Navigation Links
Brain can learn to overcome sleep apnea: U of T scientist
Date:2/1/2011

TORONTO, ON New research from the University of Toronto could provide some restful nights for the 18 million North Americans who suffer from obstructive sleep apnea.

In a recent study that appeared in the Journal of Neuroscience, scientists from the University demonstrated that repeated obstruction of the airways requires release of the brain chemical noradrenaline. The release of this chemical helps the brain learn to breathe more effectively and purposefully.

"What we showed is that repeated disruption of normal lung activity what happens during sleep apnea triggers a form of learning that helps you breathe better. This type of brain plasticity could be harnessed to help overcome the breathing insufficiency that typifies sleep apnea" says Dr. John Peever, Associate Professor of neuroscience and lead author of the study.

In order to mimic the experience of severe sleep apnea, the scientists induced short 15 second apneas in sedated rats by repeatedly restricting airflow into the lungs. They found repeated apneas caused the brain to progressively trigger more forceful contraction of the respiratory muscles, which caused an increase in breathing. This increase in breathing lasted for over an hour.

Peever says it seems the brain is using the unwanted side-effects of sleep apnea to help it learn to prevent future apneas by increasing the depth of breathing.

This study also pinpointed the brain chemical that allows this type of plasticity to occur. They found that noradrenaline is required in the case of repeated apneas to cause brain plasticity and enhance breathing.

These findings are important because they suggest that artificial manipulation with common drugs that affect noradrenaline levels in the brain could also help improve breathing in patients suffering from sleep apnea. This work could serve as the potential basis for developing the long sought after pill for sleep apnea.


'/>"/>

Contact: Michael Kennedy
m.kennedy@utoronto.ca
416-946-5025
University of Toronto
Source:Eurekalert

Page: 1

Related biology news :

1. Learn more quickly by transcranial magnetic brain stimulation
2. Conversion of brain tumor cells into blood vessels thwarts treatment efforts
3. New molecule could save brain cells from neurodegeneration, stroke
4. Reducing diet early in pregnancy stunts fetal brain development
5. New technique to see neurons of the deep brain for months at a time developed at Stanford
6. LCD projector used to control brain and muscles of tiny organisms such as worms
7. Researchers show how Alzheimers plaques lead to loss of nitric oxide in brain
8. New book highlights the cellular and molecular determinants of brain wiring
9. Major advance in MRI allows much faster brain scans
10. UTHealth studies cord blood stem cells for pediatric traumatic brain injury
11. Some brain tumors mimic the genetic program of germline cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2017)... 2017 Research and Markets has announced the ... Trends - Industry Forecast to 2025" report to their offering. ... The Global ... of around 8.8% over the next decade to reach approximately $14.21 ... market estimates and forecasts for all the given segments on global ...
(Date:3/22/2017)... 21, 2017 Optimove , provider ... retailers such as 1-800-Flowers and AdoreMe, today announced ... and Replenishment. Using Optimove,s machine learning algorithms, these ... and replenishment recommendations to their customers based not ... of customer intent drawn from a complex web ...
(Date:3/20/2017)... HANOVER, Germany , March 20, 2017 At ... Hamburg -based biometrics manufacturer DERMALOG. The Chancellor came to the ... Japan is this year,s CeBIT partner country. At the largest ... important biometrics in use: fingerprint, face and iris recognition as well as ... ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... -- Dutch philosopher Koert van Mensvoort - founder of the ... Technology in Eindhoven - has written a ,Letter to Humanity, in ... to avoid becoming a slave and victim to its own technology, but to ... ... Koert van Mensvoort – founder of the Next Nature Network and Fellow of ...
(Date:4/19/2017)... ... April 18, 2017 , ... A number of new instruments have ... is part of the Protein and Cell Analysis Education Webinar Series , will ... technology fits in current and future applications. , Many flow cytometers have unique ...
(Date:4/19/2017)... ... April 19, 2017 , ... ThermaGenix, ... round. This event adds to several other early achievements at ThermaGenix, including the ... Teams. , ThermaGenix will use proceeds from the Series A-1 round ...
(Date:4/19/2017)... 19, 2017  As a Bronze Sponsor ... Summit ,  Proove® Biosciences, Inc. announces the ... and lifestyle factors to accurately predict prescription opioid ... Southern California (USC), the Interventional Pain Institute in ... results showing that Proove Opioid Risk® accurately identifies ...
Breaking Biology Technology: