Navigation Links
Brain connections for stress -- lessons from the worm
Date:4/18/2010

Did you ever wonder how you are able to perform complex tasks - even under stress? And how do emotions and memories mould your ability to live your everyday lives? The answer is just beginning to be understood and lies in hidden circuits in the brain.

Pioneering work by Roger Pocock, a newly arrived Group Leader at the research centre BRIC, University of Copenhagen, reveals the remarkable ability of organisms to activate latent neuronal circuits under stressful conditions. It is suggested that such circuits form part of an escape response that enables animals to sense their environment and adapt their behaviour under unfavourable conditions. This work is being published in the journal Nature Neuroscience on April 18 th*.

The human brain contains billions of neurons that build trillions of connections making it very complex to study behaviour at the level of the single neuron. Therefore, the Pocock laboratory uses the simple nervous system of the microscopic worm, Caenorhabditis elegans, to model how our environment modifies gene function, neuronal circuitry and behaviour. Using C. elegans, which contains just 302 neurons, Dr Pocock has identified a hidden neuronal circuit that modulates sensory perception under stress. Specifically, this work discovered that physiological detection of hypoxic (low oxygen) stress results in the activation of a hidden neuronal circuit involving the neuromodulators serotonin and the neuropeptide Y receptor.

This work implicates that mechanisms coupling hypoxia, serotonin and neuropeptide signaling also modifies behaviour in mammals. In fact, hypoxic stress enhances serotonin and neuropeptide production in specific regions of the mammalian brain, however, the functional output of this is poorly understood.

Roger Pocock did the experiments for this article at Columbia University, New York, where he worked as a researcher before coming to Denmark. He has previously
'/>"/>

Contact: Katrine Sonne-Hansen
katrine.sonne@bric.ku.dk
453-532-5648
University of Copenhagen
Source:Eurekalert  

Page: 1 2

Related biology news :

1. A brain-recording device that melts into place
2. Investigational immune intervention slows brain shrinkage in Alzheimers patients
3. Dual approach gives a more accurate picture of the autistic brain
4. UCLA researchers make first direct recording of mirror neurons in human brain
5. Searching for brains defenses to ward off infections, prevent memory loss
6. Depression associated with sustained brain signals
7. This is your brain on Cryptococcus: Pathogenic fungus loves your brain sugar
8. Brain tumors: Tissue stem cell turning into tumor stem cell
9. Impaired brain connections traced to schizophrenia mutation
10. New brain nerve cells key to stress resilience, UT Southwestern researchers find
11. Insulin-like signal needed to keep stem cells alive in adult brain
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Brain connections for stress -- lessons from the worm
(Date:9/11/2014)... are more than 300,000 cases of Lyme disease in the ... to the CDC were concentrated heavily in the Northeast and ... In fact, the disease gets its name from the northeastern ... However, a new article published in the Journal of ... disease Ixodes scapularis , also known as blacklegged ...
(Date:9/11/2014)... known for her work as a high-energy experimental particle ... international consortium of scientists who detected the Higgs boson ... Hadron Collider. , But Bean, a professor of physics ... a long-running passion for engaging the public with science. ... artists and museum educators in the creation of "Quarked," ...
(Date:9/11/2014)... A new study led by the Wildlife Conservation ... where leopards prowl at night, it,s not livestock that,s ... friend. , The study, which looked at scat samples ... that 87 percent of their diet was made up ... most common prey item at 39 percent and domestic ...
Breaking Biology News(10 mins):Physics researcher to advise faith-based office in US Department of State 2Study: Cat bites dog 2
... men die of prostate cancer. It,s Australia,s second worst ... cancer on women. Current therapies for prostate ... the tumour or cutting off the supply of the ... impotence. Growing cells need an essential nutrient, the ...
... of the scientific and technical publishing business of John Wiley ... Society Located in Taipei have signed an agreement to closely ... Chemical Society . The journal will be available online from ... most extensive multidisciplinary collections of online resources, used by 10 ...
... distinct from hematopoietic cells, are an essential component ... for the long-term maintenance of hematopoietic stem cells ... stromal cells regulate the proliferation and differentiation of ... factors and extracellular matrix, and through physical cell-cell ...
Cached Biology News:Starving prostate cancer 2Journal of the Chinese Chemical Society expands international reach with Wiley-VCH 23-D long-term bone marrow culture to analyze stromal cell biological function 2
(Date:9/11/2014)... Awarded annually by Germany’s Design ... internationally recognized quality label for excellent design. METTLER ... coveted Red Dot award in recognition ... Powder Dispenser (HPD). , The Quantos Handheld ... and ease-of-use to applications involving free-flowing powders. Forget ...
(Date:9/11/2014)... WILMINGTON, Del. (PRWEB) September 11, 2014 ... LLC is excited to announce that it has ... including their two wholly owned subsidiaries, Essex ... as distributors of Zemea® USP propanediol in the ... covers the following USA eastern and mid-western states: ...
(Date:9/11/2014)... LONDON , Sept. 11, 2014 /PRNewswire/ ... the charity,s development and commercialisation arm, have reached an ... company in the emerging field of regenerative medicine, ... into clinical trials in subjects with non-small cell ... treatment to enter Cancer Research UK,s Clinical Development ...
(Date:9/11/2014)... The Stem Cell Institute, located in Panama ... cord stem cell therapy on Saturday, September 20, 2014 in ... from 1:00 pm to 4:00 pm. , Stem Cell ... “Umbilical Cord Stem Cell Clinical Trials for MS and Autism: ... of the Stem Cell Institute and Medistem Panama Inc. ...
Breaking Biology Technology:METTLER TOLEDO Handheld Powder Receives Red Dot Award for Product Design 2DuPont Tate & Lyle Bio Products Appoints Skidmore Sales as Distributor for Zemea® USP 2DuPont Tate & Lyle Bio Products Appoints Skidmore Sales as Distributor for Zemea® USP 3Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 2Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 3Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 4Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 5Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 6Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 7Cancer Research UK, Cancer Research Technology And Asterias Biotherapeutics Partner To Trial Immunotherapy Vaccine For Lung Cancer 8Stem Cell Institute Public Seminar on Adult Stem Cell Therapy Clinical Trials in San Antonio, Texas September 20th, 2014 2Stem Cell Institute Public Seminar on Adult Stem Cell Therapy Clinical Trials in San Antonio, Texas September 20th, 2014 3Stem Cell Institute Public Seminar on Adult Stem Cell Therapy Clinical Trials in San Antonio, Texas September 20th, 2014 4
... in a series of articles on developing start-up companies ... article focused on the tax law implications of employees ... unemployment insurance. , , Madison, Wis. ... test for determining independent contractor status. Although this test ...
... that a CIO's head has to be on a swivel. ... consistent theme during the Fusion 2007 CEO-CIO Symposium , ... directions, and risk management has surpassed security as the paramount ... opening keynote, where John Swainson, chief executive of CA ...
... web-centric business sector continued its crash in 2001, the directors ... their Wisconsin-based business unit. Their decision was only delayed when ... meeting in New York scheduled for that tragic day. , ... Dan Maynard pleaded with board members to keep the division ...
Cached Biology Technology:Early Stage, Step 8: Misclassifying workers brings risk 2Early Stage, Step 8: Misclassifying workers brings risk 3Early Stage, Step 8: Misclassifying workers brings risk 4Early Stage, Step 8: Misclassifying workers brings risk 5Fusion 2007: IT threats make risk management paramount 2Fusion 2007: IT threats make risk management paramount 3Connecture's Maynard finds IT business opportunity in adversity 2Connecture's Maynard finds IT business opportunity in adversity 3Connecture's Maynard finds IT business opportunity in adversity 4Connecture's Maynard finds IT business opportunity in adversity 5Connecture's Maynard finds IT business opportunity in adversity 6
...
...
... derived from the Spodoptera frugiperda Sf21 cell line ... transfections, plaque assays, virus production, and protein expression. ... optimizes recovery of viable cells after thawing. They ... Cell Medium and can also be grown in ...
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
Biology Products: