Navigation Links
Brain can learn to overcome sleep apnea: U of T scientist
Date:2/1/2011

TORONTO, ON New research from the University of Toronto could provide some restful nights for the 18 million North Americans who suffer from obstructive sleep apnea.

In a recent study that appeared in the Journal of Neuroscience, scientists from the University demonstrated that repeated obstruction of the airways requires release of the brain chemical noradrenaline. The release of this chemical helps the brain learn to breathe more effectively and purposefully.

"What we showed is that repeated disruption of normal lung activity what happens during sleep apnea triggers a form of learning that helps you breathe better. This type of brain plasticity could be harnessed to help overcome the breathing insufficiency that typifies sleep apnea" says Dr. John Peever, Associate Professor of neuroscience and lead author of the study.

In order to mimic the experience of severe sleep apnea, the scientists induced short 15 second apneas in sedated rats by repeatedly restricting airflow into the lungs. They found repeated apneas caused the brain to progressively trigger more forceful contraction of the respiratory muscles, which caused an increase in breathing. This increase in breathing lasted for over an hour.

Peever says it seems the brain is using the unwanted side-effects of sleep apnea to help it learn to prevent future apneas by increasing the depth of breathing.

This study also pinpointed the brain chemical that allows this type of plasticity to occur. They found that noradrenaline is required in the case of repeated apneas to cause brain plasticity and enhance breathing.

These findings are important because they suggest that artificial manipulation with common drugs that affect noradrenaline levels in the brain could also help improve breathing in patients suffering from sleep apnea. This work could serve as the potential basis for developing the long sought after pill for sleep apnea.


'/>"/>

Contact: Michael Kennedy
m.kennedy@utoronto.ca
416-946-5025
University of Toronto
Source:Eurekalert

Page: 1

Related biology news :

1. Learn more quickly by transcranial magnetic brain stimulation
2. Conversion of brain tumor cells into blood vessels thwarts treatment efforts
3. New molecule could save brain cells from neurodegeneration, stroke
4. Reducing diet early in pregnancy stunts fetal brain development
5. New technique to see neurons of the deep brain for months at a time developed at Stanford
6. LCD projector used to control brain and muscles of tiny organisms such as worms
7. Researchers show how Alzheimers plaques lead to loss of nitric oxide in brain
8. New book highlights the cellular and molecular determinants of brain wiring
9. Major advance in MRI allows much faster brain scans
10. UTHealth studies cord blood stem cells for pediatric traumatic brain injury
11. Some brain tumors mimic the genetic program of germline cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2014)... SUNNYVALE, California , December 9, 2014 /PRNewswire/ ... Integrate with ITN,s BCARD Platform ... secure, cloud-based enterprise meeting scheduling solutions for business-to-business ... International, the world leader in mobile near-field communication ... solutions.      (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , ...
(Date:12/4/2014)... , Dec. 3, 2014  Crossmatch™, a leading ... that its DigitalPersona ® Pro Enterprise software ... been deployed throughout First Bank branch locations in ... South Carolina and Virginia. First Bank, a ... Southern Pines, North Carolina , selected the ...
(Date:11/21/2014)... According to a new market research report ... Control, Intrusion Detection, Parking Management, Under Vehicle Inspection), End ... - Global Forecasts to 2020", published by MarketsandMarkets, The ... $25 Billion in 2014 and is expected to reach ... 8.69%. Browse 116 market data Tables and ...
Breaking Biology News(10 mins):Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
... computer scientists have found a cheap, quick and copyright-respecting ... resources. The software, now available in an experimental beta ... interface that works on all the most popular computer ... for researchers in neural science," says Gully A.P.C. Burns, ...
... infection with high levels of the virus associated with ... as 27 times, according to a study published in ... Prevention. , Anthony Gunnell, a medical biostatistician and ... reviewed the medical exams of women with non-invasive cervical ...
... "toggle switch" that enables them to morph into highly ... comfortably in their new surroundings, a new study in ... shift between two alternating states -- travelers and nesters ... or spreads to other parts of the body, said ...
Cached Biology News:Beyond the book: Software automates access to brain atlases 2Beyond the book: Software automates access to brain atlases 3High HPV concentrations combined with smoking significantly raise risks of cervical cancer 2High HPV concentrations combined with smoking significantly raise risks of cervical cancer 3Newly discovered behavior in cancer cells signals dangerous metastasis 2Newly discovered behavior in cancer cells signals dangerous metastasis 3
(Date:12/17/2014)... , Dec. 16, 2014  Vermillion, Inc. (NASDAQ: ... on gynecologic disease, today announced the next step in ... premier bio-analytics solutions provider with the naming of current ... and Chief Executive Officer, while current Chairman of the ... to serve as Chairman. These changes are effective January ...
(Date:12/17/2014)...   Synageva BioPharma Corp. (NASDAQ: ... rare disorders, announced today its presentation at the upcoming ... San Francisco, CA. Sanj ... present on Monday, January 12, 2015, at 9:00 a.m. ... live and may be accessed from the "Webcasts & ...
(Date:12/15/2014)... -- GlassesOff Inc. (OTCBB: GLSO) announced today the appointment of ... of the Company,s Board of Directors. Mr. ... CEO until its acquisition by Stanley Black ... as the inventor of the first Wi-Fi-based Active RFID ... RFID solutions focused on improving operational efficiency, safety and ...
(Date:12/13/2014)... 2014 /CNW/ - MaRS and Virgin Unite Canada, the non-profit ... joined forces to support Canadian entrepreneurs tackling social and environmental ... was at the MaRS Centre to announce the new partnership, ... fund. This fund has $1 million in seed capital provided ... -based Mindset Social Innovation Foundation, founded by Alison Lawton ...
Breaking Biology Technology:Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 2Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 3Vermillion Names Valerie Palmieri CEO; James LaFrance to continue as Chairman of Board 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3MaRS and Virgin Unite partner to invest in business as a force for good 2MaRS and Virgin Unite partner to invest in business as a force for good 3
... MBA to Join Genencor,s Senior Management Team, ... of Danisco,A/S, today announced that Dr. Glenn E. ... - Technical Enzymes, effective Oct. 1, 2007. As ... Nedwin will head the,division,s activities in Grain Processing ...
... 1 ISTO Technologies, Inc., a privately,held ... States Patent,Office granted a key patent protecting ... "Method for Chondrocyte Expansion with,Phenotype Retention." ... regeneration and,repair in knee joints and spinal ...
... BERKELEY, Calif., Oct. 1 Berkeley BioSciences, Inc.,co-founded ... of the,Department of Nutritional Sciences at UC Berkeley ... of Health Cancer Research Program at UC,Berkeley, announces ... support,formula exclusively licensed from UC Berkeley.,( http://www.ActivaMune.com/ ). ...
Cached Biology Technology:Genencor Appoints New Executive Vice President - Technical Enzymes 2ISTO Technologies Granted Key Patent for Cartilage Cell Expansion by the United States Patent Office 2Advanced Immune Support Formula Licensed From UC Berkeley Launched 2
Rabbit polyclonal to VEZT ( Abpromise for all tested applications). Antigen: Full length human VEZT conjugated to GST Entrez Gene ID: 55591 Swiss Protein ID: Q9HBM0...
Phospho-4E-BP1 (Thr37/46) (236B4) Rabbit mAb Shipping Temperature: Cold Storage Temperature: -20C...
Goat polyclonal to FBXO2 ( Abpromise for all tested applications). entrezGeneID: 26232 SwissProtID: Q9UK22...
Anti-Dardarin Immunogen: Synthetic peptide from rat LRRK2. Available Date: 38814...
Biology Products: