Navigation Links
Brain, repair thyself: Studies highlight brain's resiliency to damage
Date:11/15/2011

Washington New research released today demonstrates the brain's remarkable capacity to repair itself. The animal studies, which propose ways to prevent or limit damage after blood and oxygen deprivation and blood clots, were presented at Neuroscience 2011, the Society for Neuroscience's annual meeting and the world's largest source of emerging news about brain science and health.

Stroke is the number one cause of long-term disability and the third leading cause of death in the developed world. Limiting the damage caused by stroke would improve patient prognosis.

Today's new findings report:

  • Sensory stimulation protects against stroke damage if administered within the first two hours of stroke onset, whether animals were awake or anesthetized (Ron Frostig, PhD, abstract 781.15, see attached summary).

  • An animal study suggests that auditory stimulation delivered soon after a stroke protects from damage (Ron Frostig, PhD, abstract 781.14, see attached summary).

  • An animal study identifies a cellular mechanism that blood vessels use to clear their own clots (Jaime Grutzendler, MD, abstract 891.17, see attached summary).

Other recent findings discussed show that:

  • Oxygen deprivation in very premature babies born before their lungs are fully developed can interfere with myelin, the fatty protective structures surrounding nerve cells. Animal studies discussed today define cellular changes that lead to white matter damage in preemies, and molecular pathways that can be potentially targeted to promote repair (Vittorio Gallo, PhD, see attached speaker summary).

A human study identifies that a protein called AXIN2 is affected by white matter injuries in infants. Further research showed that mice given a drug preventing AXIN2 destruction repaired myelin faster than other mice, suggesting AXIN2 may be an important therapeutic target (David Rowitch, MD, PhD, see attached speaker summary).

"The brain is remarkably robust," said press conference moderator Mark Paul Goldberg, MD, a neurologist at the University of Texas Southwestern Medical Center and an expert in brain injury. "Many of the brain's systems have mechanisms that allow it to protect or repair itself. With the help of further research we can better understand these mechanisms and find new applications for treating brain injuries."


'/>"/>

Contact: Kat Snodgrass
ksnodgrass@sfn.org
Society for Neuroscience
Source:Eurekalert

Related biology news :

1. MIT: Mimicking the brain, in silicon
2. For hearing parts of brain, deafness reorganizes sensory inputs, not behavioral function
3. Zombie ants have fungus on the brain, new research reveals
4. Supplement may prevent alcohol-related brain, skull defects
5. Regular aerobic exercise is good for the brain, Pitt team says
6. Experimental drug shows promise against brain, prostate cancers
7. UR study reveals chemos toxicity to brain, possible treatment
8. Knee injuries may start with strain on the brain, not the muscles
9. Social interactions can alter gene expression in the brain, and vice versa
10. UC Davis researchers discover complexities of DNA repair
11. Clemson University biochemists identify new genetic code repair tool
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2016)... American College of Medical Genetics and Genomics was once again ... of the fastest-growing trade shows during the Fastest 50 Awards ... Las Vegas . Winners are ... of the following categories: net square feet of paid exhibit ... 2015 ACMG Annual Meeting was ranked 23 out of 50 ...
(Date:6/16/2016)... FRANCISCO , June 16, 2016 ... size is expected to reach USD 1.83 ... by Grand View Research, Inc. Technological proliferation and ... banking applications are expected to drive the market ... ) , The development of advanced ...
(Date:6/3/2016)... 3, 2016 Das ... Nepal hat ein 44 ... geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, ... Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte ... Januar teilgenommen, aber Decatur wurde als konformste ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... , June 23, 2016   Boston ... of novel compounds designed to target cancer stemness ... has been granted Orphan Drug Designation from the ... treatment of gastric cancer, including gastroesophageal junction (GEJ) ... inhibitor designed to inhibit cancer stemness pathways by ...
(Date:6/23/2016)... , June 23, 2016  The Prostate Cancer Foundation (PCF) is ... treatments and faster cures for prostate cancer. Members of the Class of 2016 ... countries. Read More About the Class of 2016 PCF ... ... ...
(Date:6/23/2016)... NC (PRWEB) , ... June 23, 2016 , ... In ... University Hospital in Denmark detail how a patient who developed lymphedema after being treated ... tissue. The results could change the paradigm for dealing with this debilitating, frequent side ...
(Date:6/23/2016)... ... June 23, 2016 , ... ClinCapture, the only free ... and will showcase its product’s latest features from June 26 to June 30, ... poster on Disrupting Clinical Trials in The Cloud during the conference. DIA ...
Breaking Biology Technology: