Navigation Links
Brain, repair thyself: Studies highlight brain's resiliency to damage

Washington New research released today demonstrates the brain's remarkable capacity to repair itself. The animal studies, which propose ways to prevent or limit damage after blood and oxygen deprivation and blood clots, were presented at Neuroscience 2011, the Society for Neuroscience's annual meeting and the world's largest source of emerging news about brain science and health.

Stroke is the number one cause of long-term disability and the third leading cause of death in the developed world. Limiting the damage caused by stroke would improve patient prognosis.

Today's new findings report:

  • Sensory stimulation protects against stroke damage if administered within the first two hours of stroke onset, whether animals were awake or anesthetized (Ron Frostig, PhD, abstract 781.15, see attached summary).

  • An animal study suggests that auditory stimulation delivered soon after a stroke protects from damage (Ron Frostig, PhD, abstract 781.14, see attached summary).

  • An animal study identifies a cellular mechanism that blood vessels use to clear their own clots (Jaime Grutzendler, MD, abstract 891.17, see attached summary).

Other recent findings discussed show that:

  • Oxygen deprivation in very premature babies born before their lungs are fully developed can interfere with myelin, the fatty protective structures surrounding nerve cells. Animal studies discussed today define cellular changes that lead to white matter damage in preemies, and molecular pathways that can be potentially targeted to promote repair (Vittorio Gallo, PhD, see attached speaker summary).

A human study identifies that a protein called AXIN2 is affected by white matter injuries in infants. Further research showed that mice given a drug preventing AXIN2 destruction repaired myelin faster than other mice, suggesting AXIN2 may be an important therapeutic target (David Rowitch, MD, PhD, see attached speaker summary).

"The brain is remarkably robust," said press conference moderator Mark Paul Goldberg, MD, a neurologist at the University of Texas Southwestern Medical Center and an expert in brain injury. "Many of the brain's systems have mechanisms that allow it to protect or repair itself. With the help of further research we can better understand these mechanisms and find new applications for treating brain injuries."


Contact: Kat Snodgrass
Society for Neuroscience

Related biology news :

1. MIT: Mimicking the brain, in silicon
2. For hearing parts of brain, deafness reorganizes sensory inputs, not behavioral function
3. Zombie ants have fungus on the brain, new research reveals
4. Supplement may prevent alcohol-related brain, skull defects
5. Regular aerobic exercise is good for the brain, Pitt team says
6. Experimental drug shows promise against brain, prostate cancers
7. UR study reveals chemos toxicity to brain, possible treatment
8. Knee injuries may start with strain on the brain, not the muscles
9. Social interactions can alter gene expression in the brain, and vice versa
10. UC Davis researchers discover complexities of DNA repair
11. Clemson University biochemists identify new genetic code repair tool
Post Your Comments:
(Date:11/9/2015)... , Nov. 09, 2015 ... the addition of the "Global Law ... their offering. --> ) ... "Global Law Enforcement Biometrics Market 2015-2019" ... Research and Markets ( ) has ...
(Date:10/29/2015)... , Oct. 29, 2015  The J. Craig Venter ... titled, "DNA Synthesis and Biosecurity: Lessons Learned and Options ... of Health and Human Services guidance for synthetic biology ... --> --> ... has the potential to pose unique biosecurity threats. It ...
(Date:10/29/2015)... YORK , Oct. 29, 2015 ... technology, announced a partnership with 2XU, a global ... to deliver a smart hat with advanced bio-sensing ... and other athletes to monitor key biometrics to ... the strategic partnership, the two companies will bring together ...
Breaking Biology News(10 mins):
(Date:11/26/2015)... 26, 2015 ... Accutest Research Laboratories, a leading independent ... (CRO), has formed a strategic partnership ... Temple Health for joint work on ... ) , --> ...
(Date:11/25/2015)... November 26, 2015 ... Market 2016 - 2020 report analyzes that automating ... and quality in long-term samples, minimizing manual errors, ... Automation minimizes manual errors such as mislabeling or ... Further, it plays a vital role in blood ...
(Date:11/25/2015)... , November 25, 2015 2 ... première fois les différences entre les souches bactériennes ... celles des êtres humains . Ces recherches ... et envisager la prise en charge efficace de ... diagnostiqués chez les chats .    --> ...
(Date:11/25/2015)... HOLLISTON, Mass. , Nov. 25, 2015 /PRNewswire/ ... ), a biotechnology company developing bioengineered organ implants for ... will present at the LD Micro "Main Event" ... p.m. PT. The presentation will be webcast live and ... will also be available at the conference for one-on-one ...
Breaking Biology Technology: