Navigation Links
Brain abnormalities in Parkinson's patients develop before symptoms occur
Date:1/20/2010

Scientists who have identified brain networks damaged in Parkinson's disease have new evidence that these systems become abnormal a few years before symptoms appear. And what's more, parts of the network appear to respond in a last ditch attempt to rescue the brain.

"We were surprised," said Chris Tang, MD, PhD, a Parkinson's investigator at The Feinstein Institute for Medical Research in Manhasset, NY, and an author of the study, published this month in the Journal of Neuroscience. The Feinstein scientists have been following people with Parkinson's disease for decades. They have had a unique opportunity to take snapshots of the brain over the course of four years in 15 patients and an equal number of normal volunteers. The group initially identified two discrete abnormal networks, one that was involved in mediating the motor symptoms of Parkinson's disease, and the other that regulates the cognitive dysfunction that develops in many patients with this illness.

Symptoms of Parkinson's disease initially occur on one side of the body, which provided scientists with a unique opportunity to study the brain scans at multiple times and compare the symptoms to changes in the brain networks over time. The idea for the latest study was to watch the activity of the network on the side of the brain that controls the side of the body that's free of symptoms. As the disease progresses, both sides of the body ultimately become involved.

The motor network that governed the side of the body with initial symptoms was the first to become abnormal. Scientists under the direction of David Eidelberg, MD, head of the Feinstein's Center for Neurosciences, found that the motor network on the other side of the brain was also abnormal, even though symptoms appeared only two years later. The brain network that governs cognition began showing abnormalities after two more years had passed, which was four years after their diagnosis. The average age of
'/>"/>

Contact: Jamie Talan
jtalan@nshs.edu
516-562-1232
North Shore-Long Island Jewish (LIJ) Health System
Source:Eurekalert

Page: 1 2

Related biology news :

1. Invasion of the brain tumors
2. HIV is a double hit to the brain
3. AIDS interferes with stem cells in the brain
4. 60 second test could help early diagnosis of common brain diseases
5. U of MN researchers discover noninvasive diagnostic tool for brain diseases
6. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
7. Influence of sex and handedness on brain is similar in capuchin monkeys and humans
8. Inside the brain of a crayfish
9. Specific brain protein required for nerve cell connections to form and function
10. Brains timing linked with timescales of the natural visual world
11. Adult brain can change, study confirms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... that have seen an increase in so-called "nuisance flooding"--which ... storm drains and compromised infrastructure--are on the East Coast, ... nuisance flooding, caused by rising sea levels, has increased ... percent since the 1960s. , The report, Sea Level ... States, also finds Annapolis and Baltimore, Maryland, lead the ...
(Date:7/28/2014)... study suggest two ways to effectively address the problem that ... women, compared to women of a normal body mass index. ... but as the population has increased in weight, concern has ... Studies have consistently found that obesity has a negative impact ... affect how well the pill prevents pregnancy. , ...
(Date:7/28/2014)... MANHATTAN, Kansas He calls himself the bug hunter, ... that can only be found and identified with special ... at the Kansas State Veterinary Diagnostic Laboratory at Kansas ... his discoveries, porcine enterovirus G, which is an important ... a virus in cells, but didn,t know what it ...
Breaking Biology News(10 mins):NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 3Strategies identified to improve oral contraceptive success with obese women 2Researcher using next-generation sequencing to rapidly identify pathogens 2Researcher using next-generation sequencing to rapidly identify pathogens 3
... CA November 29, 2010 - For Immediate Release ... uncovered a previously unknown regulatory mechanism in the body,s response ... challenge a long-held dogma in the field of immunology and ... be administered to the origin of autoimmunity. The results ...
... A broad review of current research on nuclear power economics ... Sustainable Energy . The report concludes that nuclear power will ... current fuel cycle is not sustainable. Due to uncertainty about ... on basic assumptions that are not grounded in real data. ...
... who linked eating tomatoes with a reduced risk of ... them trace the metabolism of tomato carotenoids in the ... Institutes of Health to do it. "Scientists believe ... orange colors to some fruits and vegetablesprovide the cancer-preventive ...
Cached Biology News:Scripps Research scientists redefine the role of plasma cells in the immune system 2Scripps Research scientists redefine the role of plasma cells in the immune system 3Scripps Research scientists redefine the role of plasma cells in the immune system 4U of I scientists develop tool to trace metabolism of cancer-fighting tomato compounds 2
(Date:7/28/2014)... VA (PRWEB) July 28, 2014 The ... nonprofit authority on the use of health IT to ... Health Plan Identifier (HPID) Workgroup has developed ... a Health Plan and Payer?” The HPID Workgroup, a ... closely with the Centers for Medicare and Medicaid Services ...
(Date:7/28/2014)... -   JOLT , a leading technology accelerator, announced ... growing portfolio of startups. Next-level tech and boundary-pushing innovation ... JOLT accelerator, and Cohort four is no exception, with ... Since its launch in July 2012, JOLT has produced ... Now at 23 investments, JOLT,s portfolio has an overall ...
(Date:7/28/2014)... MO (PRWEB) July 28, 2014 ... and services that bring the power of genomics to ... inaugural Appistry Pipeline Challenge . , Two ... president of the National Center for Genome Resources, and ... Hospitals and Clinics of Kansas City. Rounding out the ...
(Date:7/28/2014)... , July 28, 2014 Research and ... Particle Size Analysis Market 2014-2018" report to their offering. ... Particle size analysis is a technique used to determine the ... or liquid. It is crucial to analyze the size of ... Therefore, particle size analysis is performed to determine the behavior ...
Breaking Biology Technology:WEDI’s HPID Workgroup Announces Release of Issue Brief: “What is the Difference Between a Health Plan and Payer?” 2JOLT Announces the Next 6 Startups to Join its Summer 2014 Cohort 2JOLT Announces the Next 6 Startups to Join its Summer 2014 Cohort 3Appistry Names Industry Experts from the National Center for Genome Resources and Mercy Children's, Kansas City, to Judge Pipeline Challenge Competition 2Global Particle Size Analysis Market 2014-2018 2
... Document on Microsoft XP addresses vulnerabilities , ,We have ... of the seminar audience, hold up his or her laptop ... include: encrypted files system, better passwords and physical cabling. The ... good enough. All those suggestions can be bypassed." Finally, ...
... springs legislative debate on the pros and cons of a ... than a few Wisconsin lawmakers had their doubts about the ... debate rolls around, lets hope members of the Senate and ... in the growing U.S. economy. It should turn doubters into ...
... the availability of its @ctiveView Web platform, software designed ... a wide range of electronic sources within an online ... and competitive trademark clearance and protection services within a ... able to integrate references from both traditional trademark data ...
Cached Biology Technology:How to increase your online security 2How to increase your online security 3Venture-backed companies drive job creation, even in tough times 2NameProtect announces Web-enhanced trademark software 2
...
Ultra-sensitive, non-radioactive detection of rat Osteopontin...
Agarose-LE, 250 g. Suitable for soft agarose cloning. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1200 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Request Info...
Biology Products: