Navigation Links
Brain structure adapts to environmental change
Date:6/13/2011

nment caused an increase of about 70,000 neurons.

"We already knew that enriching environments are neurogenic, but ours is the first report that neural stem cells, currently thought of as 'quiescent,' can accumulate in the live animal," said Dr. Dranovsky. "Since this was revealed simply by changing the animal's living conditions, we think that it is an adaptation to stressful environments. When conditions turn more favorable, the stockpiled stem cells have the opportunity to produce more neuronsa form of 'neurons on demand.'"

The researchers also looked at neuronal survival. They found that social isolation did not cause it to decrease. Scientists already knew that environmental enrichment increased neuronal survival―further increasing the neuron population.

To a lesser extent, location within the hippocampus affected whether stem cells became neurons. While the ratio of stem cells to neurons remained constant in the lower blade of the dentrate gyrus, it varied in the upper blade.

Age also affected the results. After three months, the brains of the isolated mice stopped accumulating neural stem cells. But the mice in enriched environments continued to produce more neurons.

Dranovsky and his team now want to see whether this hippocampal response is specific to social isolation or is a more general response to stress. Another question is whether all neural stem cells have the same potential to produce neurons.

"The long-term goal." Said Dr. Dranovsky, "is to figure out how to instruct neural stem cells to produce neurons or more stem cells. This could lead to the eventual use of stem cells in neuronal replacement therapy for neurodegenerative diseases and other central nervous system conditions."


'/>"/>

Contact: Ann Rae Jonas
arj2116@columbia.edu
212-305-6535
Columbia University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Birdsong independent of brain size
2. Emerging research in brain connectivity reveals new understanding of neurological disorders
3. New neurons take 6 months or more to mature in non-human primate brain
4. Deciding to stay or go is a deep-seated brain function
5. Early light refines the brains circuitry for vision
6. Changes in brain circuitry play role in moral sensitivity as people grow up
7. Pitt team recreates brain cell networks with new view of activity behind memory formation
8. What doesnt kill the brain makes it stronger
9. High iron, copper levels block brain-cell DNA repair
10. Building brains: An introduction to neural development
11. Surprising findings from studies of spontaneous brain activity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 9, 2015 Valid S.A. ("Company") (BM&FBOVESPA: VLID3 ON), is ... the State of Washington,s Department of ... enrollment and central issuance system for driver,s licenses and identification ... project planning and development will start in January 2015, with ...
(Date:1/22/2015)... Hall E -   EyeLock Inc. , a market leader ... its EyeLock ID technology integrated in a 3D printed automobile ... Ridge National Laboratory (ORNL) at the 2015 North ... is being used to validate the driver and authorize the ...
(Date:1/22/2015)... NXTD and NXTDW) a biometric authentication company focused on ... Wocket™ smart wallet at CES 2015 in Las Vegas ... the "11 Hot Products at CES" in a review published in Wired.com, ... Newseveryday.com and "The top 10 gadgets from CES 2015" by Danny ...
Breaking Biology News(10 mins):Valid USA Signs Contract For Washington Driver's License Issuance 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3
... from the National Human Genome Research Institute (NHGRI), part ... that mammalian chromosomes have evolved by breaking at specific ... many of the breakage hotspots are also involved in ... July 22 issue of the journal Science, a team ...
... elephants and rhino from extinction could be made more ... as their habitats. , Scientists at the Zoological Society ... London have identified fundamental new approaches to improve the ... journal Science, the largest study of its kind analyses ...
... migration time on Cape Cod again, the time of year ... It's a sign of spring to the fishermen who make ... at the Marine Biological Laboratory (MBL), it triggers an influx ... who return here faithfully every summer to study the squid ...
Cached Biology News:Multi-species genome comparison sheds new light on evolutionary processes, cancer mutations 2Multi-species genome comparison sheds new light on evolutionary processes, cancer mutations 3Size matters: Preventing large mammal extinction 2Gifts from the sea 2Gifts from the sea 3
(Date:1/23/2015)... 23, 2015 Portal Solutions , a ... on Microsoft Office 365 and SharePoint platforms , today ... program for being one of the region’s fastest-growing mid-sized companies ... growth. , “To be recognized a second year in ...
(Date:1/22/2015)... Jan. 22, 2015  Transwestern | RBJ today announces the firm ... space for Shire a leading biopharmaceutical company, at Two Ledgemont ... RBJ,s Robert Richards , president, and Brian Cohen ... the entire five-floor building at 95 Hayden Ave. ...
(Date:1/22/2015)... 21, 2015 Cambridge Semantics, the leading provider ... announced that 2014 was a record-breaking year across the board ... the Anzo Smart Data Platform and our Smart Data solutions, ... from diverse data which led to record growth for the ...
(Date:1/22/2015)... Boulder, CO / Rootstown, OH (PRWEB) January 22, 2015 ... sensitive detection platform, announced today that it has received AOAC-PTM ... O26, O45, O1O3, O111, O121, and O145; collectively referred to ... (E. coli) O157, at 1 colony forming unit (cfu) per ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Cambridge Semantics Announces Record Results for 2014 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2
... April 12, 2011 EMC Corporation (NYSE: ... today announced that EMC Isilon® customers City ... and the Translational Genomics Research Institute (TGen) are ... the Era of Big Data," at Bio-IT World Conference ...
... Careers, the leading online career service for life science ... Memberships. Previously, Bio Careers was available only to life ... Now, membership is open to individuals associated with top-ranked ... the Academic Ranking of World Universities.   ...
... Sanford Rose Associates - Charleston, a leading ... technology, has promoted Bonnie R. Siegel as Partner ... Health information technology continues to be the ... healthcare marketplace. Bonnie will continue to focus on ...
Cached Biology Technology:EMC Isilon Customers Discuss the Big Data Opportunity in Life Sciences at Bio-IT World Conference 2011 2Online Career Service for Postgraduate Life Scientists Expands Membership to Individuals 2Sanford Rose Associates - Charleston Promotes Bonnie Siegel to Partner 2
... Molecular Imaging Systems offer an optional ... science researchers to conveniently capture and ... organs and whole animals with molecular ... of molecular signals that are generated ...
...
... Features hardwall acrylic panels mounted ... to form a free-standing modular ... Class 10/ISO 3. Optional ceiling ... ionizers are configured to customer ...
... The first high-density serum biomarker chip ... serum proteins. An antibody chip containing 120 ... tool that enables biomarker discovery scientists to ... detection, benefits of therapy and the likelihood ...
Biology Products: