Navigation Links
Brain cells determine obesity -- not lack of willpower: Study
Date:9/8/2010

An international study has discovered the reason why some people who eat a high-fat diet remain slim, yet others pile on the weight.

The study, led in Australia by the Monash Obesity and Diabetes Institute (MODI) at Monash University, found a high-fat diet causes brain cells to become insulated from the body preventing vital signals, which tell the body to stop eating and to burn energy, from reaching the brain efficiently.

MODI director and Australian Life Scientist of the Year Professor Michael Cowley said there were two clear outcomes from the findings.

'We discovered that a high-fat diet caused brain cells to become insulated from the body, rendering the cells unable to detect signals of fullness to stop eating," Professor Cowley said.

"Secondly, the insulation also created a further complication in that the body was unable to detect signals to increase energy use and burn off calories/kilojoules."

The research showed that support cells in the brain developed overgrowth in a high-fat diet. This prevented the regular brain cells (the melanocortin system or POMC neurons) from connecting with other neural mechanisms, which determine appetite and energy expenditure.

Professor Cowley said the study findings provide a critical link in addressing the obesity epidemic.

"These neuronal circuits regulate eating behaviours and energy expenditure and are a naturally occurring process in the brain. The circuits begin to form early in life so that people may have a tendency towards obesity even before they eat their first meal," Professor Cowley said.

Eating a high fat diet causes more "insulation" in the nerve cells, and makes it even harder for the brain to help a person lose weight.

"Obese people are not necessarily lacking willpower. Their brains do not know how full or how much fat they have stored, so the brain does not tell the body to stop refuelling. Subsequently, their body's ab
'/>"/>

Contact: Samantha Blair
samantha.blair@monash.edu
61-399-034-841
Monash University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Cockroach brains could be rich stores of new antibiotics
2. The brain speaks
3. Insect brains are rich stores of new antibiotics
4. Major moral decisions use general-purpose brain circuits to manage uncertainty
5. Research heralds potential for early diagnosis of degenerative brain disorders
6. New study sheds light on painkilling system in brain
7. Gene scan finds link across array of childhood brain disorders
8. Brain connections break down as we age
9. Brain gene expression changes when honey bees go the distance
10. Boston Univ., Veterans Affairs find sports brain trauma may cause disease mimicking ALS
11. Saving the brains white matter with mutated mice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/5/2014)... -Individuals show great diversity in their ability to identify ... greatly differ in their perceptual evaluation of odors, with ... , Sex differences in olfactory detection may ... be connected to one,s perception of smell, which is ... olfactory superiority has been suggested to be cognitive or ...
(Date:11/4/2014)... (November 4, 2014) — Think about the way our ... do neighboring cells know that they are supposed to ... do these tissues find the correct place and alignment? ... these crucial questions. , In a new study, UM ... communicate with their surrounding neighbors, at the head-trunk region. ...
(Date:11/4/2014)...   Neurotechnology , a provider of high-precision ... version of its fingerprint matching algorithm has achieved ... evaluation organized by NIST. The MINEX test measures ... 378 fingerprint standard template format. MINEX compliance is ... the United States and ...
Breaking Biology News(10 mins):The female nose always knows: Do women have more olfactory neurons? 2The inside story: How the brain and skull stay together 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3
... WEST LAFAYETTE, Ind. - Honeybee populations have been in ... have identified one of the factors that cause bee ... dead in and around hives from several apiaries over ... insecticides, which are commonly used to coat corn and ...
... University of Illinois researchers have shown that by ... of metal nanoantennas, these nano-scale structures allow for ... particles. "Nanoantennas are extremely popular right ... optical fields in small areas," explained Kimani Toussaint, ...
... Calif. Scientists have long seen evidence of social behavior among ... the sea. Dolphins frolic together, lions live in packs, and ... the insects. And, right under our feet, it appears that ... the soil. Until recently, it was unknown how the worms ...
Cached Biology News:Researchers: Honeybee deaths linked to seed insecticide exposure 2Researchers: Honeybee deaths linked to seed insecticide exposure 3Optical nanoantennas enable efficient multipurpose particle manipulation 2Worm seeks worm: Caltech researchers find chemical cues driving aggregation in nematodes 2Worm seeks worm: Caltech researchers find chemical cues driving aggregation in nematodes 3
(Date:11/18/2014)... 18, 2014 Alanda Software, a ... Reporting solutions, announced today that a top tier ... Consummate Provider™ solution in both the U.S. and ... SaaS based, Data Quality remediation portal, designed to ... party Providers improve their ability to capture, transmit ...
(Date:11/18/2014)... Array Architects is proud of a ... the nation's hospitals and health systems. It is a ... their careers to the advancement of both the healthcare ... respective field, Laura Silvoy has been chosen to share ... Simulation Conference. , Laura will present her Process ...
(Date:11/18/2014)...  Novira Therapeutics, Inc., a privately held biopharmaceutical company ... B virus (HBV) infection, today announced that Brian ... Advisory Board (SAB).  "We are thrilled ... S. Schade , Chief Executive Officer of Novira.  "Brian ... be invaluable to Novira as our lead core inhibitor ...
(Date:11/16/2014)... (PRWEB) November 16, 2014 James Hill ... With Filtered Fume Hoods, 3 Years Later” scheduled for ... fall of 2011, Butler University surprised many in the ... in their organic chemistry and general chemistry teaching laboratories ... due to building age and substantial growth within the ...
Breaking Biology Technology:Alanda Software Completes Successful Implementation of Global Data Quality & Vendor Management Solution for Top Tier Global Biopharmaceutical Company 2Array Healthcare Simulation Expert Slated to Speak at Winter Simulation Conference 2Novira Therapeutics Announces Appointment of Brian F. Daniels, M.D., to its Scientific Advisory Board 2Novira Therapeutics Announces Appointment of Brian F. Daniels, M.D., to its Scientific Advisory Board 3Don't miss the I2SL High-Tech Talks Webinar Series Presenting: Butler University's Renovation With Filtered Fume Hoods, 3 Years Later 2Don't miss the I2SL High-Tech Talks Webinar Series Presenting: Butler University's Renovation With Filtered Fume Hoods, 3 Years Later 3
... ... Executive Officer of Merrimack Pharmaceuticals, will provide a company overview at the Jefferies 2010 ... ... announced that it will present at the Jefferies 2010 Global Life Sciences Conference in ...
... A team of Duke University chemists has perfected a simple ... conductors are small enough to be transparent, making them ideal ... displays. "Imagine a foldable iPad," said Benjamin Wiley, an ... findings online this week in Advanced Materials . ...
... CHAPEL HILL, N.C. , June 1 Companies invest hundreds of ... these new products to market.   , , ... on these vast investments, successful companies must maximize product uptake across all customer groups: ... win formulary access and improve product placement.   , ...
Cached Biology Technology:Merrimack Pharmaceuticals to Present at the Jefferies 2010 Global Life Sciences Conference 2Copper nanowires enable bendable displays and solar cells 2Maximize Market Research to Improve Formulary Access Within Managed Markets Sector 2Maximize Market Research to Improve Formulary Access Within Managed Markets Sector 3
... cap mat made from an inert polymer with ... 384 split septum caps for use ... Suitable for PCR when used in conjunction with ... Pierceable with standard pipetting equipment 384 septum ...
... Buffer is a unique alternative to ... (TRIS acetate-EDTA) electrophoresis buffers. Bionic Buffer ... rapid running times, and high-resolution band ... gel electrophoresis after dilution to working ...
The Mu-End™ Protein Truncation Kit provides a convenient method for generating a library of N-terminal and C-terminal protein deletions that can be expressed in E. coli....
... Mouse Cytokine Array is a multiplex sandwich ... measurement of 12 cytokines in serum; EDTA, ... Each well of the microplate provided is ... in standards and samples added to the ...
Biology Products: