applications in clinical trials. Many of the assays based on ...
(Date:12/2/2016)... Texas (PRWEB) , ... December ... ... that it will share findings demonstrating the value of DNA microarray comparative ... at this year’s San Antonio Breast Cancer Symposium. Using molecular test results ...
Breaking Biology Technology: