Navigation Links
Brain enzyme may play key role in controlling appetite and weight gain
Date:12/12/2008

peptides [small chains of amino acids] that normally stimulate feeding," says Dr. Schwartz. "When we lowered S6K activity, we saw essentially the opposite response."

The way increased S6K activity reduced the rats' food intake is important, says Dr. Schwartz: reducing the average size of meals rather than changing the number of meals over the course of a day. So the animals apparently were sated faster and therefore ate less at every meal.

In another experiment, the researchers tested whether increased S6K activity would protect against the natural tendency of mammals on a high-fat diet to overeat. People deal with all those calories by putting on extra weight and becoming insensitive to insulin two of the hallmarks of metabolic syndrome, a group of risk factors that raise the risk of heart disease and type 2 diabetes.

When animals on a high-fat diet were given the S6K-enhancing virus, they overate less and gained weight more slowly than control animals, the researchers report. In addition, the virus-enhanced animals had lower body-fat levels and better glucose tolerance than the control group.

Overall, the study shows that S6K acts as a kind of food-sensing thermostat in mammals, increasing or decreasing feeding behavior and metabolism to maintain a normal energy balance. "These findings show that it may be possible to control obesity and other human metabolic disorders by developing drugs that regulate S6K activity," says Dr. Schwartz.


'/>"/>

Contact: Michael Heller
mheller@aecom.yu.edu
718-430-4186
Albert Einstein College of Medicine
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Maintaining the brains wiring in aging and disease
2. UNC expands brain imaging study of infants at risk for autism
3. Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age
4. New molecular insight into vertebrate brain development
5. Forgotten but not gone -- how the brain takes care of things
6. Yale researchers unravel mystery of brain aneurysms
7. Interaction between gene variants may alter brain function in schizophrenia
8. Social interactions can alter gene expression in the brain, and vice versa
9. Pitt research identifies new target in brain for treating schizophrenia
10. Brain recognizes verbal oh dear wave
11. Ultrasound shown to exert remote control of brain circuits
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Brain enzyme may play key role in controlling appetite and weight gain
(Date:7/11/2014)... increased risk of kidney injury related to the use ... mass of HES molecules, according to a report in ... International Anesthesia Research Society (IARS). , The "total mass ... on cultured human renal proximal tubule cells (PTCs), concludes ... of University Hospital Wrzburg, Austria. Other factorssuch as ...
(Date:7/11/2014)... type 1 can inhibit voltage-gated calcium channel, ... release. However, some scholars demonstrated that cannabinoid ... influx and increase neurotransmitter release. Dr. Yi ... to Tongji Medical College, Huazhong University of ... voltage-clamp and calcium imaging in cultured trigeminal ...
(Date:7/10/2014)... Fe, Albuquerque, and other major cities in New Mexico, ... treated municipal wastewater rather than precious potable water supplies. ... 40% of all golf courses receive treated effluent. Reusing ... , Additionally, golf courses and homeowners alike fertilize their ... fertilizer is nitrate. A New Mexico State University turfgrass ...
Breaking Biology News(10 mins):In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2'Tailored' water -- the latest in lawn care 2
... ,Communication Intelligence Corporation (OTC Bulletin Board: CICI) ("CIC"),a ... process,automation in the financial industry and the recognized ... of Michael Betts to,the CIC Board of Directors. ... experience in the insurance and,financial services industries and ...
... McConnell, Director of,National Intelligence and James R. Clapper, ... valuable insights into the intelligence,challenges of the future, ... Community 100 Day Plan for INTEGRATION and COLLABORATION. ... the Director of National Intelligence and the National,Defense ...
... IdentiPHI announces the launch of SAFmodule(TM) 3.1 ... Services (NMAS) biometric authentication methods, AUSTIN, ... brings,secure, easily managed biometric authentication to Novell(R) ... with Novell,s,Novell Modular Authentication Service (NMAS(TM)) security ...
Cached Biology News:Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors 2Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors 3IdentiPHI Re Launches SAFmodule Software to Secure Novell(R) Networks 2
(Date:7/10/2014)... (PRWEB) July 10, 2014 Product ... in very low abundance and are often “lost ... and time-consuming. , Join presenters Dr. Rowel Tobias, ... Dr. John Anders, Head of Quality at Nanotherapeutics, ... approach that can speed detection and quantitation while ...
(Date:7/10/2014)... 2014 Unraveling life’s mysteries can intrigue, ... Archer Family purchased a DNA test to ... up with a lifetime of memories, sharing, and closeness. ... members’ DNA genuinely brought the family closer together. ... into genetic history and prior to taking the ...
(Date:7/10/2014)... 10, 2014 Senior supply chain management ... associations, addressed the challenges of “Reducing Cost, Lead Time, ... through strategic sourcing. Describing the partnership of the Bio ... Chain Management Institute ( SCMI) of the University ... 24 at the Kroc Institute of Peace and Justice ...
(Date:7/10/2014)... , July 10, 2014 /PRNewswire-iReach/ -- Tute ... interpretation, today announced an agreement with Lineagen, ... for Lineagen,s NextStep Dx PLUS.  Lineagen, ... and neurological disorders, currently offers FirstStep Dx ... testing service used by healthcare providers as ...
Breaking Biology Technology:Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 2Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 3Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 4Ancestry DNA Test Reveals a Controversial and Undiscovered Family History 5Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4
... Pa., June 22 Environmental Tectonics Corporation,s (OTC Bulletin ... announced that the Japan Ministry of Health, Labor and ... foreign manufacturer in Japan. , , ETC worked ... to help ensure that our monoplace hyperbaric chambers passed ...
... , BERLIN, NIMES, France and RICHMOND, Calif., June ... company, Cezanne, and Lumiphore Inc., a biotechnology leader ... in high-value applications, announced that they have signed ... in BRAHMS diagnostic tests. , , ...
... NEW YORK, June 22 NeoStem, Inc. (NYSE Amex: ... storage of adult stem cells for future medical need, was featured ... Street," on June 18, 2009. Also, on June 16, 2009, ... in a substantial Fortune Magazine article distributed by CNNMoney.com. ...
Cached Biology Technology:Environmental Tectonics Corporation's BioMedical Division Achieves Foreign Manufacturer Accreditation in Japan 2Environmental Tectonics Corporation's BioMedical Division Achieves Foreign Manufacturer Accreditation in Japan 3Environmental Tectonics Corporation's BioMedical Division Achieves Foreign Manufacturer Accreditation in Japan 4BRAHMS, Cezanne and Lumiphore Announce Partnership for Diagnostic Tests 2BRAHMS, Cezanne and Lumiphore Announce Partnership for Diagnostic Tests 3NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article 2NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article 3NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article 4NeoStem Featured in Business Week; 'Promising' Adult Stem Cell Market Discussed in Fortune-CNNMoney.com Article 5
Medium for cryopreserving subcutaneous or omental preadipocytes...
... Exclusive ultra high yield technology is fast ... Amplifies aRNA for gene array analysis ... , Kits specific for templates ... promoters , All kits contain ...
Rad 51C Immunogen: His-tagged human Rad 51C, over-expressed in E. coli Storage: 4 C...
...
Biology Products: