Navigation Links
Brain, repair thyself: Studies highlight brain's resiliency to damage
Date:11/15/2011

Washington New research released today demonstrates the brain's remarkable capacity to repair itself. The animal studies, which propose ways to prevent or limit damage after blood and oxygen deprivation and blood clots, were presented at Neuroscience 2011, the Society for Neuroscience's annual meeting and the world's largest source of emerging news about brain science and health.

Stroke is the number one cause of long-term disability and the third leading cause of death in the developed world. Limiting the damage caused by stroke would improve patient prognosis.

Today's new findings report:

  • Sensory stimulation protects against stroke damage if administered within the first two hours of stroke onset, whether animals were awake or anesthetized (Ron Frostig, PhD, abstract 781.15, see attached summary).

  • An animal study suggests that auditory stimulation delivered soon after a stroke protects from damage (Ron Frostig, PhD, abstract 781.14, see attached summary).

  • An animal study identifies a cellular mechanism that blood vessels use to clear their own clots (Jaime Grutzendler, MD, abstract 891.17, see attached summary).

Other recent findings discussed show that:

  • Oxygen deprivation in very premature babies born before their lungs are fully developed can interfere with myelin, the fatty protective structures surrounding nerve cells. Animal studies discussed today define cellular changes that lead to white matter damage in preemies, and molecular pathways that can be potentially targeted to promote repair (Vittorio Gallo, PhD, see attached speaker summary).

A human study identifies that a protein called AXIN2 is affected by white matter injuries in infants. Further research showed that mice given a drug preventing AXIN2 destruction repaired myelin faster than other mice, suggesting AXIN2 may be an important therapeutic target (David Rowitch, MD, PhD, see attached speaker summary).

"The brain is remarkably robust," said press conference moderator Mark Paul Goldberg, MD, a neurologist at the University of Texas Southwestern Medical Center and an expert in brain injury. "Many of the brain's systems have mechanisms that allow it to protect or repair itself. With the help of further research we can better understand these mechanisms and find new applications for treating brain injuries."


'/>"/>

Contact: Kat Snodgrass
ksnodgrass@sfn.org
Society for Neuroscience
Source:Eurekalert

Related biology news :

1. MIT: Mimicking the brain, in silicon
2. For hearing parts of brain, deafness reorganizes sensory inputs, not behavioral function
3. Zombie ants have fungus on the brain, new research reveals
4. Supplement may prevent alcohol-related brain, skull defects
5. Regular aerobic exercise is good for the brain, Pitt team says
6. Experimental drug shows promise against brain, prostate cancers
7. UR study reveals chemos toxicity to brain, possible treatment
8. Knee injuries may start with strain on the brain, not the muscles
9. Social interactions can alter gene expression in the brain, and vice versa
10. UC Davis researchers discover complexities of DNA repair
11. Clemson University biochemists identify new genetic code repair tool
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/9/2016)... 9, 2016  Crossmatch ® , a leading ... today announced the addition of smart features to ... multi-factor authentication platform. New contextual and application-specific authentication ... security where it,s needed most — while minimizing ... . --> Washington, DC ...
(Date:3/3/2016)... and DE SOTO, Kansas , ... Stroke Detection Plus® to offer Oncimmune,s Early CDT®-Lung, ... and early detection of lung cancer Early ... unions and individuals. --> Early CDT®-Lung test ... individuals. --> Oncimmune, a leader in early ...
(Date:3/1/2016)... FRANCISCO , March 1, 2016  (RSAC Booth ... year, but a whopping $118 billion is lost to ... to overzealous and inaccurate fraud detection. At the RSA ... in the way companies handle authentication by devaluing the ... and behavioral analytics. --> ...
Breaking Biology News(10 mins):
(Date:4/27/2016)... , April 27, 2016 ... (CSE: NSK) (OTCPink: NSKQB) ( Frankfurt ... an ihre Pressemitteilung vom 13. August 2015 die ... ihre Finanzen um zusätzliche 200.000.000 Einheiten auf 400.000.000 ... Dollar zu bringen. Davon wurden 157.900.000 Einheiten mit ...
(Date:4/27/2016)... ... 2016 , ... PathSensors, Inc., a leading environmental testing company, ... assist PathSensors in expanding the use of the company’s CANARY® technology in the ... for the detection of harmful pathogens, including a number of bacteria, viruses, toxins, ...
(Date:4/27/2016)... MedDay, a biotechnology company focused on the treatment of ... as Chairman of its Board of Directors. Catherine ... who contributed to the rapid development of the Company since ... her career in strategy consulting and investment banking in ...  She held C-Suite level roles in some of ...
(Date:4/26/2016)... ... , ... The European Patent Office (EPO) today announced that ... the European Inventor Award 2016 in the category "Non-European countries." The winners of the ... in Lisbon on June 9th. , The human capacity to walk with fluidity is ...
Breaking Biology Technology: