Navigation Links
Brain cell communication: Why it's so fast
Date:9/21/2010

Billions of brain cells are communicating at any given moment. Like an organic supercomputer they keep everything going, from breathing to solving riddles, and "programming errors" can lead to serious conditions such as schizophrenia, Parkinson's disease and attention-deficit hyperactivity disorder.

The brain uses biochemical signal molecules

Nowadays the biochemical language of the nerve cells is the subject of intensive research right down at the molecular level, and for the first time researchers, some from the University of Copenhagen, have described just how nerve cells are capable of transmitting signals practically simultaneously.

The cells of the nervous system communicate using small molecule neurotransmitters such as dopamine, serotonin and noradrenalin. Dopamine is associated with cognitive functions such as memory, serotonin with mood control, and noradrenaline with attention and arousal.

The brain cell communication network, the synapses, transmit messages via chemical neurotransmitters packaged in small containers (vesicles) waiting at the nerve ends of the synapses. An electrical signal causes the containers and membrane to fuse and the neurotransmitters flow from the nerve ending to be captured by other nerve cells. This occurs with immense rapidity in a faction of a millisecond.

The vesicle uses three copies of the "linking bridge"

Researchers from the Universities of Copenhagen, Gttingen and Amsterdam have been studying the complex organic protein complexes that link vesicles and membrane prior to fusion, in order to find an explanation for the rapidity of these transmissions. They have discovered that the vesicle contains no fewer than three copies of the linking bridge or "SNARE complex".

With only one SNARE complex the vesicle takes longer to fuse with the membrane and the neurotransmitter is therefore secreted more slowly.

- "The precursors for t
'/>"/>

Contact: Jakob Balslev Sorensen
jakobbs@sund.ku.dk
453-089-0096
University of Copenhagen
Source:Eurekalert

Page: 1 2

Related biology news :

1. Discovery of key pathway interaction may lead to therapies that aid brain growth and repair
2. New pathway identified in Parkinsons through brain imaging
3. OU study on genetics in fruit flies leads to new method for understanding brain function
4. Investigators discover a new hot spot for the genesis of signaling neurons in the adult brain
5. Brain cells determine obesity -- not lack of willpower: Study
6. Cockroach brains could be rich stores of new antibiotics
7. The brain speaks
8. Insect brains are rich stores of new antibiotics
9. Major moral decisions use general-purpose brain circuits to manage uncertainty
10. Research heralds potential for early diagnosis of degenerative brain disorders
11. New study sheds light on painkilling system in brain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... 2014 Research and Markets ( ... "Global Facial Recognition Market 2015-2019" report ... http://photos.prnewswire.com/prnh/20130307/600769 Facial recognition is a ... recognition system measures the overall facial feature of ... and the distance between eyes. Facial recognition is ...
(Date:12/11/2014)... , Dec. 10, 2014  Data Sciences ... monitoring, has released a new series of digital ... preclinical toxicology researchers. M series, part of the ... collect the best possible physiologic data when incorporating ... Adding functional endpoints to toxicology studies has evolved ...
(Date:12/10/2014)... , Dec. 9, 2014 CIE San Diego ... that provides the connective tissue that enhances care coordination ... to easily share client-level information; earned a second $1 ... to organizations serving seniors aging in community and; will ... on December 11 th 4-6p. CIE ...
Breaking Biology News(10 mins):Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3New telemetry implants expected to change how large animal toxicology studies are conducted 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4
... JOLLA, CA-- It takes dozens of chemical reactions for a ... in every type of living organism. Cholesterol, for example, an ... isoprenoid chemical. The molecule that gives oranges their citrusy smell ... drug artemisinin. Now, researchers at the Salk Institute ...
... Biophysical Society is pleased to announce the speakers for ... in its fifth year and supported by supported by ... by young investigators at the interface of the physical ... Monday, February 17, 2014, in San Francisco, California as ...
... weaker as they age and then die, but that,s not the ... of aging at all. These are among the findings in ... this week. The study compares the aging patterns of humans ... about aging and what it should be like," said Pedro F. ...
Cached Biology News:Missing molecule in chemical production line discovered 2Missing molecule in chemical production line discovered 3Not all species age the same; humans may be outliers 2
(Date:12/24/2014)... Sigma-Aldrich Corporation (NASDAQ: SIAL ... the Hart-Scott-Rodino Antitrust Improvements Act (HSR Act) in ... 2014, thereby completing the U.S. HSR Act antitrust ... the Company by Merck KGaA, Darmstadt, Germany.  ... to closing the transaction, which remains subject to ...
(Date:12/24/2014)... and NEW YORK , ... from its open-label pilot study of mazindol in children ... Development and Therapy in December 2014 . ... mazindol in children with attention deficit/hyperactivity disorder" ( Konofal ... 2014 Dec 1;8:2321-2332. eCollection 2014 ) shows ...
(Date:12/22/2014)... 2014   Synthetic Biologics, Inc. ... therapies for serious infections and diseases, with ... announced positive topline safety and tolerability results ... SYN-004, the Company,s investigational oral beta-lactamase enzyme ... (C. difficile) infection, antibiotic-associated diarrhea and ...
(Date:12/22/2014)... CHAPEL HILL, N.C. , Dec. 22, 2014 ... ALNE) today announced that it has signed a ... biotechnology company that has developed and patented a ... and medical diagnostics products that enable rapid on-site ... and alcohol use/abuse and health issues in an ...
Breaking Biology Technology:Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 2Redefining ADHD: A New Approach & A Shift of Paradigm in ADHD Therapeutics 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 2Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 3Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 4Synthetic Biologics Announces Positive Topline Results from Phase 1a Trial of SYN-004 for the Prevention of C. difficile Infection 5ALNE Announces Intention To Acquire BioTechPharma 2
... Medical,Innovations, Inc. (Amex: IMA ), a leading provider ... a,dividend of $4.77 per share on its Series B ... paid in shares of Series B,stock in an amount ... divided by,(b) 97% of the average of the volume-weighted ...
... Sept. 15 Assay Designs and the Spinal,Muscular ... a,collaborative agreement for development of reagents and assays ... discovery and development,efforts for spinal muscular atrophy (SMA), ... toddlers. "Assay Designs is excited and proud to,have ...
... Sept. 15 Epeius Biotechnologies,Corporation today announced that ... has been highlighted in a recent NEWS article,published ... (JNCI, Sept. 9,2008). The article, authored by Vickie ... medicine that may succeed where small,molecules and proteins ...
Cached Biology Technology:Inverness Medical Innovations Declares Dividend on its Series B Convertible Perpetual Preferred Stock 2Assay Designs(TM), Inc. and the Spinal Muscular Atrophy Foundation Announce Collaboration To Accelerate the Discovery of New Therapeutics for Spinal Muscular Atrophy (SMA) 2Epeius Biotechnologies' Lead Product, Rexin-G for Metastatic Cancer, Aptly Highlighted by National Cancer Institute Journal 2
... Whether your projects are focused on sequencing, ... or in other areas of genomics and ... help you meet your research and manufacturing ... to take your project from beginning to ...
... Research Scale (gram quantities of IgY) , ... Prepare your Antigen), we segregate the appropriate number ... After 3 such eggs are collected (usually over ... injection series. This involves a total of four ...
... SOS Protein Solubility Service, We deliversoluble ... New SOS technology yields the best soluble ... applied on each clone submitted , Powerful ... ,The new protein Solubility Optimization Service (SOS) ...
... Panels were designed for full-length gene cloning ... to identify the desired cDNA clone. The ... 96-well "Master Plate," where each well contains ... the positive well(s) by gel electrophoresis of ...
Biology Products: