Navigation Links
Brain scans detect autism's signature

An autism study by Yale School of Medicine researchers using functional magnetic resonance imaging (fMRI) has identified a pattern of brain activity that may characterize the genetic vulnerability to developing autism spectrum disorder (ASD). Published today in the early edition of Proceedings of the National Academy of Sciences, the study could eventually lead to earlier and more accurate autism diagnosis.

ASD is defined by impaired social interaction and communication, and can disrupt the brain's ability to interpret the movements of other people, known as "biological motion." ASD is a strongly genetic, highly prevalent disorder.

Using fMRI, Yale researchers Martha Kaiser, Kevin Pelphrey and colleagues scanned the brains of children with autism and their unaffected siblings, as well as those of typically developing children as the three groups watched animations of biological movement. The study included 62 children age 4 to 17.

The team identified three distinct "neural signatures": trait markersbrain regions with reduced activity in children with ASD and their unaffected siblings; state markersbrain areas with reduced activity found only in children with autism; and compensatory activityenhanced activity seen only in unaffected siblings. The enhanced brain activity may reflect a developmental process by which these children overcome a genetic predisposition to develop ASD.

"This study may contribute to a better understanding of the brain basis of ASD, and the genetic and molecular origin of the disorder," said first author Kaiser, a postdoctoral associate in the Yale Child Study Center.


Contact: Karen N. Peart
Yale University

Page: 1

Related biology news :

1. Brain size and a trip to Disneyland
2. Where did you get those eyes and that brain?
3. Technology developed at Queens University allows medical workers to better assess brain injuries
4. Bat brains offer clues as to how we focus on some sounds and not others
5. Caltech scientists describe the delicate balance in the brain that controls fear
6. Trojan Horse ploy to sneak protective drug into brains of stroke patients
7. The brains of Neanderthals and modern humans developed differently
8. Scientists discover how the songbirds brain controls timing during singing
9. PET scans reveal estrogen-producing hotspots in human brain
10. Study provides treatment hope for long term effects of brain trauma
11. New Brain Connectivity journal captures latest advances in neuroscience research
Post Your Comments:
(Date:5/12/2016)... May 12, 2016 , a ... the overview results from the Q1 wave of its ... wave was consumers, receptivity to a program where they ... a health insurance company. "We were surprised ... says Michael LaColla , CEO of Troubadour Research, ...
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 /PRNewswire/ ... product subsidiary of Infosys (NYSE: INFY ), and ... global partnership that will provide end customers with ... banking and payment services.      (Logo: ... area for financial services, but it also plays a fundamental ...
(Date:4/26/2016)... -- Research and Markets has announced the ...  report to their offering.  , ,     (Logo: ... forecast the global multimodal biometrics market to grow ... 2016-2020.  Multimodal biometrics is being implemented ... healthcare, BFSI, transportation, automotive, and government for controlling ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... Md. , June 23, 2016 A person ... from the crime scene to track the criminal down. ... the U.S. Food and Drug Administration (FDA) uses DNA evidence ... Sound far-fetched? It,s not. The FDA ... sequencing to support investigations of foodborne illnesses. Put as simply ...
(Date:6/23/2016)... , June, 23, 2016  The Biodesign Challenge (BDC), ... new ways to harness living systems and biotechnology, announced ... (MoMA) in New York City . ... participating students, showcased projects at MoMA,s Celeste Bartos Theater ... Antonelli , MoMA,s senior curator of architecture and design, ...
(Date:6/23/2016)... ... ... In a new case report published today in STEM CELLS Translational Medicine, doctors ... being treated for breast cancer benefitted from an injection of stem cells derived from ... frequent side effect of cancer treatment. , Lymphedema refers to the swelling ...
(Date:6/23/2016)... , June 23, 2016 On Wednesday, ... at 4,833.32, down 0.22%; the Dow Jones Industrial Average edged ... closed at 2,085.45, down 0.17%. has initiated coverage on ... ), Nektar Therapeutics (NASDAQ: NKTR ), Aralez Pharmaceuticals ... (NASDAQ: BIND ). Learn more about these stocks ...
Breaking Biology Technology: